[{"orgOrder":0,"company":"Ohara Pharmaceutical","sponsor":"BTG Specialty Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Pharmacology\/Toxicology","country":"JAPAN","productType":"Enzyme","year":"2021","type":"Inapplicable","leadProduct":"Glucarpidase","moa":"Methotrexate","graph1":"Pharmacology\/Toxicology","graph2":"Approved FDF","graph3":"Ohara Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Toxicology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Ohara Pharmaceutical \/ BTG Specialty Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Ohara Pharmaceutical \/ BTG Specialty Pharmaceuticals"},{"orgOrder":0,"company":"Ohara Pharmaceutical","sponsor":"Kiminori Kimura, MD","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"JAPAN","productType":"Undisclosed","year":"2019","type":"Inapplicable","leadProduct":"OP-724","moa":"CBP\/beta-catenin","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase I","graph3":"Ohara Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ohara Pharmaceutical \/ Kiminori Kimura, MD","highestDevelopmentStatusID":"6","companyTruncated":"Ohara Pharmaceutical \/ Kiminori Kimura, MD"},{"orgOrder":0,"company":"Ohara Pharmaceutical","sponsor":"Kiminori Kimura, MD","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"JAPAN","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"OP-724","moa":"CBP\/beta-catenin","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase I","graph3":"Ohara Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ohara Pharmaceutical \/ Kiminori Kimura, MD","highestDevelopmentStatusID":"6","companyTruncated":"Ohara Pharmaceutical \/ Kiminori Kimura, MD"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : Voraxaze® is a carboxypeptidase indicated to reduce toxic plasma methotrexate concentration (greater than 1 micromole per liter) in adult and pediatric patients with delayed methotrexate clearance due to impaired renal function.

                          Product Name : Megludase

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          September 28, 2021

                          Lead Product(s) : Glucarpidase

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Approved FDF

                          Sponsor : BTG Specialty Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : OP-724 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Liver Cirrhosis.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          December 29, 2020

                          Lead Product(s) : OP-724

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase I

                          Sponsor : Kiminori Kimura, MD

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : OP-724 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Liver Cirrhosis, Biliary.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          August 06, 2019

                          Lead Product(s) : OP-724

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase I

                          Sponsor : Kiminori Kimura, MD

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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