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                            01

                            Arecor

                            United Kingdom arrow
                            Discovery Europe
                            Not Confirmed

                            Arecor

                            United Kingdom arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : Nimacimab,Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Skye Bioscience

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Skye Bioscience Partners with Arecor to Improve Obesity Drug Nimacimab

                            Details : Under the agreement, Skye will fund Arecor’s development activities with the option to license rights to the new formulation of nimacimab and to further develop & commercialize the product.

                            Product Name : RYI-018

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            May 19, 2025

                            Lead Product(s) : Nimacimab,Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Skye Bioscience

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            02

                            Caliway Biopharmaceuticals

                            Taiwan arrow
                            Discovery Europe
                            Not Confirmed

                            Caliway Biopharmaceuticals

                            Taiwan arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : CBL-514

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Caliway Holds Successful EOP2 Meeting With FDA for CBL-514 Fat Reduction

                            Details : CBL-514 is a potentially first-in-class small-molecule drug, is an injection lipolysis drug that can induce adipocytes apoptosis and lipolysis. It is being evaluated for subcutaneous fat reduction.

                            Product Name : CBL-514

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 14, 2025

                            Lead Product(s) : CBL-514

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Palatin Technologies

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Palatin Technologies

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : Bremelanotide Acetate,Tirzepatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Alliance Global Partners

                            Deal Size : $23.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Palatin Technologies Announces Pricing of up to $23 Million Public Offering

                            Details : The net proceeds from the offering will be used to fund the developement of Vyleesi (bremelanotide acetate), which is being evaluated in mid-stage clinical trial studies for the treatment of obesity.

                            Product Name : Vyleesi

                            Product Type : Peptide

                            Upfront Cash : Undisclosed

                            May 07, 2025

                            Lead Product(s) : Bremelanotide Acetate,Tirzepatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Alliance Global Partners

                            Deal Size : $23.0 million

                            Deal Type : Public Offering

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                            04

                            Zealand Pharma

                            Denmark arrow
                            Discovery Europe
                            Not Confirmed

                            Zealand Pharma

                            Denmark arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : Petrelintide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Zealand Enrolls First in ZUPREME-2 Trial of Petrelintide for Obesity And T2D

                            Details : ZP8396 (petrelintide) is a long-acting amylin analog suitable for once-weekly subcutaneous administration that has been designed for the treatment of obesity.

                            Product Name : ZP8396

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            April 24, 2025

                            Lead Product(s) : Petrelintide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Endevica Bio

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Endevica Bio

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : Mifomelatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Endevica Doses First Patient in Phase 2 Trial for Metastatic Colorectal Cancer

                            Details : TCMCB07 is a melanocortin‐3/4 antagonist peptide candidate in clinical development for the treatment of cachexia in patients with stage 4 metastatic colorectal cancer.

                            Product Name : TCMCB07

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            April 17, 2025

                            Lead Product(s) : Mifomelatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Palatin Technologies

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Palatin Technologies

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : Bremelanotide Acetate,Tirzepatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palatin Sees Positive Appetite Suppression in Obesity Study with Bremelanotide Combo

                            Details : Vyleesi (bremelanotide) is a melanocortin receptor agonist (MCR), which is being evaluated in combination with tirzepatide for obesity.

                            Product Name : Vyleesi

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            April 17, 2025

                            Lead Product(s) : Bremelanotide Acetate,Tirzepatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Palatin Technologies

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Palatin Technologies

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : Bremelanotide Acetate,Tirzepatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palatin's MC4R Agonist Bremelanotide with GLP-1/GIP Tirzepatide Hits Ph 2 Goal

                            Details : Vyleesi (bremelanotide) is a melanocortin receptor 4 agonist (MCR4), which is being evaluated in combination with tirzepatide for obesity.

                            Product Name : Vyleesi

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            March 31, 2025

                            Lead Product(s) : Bremelanotide Acetate,Tirzepatide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Viking Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Viking Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : VK2735

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Viking Therapeutics Completes Phase 2 Enrollment for VK2735 Tablet in Obesity

                            Details : Viking investigational product VK2735, which is a Dual GLP-1/GIP Receptor Agonist. Currently, it is being evaluated in the phase I clinical trial studies for the treatment related to obesity.

                            Product Name : VK2735

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            March 26, 2025

                            Lead Product(s) : VK2735

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            The United Laboratories

                            Hong Kong arrow
                            Discovery Europe
                            Not Confirmed

                            The United Laboratories

                            Hong Kong arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : UBT251

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Novo Nordisk

                            Deal Size : $2,000.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            United Labs & Novo Sign Exclusive Deal for GLP-1/GIP/Glucagon Agonist UBT251

                            Details : Under the license agreement, Novo will obtain exclusive worldwide rights (excluding Chinese mainland, Hong Kong, Macau, and Taiwan) to develop and commercialize UBT251 for obesity.

                            Product Name : UBT251

                            Product Type : Peptide

                            Upfront Cash : $200.0 million

                            March 24, 2025

                            Lead Product(s) : UBT251

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Novo Nordisk

                            Deal Size : $2,000.0 million

                            Deal Type : Licensing Agreement

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                            10

                            Zealand Pharma

                            Denmark arrow
                            Discovery Europe
                            Not Confirmed

                            Zealand Pharma

                            Denmark arrow
                            Discovery Europe
                            Not Confirmed
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                            Lead Product(s) : Petrelintide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Zealand Completes Phase 2b Enrollment for Petrelintide in Obesity

                            Details : ZP8396 (petrelintide) is a long-acting amylin analog suitable for once-weekly subcutaneous administration that has been designed for the treatment of obesity.

                            Product Name : ZP8396

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            March 17, 2025

                            Lead Product(s) : Petrelintide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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