

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Leerink Partners
Deal Size : $228.5 million
Deal Type : Public Offering
LB Pharmaceuticals eyes $228M in IPO cash
Details : LB Pharma plans to use the proceeds to advance its oral schizophrenia candidate LB-102, a modified version of amisulpride, a dopamine inhibitor.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 08, 2025
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Leerink Partners
Deal Size : $228.5 million
Deal Type : Public Offering

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Segal Trials Leads Phase 2 Schizophrenia Trial of LB-102 Toward Primary Endpoint
Details : LB-102 is a modified version of amisulpride, a dopamine inhibitor, small molecule drug candidate. It is being evaluated for the treatment of adult patients with acute schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 22, 2025
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
LB Pharma's Twist on Old Sanofi Drug Passes Schizophrenia Test, Teeing up Phase 3 Push
Details : LB-102 is a modified version of amisulpride, a dopamine inhibitor, small molecule drug candidate. It is being evaluated for the treatment of adult patients with acute schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 08, 2025
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : $75.0 million
Deal Type : Series C Financing
LB Pharmaceuticals Closes $75M Series C as it Begins Ph II Schizophrenia Trial
Details : The net proceeds from the proposed financed will focus on the development of LB-102, which is an N-methylated analogue of amisulpride under development to treat schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 24, 2024
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : $75.0 million
Deal Type : Series C Financing

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
LB Announces Publication of Phase 1 Clinical Study of LB-102
Details : LB-102, a more lipophilic version of amisulpride, was designed to improve on amisulpride’s notoriously poor membrane (BBB) permeability while matching amisulpride’s binding affinity to the D2/D3 and 5HT7 receptors (critical to the treatment of schizo...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 19, 2022
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LB-102, or N-methyl amisulpride, is a patented derivative of amisulpride, a dopamine/5-HT7 antagonist successfully used to treat schizophrenia in Europe for decades.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 04, 2021
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : $10.0 million
Deal Type : Financing
LB Pharmaceuticals Inc Secures $10.0 Million in Additional Financing
Details : Proceeds to enable the Company’s continued clinical development of LB-102 for the treatment of schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 25, 2020
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : $10.0 million
Deal Type : Financing

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
LB Pharmaceuticals Inc Announces Results of LB-102 Phase 1 First-in-Human Clinical Study
Details : LB-102 was well-tolerated up to 150 mg/day. Plasma concentrations of LB-102 were ~2.5 times greater than published values of amisulpride at the same dose, suggesting LB-102 could be dosed substantially lower than amisulpride.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 14, 2020
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The ongoing study aims to evaluate the safety, tolerability, and pharmacokinetics/pharmacodynamics of LB-102 in healthy volunteers.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 22, 2020
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
