[{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Tabirafusp Alfa","moa":"IL-6|VEGF","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Tabirafusp Alfa","moa":"IL-6|VEGF","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"KSI-501","moa":"Undisclosed","graph1":"Rare Diseases and Disorders","graph2":"Phase I","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2024","type":"Inapplicable","leadProduct":"Tarcocimab","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2024","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2023","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2025","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2024","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Baker Bros","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2021","type":"Termination","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0.23000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0.23000000000000001,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Baker Bros","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Baker Bros"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2023","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Lonza Biologics Inc","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Agreement","leadProduct":"Tarcocimab Tedromer","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase II\/ Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Kodiak Sciences","highestDevelopmentStatusID":"9","companyTruncated":"Kodiak Sciences \/ Kodiak Sciences"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"KSI-301","moa":"VEGF-A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"KSI-301","moa":"VEGF-A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2020","type":"Inapplicable","leadProduct":"KSI-301","moa":"VEGF-A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2021","type":"Inapplicable","leadProduct":"KSI-301","moa":"VEGF-A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-biopolymer Conjugate","year":"2021","type":"Inapplicable","leadProduct":"KSI-301","moa":"VEGF-A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Undisclosed"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"AbCellera","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"CANADA","productType":"Undisclosed","year":"2020","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Rare Diseases and Disorders","graph2":"Discovery Platform","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kodiak Sciences \/ Kodiak Sciences","highestDevelopmentStatusID":"3","companyTruncated":"Kodiak Sciences \/ Kodiak Sciences"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Nona Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Partnership","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Discovery Platform","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kodiak Sciences \/ Kodiak Sciences","highestDevelopmentStatusID":"3","companyTruncated":"Kodiak Sciences \/ Kodiak Sciences"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : KSI-101 (Tabirafusp Alfa) is a Protein drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Macular Edema.

                          Product Name : KSI-101

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          May 30, 2025

                          Lead Product(s) : Tabirafusp Alfa

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : KSI-101 (Tabirafusp Alfa) is a Protein drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Macular Edema.

                          Product Name : KSI-101

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          May 25, 2025

                          Lead Product(s) : Tabirafusp Alfa

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : KSI-301 (tarcocimab tedromer) is designed to maintain potent and effective drug levels in ocular tissues for longer than existing anti-VEGF therapies. It is evaluated for diabetic retinopathy.

                          Product Name : Undisclosed

                          Product Type : Antibody-biopolymer Conjugate

                          Upfront Cash : Inapplicable

                          March 10, 2025

                          Lead Product(s) : Tarcocimab Tedromer

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : The partnership aims to advance the discovery of novel multi-target antibodies to treat ophthalmic diseases, leveraging Nona's proprietary Harbour Mice fully human antibody platform.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 09, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Discovery Platform

                          Recipient : Nona Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          05

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : Tarcocimab Tedromer is a Antibody-biopolymer Conjugate drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Wet Macular Degeneration.

                          Product Name : Undisclosed

                          Product Type : Antibody-biopolymer Conjugate

                          Upfront Cash : Inapplicable

                          August 16, 2024

                          Lead Product(s) : Tarcocimab Tedromer

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : KSI-301 (tarcocimab tedromer) maintains potent drug levels in ocular tissues longer than existing anti-VEGF therapies, currently under investigation for neovascular age-related macular degeneration.

                          Product Name : Undisclosed

                          Product Type : Antibody-biopolymer Conjugate

                          Upfront Cash : Inapplicable

                          May 13, 2024

                          Lead Product(s) : Tarcocimab Tedromer

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : Tarcocimab is a Antibody drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Diabetic Retinopathy.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          February 21, 2024

                          Lead Product(s) : Tarcocimab

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : KSI-301 (tarcocimab tedromer) is designed to maintain potent and effective drug levels in ocular tissues for longer than existing anti-VEGF therapies, which is investigated for the treatment of neovascular age-related macular degeneration and diabetic ma...

                          Product Name : Undisclosed

                          Product Type : Antibody-biopolymer Conjugate

                          Upfront Cash : Inapplicable

                          November 06, 2023

                          Lead Product(s) : Tarcocimab Tedromer

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : KSI-301 (tarcocimab tedromer) is designed to maintain potent and effective drug levels in ocular tissues for longer than existing anti-VEGF therapies, which is investigated for the treatment of neovascular age-related macular degeneration and diabetic ma...

                          Product Name : Undisclosed

                          Product Type : Antibody-biopolymer Conjugate

                          Upfront Cash : Inapplicable

                          July 24, 2023

                          Lead Product(s) : Tarcocimab Tedromer

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Pharma MES 2025
                          Not Confirmed
                          Pharma MES 2025
                          Not Confirmed

                          Details : KSI-501 is a bispecific ABC that is designed to inhibit two mechanisms implicated in vascular endothelial growth factor ("VEGF") and interleukin-6 (IL-6), a pro-inflammatory cytokine and growth factor implicated in the pathophysiology of multiple retinal...

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          April 03, 2023

                          Lead Product(s) : KSI-501

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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