Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ESG401,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Shanghai Escugen Biotechnology
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ESG401 is composed of a humanized anti-Trop2 IgG1 monoclonal antibody (mAb) conjugated to a topoisomerase I inhibitor SN38 via a proprietary stable covalent linker with a drug antibody ratio (DAR) of 8.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
May 06, 2023
Lead Product(s) : ESG401,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Shanghai Escugen Biotechnology
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : A166,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Sichuan Kelun-Biotech Biopharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : A166, a third-generation antibody-drug conjugate with tubulin inhibitor Duo-5 toxin, cleavable linker and site-specific K-Lock conjugation chemistry, demonstrated antitumor activity with meaningful responses in heavily pretreated subjects with HER2-posit...
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
March 05, 2022
Lead Product(s) : A166,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Sichuan Kelun-Biotech Biopharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : A166,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Sichuan Kelun Pharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : A166 is an antibody-drug conjugate (ADC) composed of an anti-HER2 antibody conjugated to Duostatin-5, a novel anti-microtubule Auristatin derivative, via a proprietary stable covalent linker.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
January 06, 2022
Lead Product(s) : A166,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Sichuan Kelun Pharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed,Inapplicable
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Navrogen
Deal Size : Undisclosed
Deal Type : Collaboration
Navrogen and Levena collaborate to Develop Antibody Drug Conjugates
Details : ADCs developed under this collaboration combine Levena’s linker and cytotoxic payload chemistry expertise along with Navrogen’s cancer-targeting antibodies.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
April 02, 2020
Lead Product(s) : Undisclosed,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Navrogen
Deal Size : Undisclosed
Deal Type : Collaboration