[{"orgOrder":0,"company":"Axon Neuroscience","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CYPRUS","productType":"Vaccine","year":"2015","type":"Inapplicable","leadProduct":"AADvac1","moa":"Tau aggregation","graph1":"Neurology","graph2":"Phase II","graph3":"Axon Neuroscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Axon Neuroscience \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Axon Neuroscience \/ Undisclosed"},{"orgOrder":0,"company":"Axon Neuroscience","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CYPRUS","productType":"Vaccine","year":"2013","type":"Inapplicable","leadProduct":"AADvac1","moa":"Tau aggregation","graph1":"Neurology","graph2":"Phase II","graph3":"Axon Neuroscience","amount2":0,"highestDevelopmentShortName":"Ph 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II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Axon Neuroscience \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Axon Neuroscience \/ Undisclosed"},{"orgOrder":0,"company":"Axon Neuroscience","sponsor":"University of California, San Francisco | Massachusetts General Hospital | Alzheimer's Therapeutic Research Institute | Alzheimer's Clinical Trials Consortium | National Institute on Aging","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CYPRUS","productType":"Vaccine","year":"2025","type":"Inapplicable","leadProduct":"AADvac1","moa":"Tau aggregation","graph1":"Neurology","graph2":"Phase II","graph3":"Axon Neuroscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Axon Neuroscience \/ University of California, San Francisco | Massachusetts General Hospital | Alzheimer's Therapeutic Research Institute | Alzheimer's Clinical Trials Consortium | National Institute on Aging","highestDevelopmentStatusID":"8","companyTruncated":"Axon Neuroscience \/ University of California, San Francisco | Massachusetts General Hospital | Alzheimer's Therapeutic Research Institute | Alzheimer's Clinical Trials Consortium | National Institute on Aging"},{"orgOrder":0,"company":"Axon Neuroscience","sponsor":"National Institute on Aging | Alzheimer's Therapeutic Research Institute | University of Southern California | Massachusetts General Hospital | University of California, San Diego | Alzheimer's Clinical Trials Consortium | Adam Boxer","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CYPRUS","productType":"Vaccine","year":"2025","type":"Inapplicable","leadProduct":"AADvac1","moa":"Tau aggregation","graph1":"Neurology","graph2":"Phase II","graph3":"Axon Neuroscience","amount2":0,"highestDevelopmentShortName":"Ph 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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Lead Product(s) : AADvac1

                          Therapeutic Area : Neurology

                          Study Phase : Phase II

                          Sponsor : National Institute on Aging | Alzheimer's Therapeutic Research Institute | University of Southern California | Massachusetts General Hospital | University of California, San Diego | Alzheimer's Clinical Trials Consortium | Adam Boxer

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : AADvac1 is a Vaccine drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Supranuclear Palsy, Progressive.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 16, 2025

                          Lead Product(s) : AADvac1

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : National Institute on Aging | Alzheimer's Therapeutic Research Institute | University of Southern California | Massachusetts General Hospital | University of California, San Diego | Alzheimer's Clinical Trials Consortium | Adam Boxer

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Lead Product(s) : AADvac1

                          Therapeutic Area : Neurology

                          Study Phase : Phase II

                          Sponsor : University of California, San Francisco | Massachusetts General Hospital | Alzheimer's Therapeutic Research Institute | Alzheimer's Clinical Trials Consortium | National Institute on Aging

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : AADvac1 is a Vaccine drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Alzheimer Disease.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          September 11, 2025

                          Lead Product(s) : AADvac1

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : University of California, San Francisco | Massachusetts General Hospital | Alzheimer's Therapeutic Research Institute | Alzheimer's Clinical Trials Consortium | National Institute on Aging

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : Axon is developing AADvac1 as a vaccine with the potential to halt the progression of tau pathology in Alzheimer's disease. AADvac1 is currently the most clinically-advanced tau immonotherapy in development.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          November 01, 2021

                          Lead Product(s) : AADvac1

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : A highly significant impact on neurodegeneration was shown on brain proteins in plasma - Neurofilament Light Chain, and CSF - Tau and p-Tau, and Diffusion Tensor Imaging.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          April 03, 2020

                          Lead Product(s) : AADvac1

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : AADvac1 is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Alzheimer Disease.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 19, 2015

                          Lead Product(s) : AADvac1

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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