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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
Through collaboration, Vernalis will get access to the Hit ID platforms to produce the target protein, and to identify and characterise small molecule inhibitors of the oncology target.
Under the agreement, Boehringer exercised its option to license a number of cancer antigens discovered and validated using Enara Bio’s Dark Antigen discovery platform, EDAPT® and intends to develop novel off-the-shelf vaccines against non-small cell lung cancer (NSCLC).
Under the expanded collaboration, Sanofi is adding a new discovery stage programme identified and initially advanced by Exscientia, which has designed a novel lead series with data showing good potency and selectivity towards the target and differentiated molecular properties.
The company will use the net proceeds to discover and develop novel T cell receptor (TCR) therapeutics for cancer indications as well as inflammatory disorders.
The extended collaboration aims to advance immune checkpoint inhibitors in cancer by leveraging Antiverse’s AI-driven antibody discovery platform. The initial collaboration resulted in the generation of anti-PD-1 antibodies, with 2 candidates entering preclinical development.
LabGenius is pioneering the development of an ML-driven protein engineering platform. To date, EVA has co-optimised mono- and multi-specific single domain antibodies for biochemical and biofunctional properties, including stability, potency and selective tumour cell killing.
Under the agreement with MSD, Curve will discover and validate novel small molecule modulators of up to five therapeutic targets using its Microcycle® technology, initially for oncology and neurology indications.
The financing will be used to invest in Engitix’s internal drug discovery pipeline through IND-enabling studies, expand its ECM discovery platform and bioinformatics capabilities into new therapeutic areas, and to expand its team, facilities and operations.
Under the term of agreement Sanofi is collaborating with Exscientia to develop up to 15 small molecules using Exscientia’s AI-driven platform for oncology and immunology targets.
The expanded Series A funding will support the progress of internal programmes in ovarian cancer, and a second cancer indication in addition to further advancing the company's unique technology platforms.