Drugs in Dev.
Neurology
Preclinical
Belgium 
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Lead Product(s) : AGT100216
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Eli Lilly
Deal Size : $18.5 million
Deal Type : Series A Financing
Augustine Therapeutics Raises €17 Million in Series A for Neurological Lead Candidate
Details : The proceeds from the financing will be used to advance Augustine’s lead candidate, AGT100216, into early-stage clinical trials for the treatment of CMT and CIPN.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 26, 2024
Lead Product(s) : AGT100216
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Eli Lilly
Deal Size : $18.5 million
Deal Type : Series A Financing

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Lead Product(s) : CFTX-1554
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Confo Therapeutics Expands Patent Estate for ConfoBody®-Based GPCR Screening Platform
Details : The newly added patent cover Confo’s well-established small molecule screening capabilities, which led to the discovery of CFTX-1554 designed to address peripheral neuropathic pain while avoiding centrally mediated side effects, such as addiction and s...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 15, 2021
Lead Product(s) : CFTX-1554
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ReS3-T
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : National Institute of Neurological Disorders and Stroke
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The ReS3-T program is the result of a collaboration with KU Leuven’s Centre for Drug Design and Discovery (CD3). ReS3-T acts via a novel proprietary target, Pde6δ, to control neuronal activity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 04, 2021
Lead Product(s) : ReS3-T
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : National Institute of Neurological Disorders and Stroke
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : UCB Pharma S.A
Deal Size : Undisclosed
Deal Type : Acquisition
UCB Acquires Handl Therapeutics BV
Details : Acquisition of Handl Therapeutics BV augments UCB’s existing early gene therapy pipeline with two research programs, a proprietary adeno-associated virus (AAV) capsid technology platform and capabilities.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 12, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : UCB Pharma S.A
Deal Size : Undisclosed
Deal Type : Acquisition

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Lead Product(s) : CFTX-1554
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Confo has applied its proprietary, fragment-based drug discovery and structure-guided drug design technologies to identify CFTX-1554, a novel inhibitor of angiotensin II type 2 receptor, or AT2R, a clinically validated target for the treatment of neuropa...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 15, 2020
Lead Product(s) : CFTX-1554
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
