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Find Clinical Drug Pipeline Developments & Deals for Nitric Oxide
Nitric Oxide is a guanylate cyclase activator, its novel nasal spray formulation is being evaluated for the treatment of recurrent acute rhinosinusitis.
UNO (nitric oxide) is a potent molecule, naturally synthesized in the human body. It is being evaluated in phase 1 clinical trials for advanced, relapsed or refractory unresectable, primary or metastatic cutaneous and subcutaneous solid tumors.
eNOfit is a miniaturized, portable inhaled nitric oxide (iNO) generator and delivery system for the ambulatory treatment of patients suffering from pulmonary hypertension (PH) associated with Interstitial Lung Disease (ILD).
INOmax® EVOLVE™ DS delivery system has been cleared by the U.S. Food and Drug Administration for the delivery of INOmax® (nitric oxide) gas, for inhalation, for the treating neonatal patients with hypoxic respiratory failure
The financing will be used to support the ongoing commercial launch of LungFit PH (nitric oxide) and advance clinical development of the LungFit platform. The Company has received FDA approval for LungFit PH for persistent pulmonary hypertension of the newborn.
iNOPulse (nitric oxide) enters the smooth muscle cells and activates a chemical, sGC in these cells, which produces another substance called cyclic guanosine monophosphate, that causes the smooth muscle cells to relax (vasodilation) in fibrotic interstitial lung disease.
iNOPulse (nitric oxide) enters the smooth muscle cells and activates a chemical, sGC in these cells, which produces another substance called cyclic guanosine monophosphate, that causes the smooth muscle cells to relax (vasodilation) in fibrotic interstitial lung disease.
The proceeds will be used to complete REBUILD Phase 3 study of INOpulse delivery system for the treatment of PH-ILD. The INOpulse delivery system was designed to deliver nitric oxide in a targeted fashion allowing it to act primarily on the well-functioning part of the lung.
iNOPulse (nitric oxide) enters the smooth muscle cells, it directly activates a chemical called sGC in these cells. sGC produces another substance called cyclic guanosine monophosphate. Cyclic GMP then causes the smooth muscle cells to relax, which in turn causes vasodilation.
Nitric oxide at ultra-high concentrations has been reported to show anticancer properties and to potentially serve as a chemosensitizer and radiotherapy enhancer.
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