
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : NRG5051
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : SV Health Investors
Deal Size : $67.0 million
Deal Type : Series B Financing
NRG Therapeutics Announces Oversubscribed Series B Financing
Details : The financing will enable NRG Therapeutics to deliver clinical proof of concept in ALS/MND with NRG5051, a first-in-class, oral inhibitor of the mitochondrial permeability transition pore (mPTP).
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 08, 2025
Lead Product(s) : NRG5051
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : SV Health Investors
Deal Size : $67.0 million
Deal Type : Series B Financing

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Lead Product(s) : NRG5051
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : $5.0 million
Deal Type : Funding
NRG Selects NRG5051 Candidate with Michael J. Fox Foundation Grant for mPTP
Details : NRG5051 is a first-in-class inhibitor of the mPTP and is designed to penetrate the brain when taken orally. It is being evaluated for the treatment of Parkinson's disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 31, 2024
Lead Product(s) : NRG5051
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : $5.0 million
Deal Type : Funding

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Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : ALS Foundation
Deal Size : Undisclosed
Deal Type : Funding
NRG Therapeutics Receives Grant from Target ALS for ALS/MND Treatments
Details : The funding will be used to support the discovery program focused on developing mPTP inhibitors as novel treatments for amyotrophic lateral sclerosis.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 05, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : ALS Foundation
Deal Size : Undisclosed
Deal Type : Funding

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Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : $0.5 million
Deal Type : Funding
Details : The funding will support NRG's lead drug discovery programme and the development of a novel treatment for Parkinson’s. NRG has discovered novel second-generation, mPTP inhibitors that are brain penetrant, for use in the treatment of chronic neurodegene...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
February 22, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : $0.5 million
Deal Type : Funding

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Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Omega Funds
Deal Size : $19.0 million
Deal Type : Series A Financing
Details : The Series A proceeds will be used to advance the company's potential first-in-class brain-penetrant small molecules through IND-enabling studies.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 09, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Omega Funds
Deal Size : $19.0 million
Deal Type : Series A Financing

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Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Innovate Biopharmaceuticals
Deal Size : $3.9 million
Deal Type : Funding
Details : The funding will support the NRG pipeline of brain-penetrant small molecule inhibitors of the mitochondrial permeability transition pore (mPTP) with potential as first-in-class treatments for Parkinson's disease (PD) and motor neuron disease (MND).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
May 30, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Innovate Biopharmaceuticals
Deal Size : $3.9 million
Deal Type : Funding
