
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RedHill Advances Crohn’s Program Following Positive RHB-104 Phase 3 Results
Details : RHB-204 is a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin & clofazimine, It is designed to safely & effectively treat MAP+-related Crohn's disease.
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Inapplicable
March 12, 2025
Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MannKind Begins Phase 3 Trial of Clofazimine Suspension in NTM Lung Disease
Details : MNKD-101 (clofazimine) is active against both slowly growing and rapidly growing mycobacteria and most Gram-positive bacteria in vitro. Being developed for pulmonary nontuberculous mycobacteria.
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Inapplicable
October 30, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MannKind Receives PMDA Clearance for Phase 3 Trial of Clofazimine in NTM Lung Disease
Details : MNKD-101 (clofazimine) is active against both slowly growing and rapidly growing mycobacteria and most Gram-positive bacteria in vitro, being developed for pulmonary nontuberculous mycobacteria.
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Inapplicable
September 18, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Clofazimine is a Antibiotic drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of MAC Lung Disease.
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Inapplicable
May 17, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MannKind Receives Fast Track Designation for Clofazimine Inhalation for NTM Lung Disease
Details : MNKD-101 (clofazimine) has antimicrobial and anti-inflammatory effects, active against mycobacteria and Gram-positive bacteria, and is being developed for pulmonary nontuberculous mycobacteria.
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Inapplicable
May 06, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MannKind Announces IND Clearance for Phase 3 Study of Clofazimine Inhalation
Details : MNKD-101 (clofazimine) has antimicrobial and anti-inflammatory effects, active against mycobacteria and Gram-positive bacteria, and is being developed for pulmonary nontuberculous mycobacteria.
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Inapplicable
April 29, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RHB-204 (clarithromycin) is a 70s Bacterial ribosome inhibitor combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by Mycobacterium avium Complex (MAC).
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Inapplicable
May 22, 2023
Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $6.0 million
Deal Type : Public Offering
RedHill Biopharma Announces Closing of $6 Million Registered Direct Offering
Details : The Company intends to use the net proceeds for the development of RHB-204, a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by MAC.
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Undisclosed
April 03, 2023
Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $6.0 million
Deal Type : Public Offering

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Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $6.0 million
Deal Type : Public Offering
RedHill Biopharma Announces $6 Million Registered Direct Offering
Details : The net proceeds will be used in the development of RHB-204, a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by Mycobacterium avium...
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Undisclosed
March 30, 2023
Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $6.0 million
Deal Type : Public Offering

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Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : $6.0 million
Deal Type : Private Placement
Details : RHB-204 (clarithromycin) is a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by Mycobacterium avium Complex (MAC).
Product Name : Undisclosed
Product Type : Antibiotic
Upfront Cash : Undisclosed
March 08, 2023
Lead Product(s) : Clarithromycin,Clofazimine,Rifabutin
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : $6.0 million
Deal Type : Private Placement
