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            Details:

            By utilizing MRI’s internal pro-forma revenue projections for 2023 & 2024 and comparable market transactions, MRI’s drug development pipeline including MAN-01 and companion diagnostics, are estimated to achieve a net present value.

            Lead Product(s): MAN-01

            Therapeutic Area: Ophthalmology Product Name: MAN-01

            Highest Development Status: Preclinical Product Type: Small molecule

            Recipient: Q BioMed

            Deal Size: $42.3 million Upfront Cash: Undisclosed

            Deal Type: Agreement November 14, 2022

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            MAN-19 therapeutic is a recombinant fusion protein that treats the patient, instead of targeting the virus. It is not a cure for COVID, but it strengthens a patient's blood vessels and protects them against ARDS, breathing problems, sepsis and other infections.

            Lead Product(s): MAN-19

            Therapeutic Area: Infections and Infectious Diseases Product Name: MAN-19

            Highest Development Status: Preclinical Product Type: Small molecule

            Recipient: Q BioMed

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 22, 2021

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            Platform has been awarded grants from Canada and Europe for its development of therapeutics; additional grant submitted to the STTR program administered by the U.S. National Institutes of Health.

            Lead Product(s): Undisclosed

            Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Undisclosed

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 20, 2020

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