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    [{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Genentech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Kadcyla","moa":"Receptor protein-tyrosine kinase erbB-2 | Tubulin","graph1":"Oncology","graph2":"Phase II","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Dana-Farber Cancer Institute \/ Genentech","highestDevelopmentStatusID":"8","companyTruncated":"Dana-Farber Cancer Institute \/ Genentech"},{"orgOrder":0,"company":"Seagen","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Tucatinib","moa":"||Receptor protein-tyrosine kinase erbB-2","graph1":"Oncology","graph2":"Approved FDF","graph3":"Seagen","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Seagen \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Seagen \/ Inapplicable"}]

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                            01

                            Seagen

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                            Seagen

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                            Lead Product(s) : Tucatinib,Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Seagen Phase 3 Trial of TUKYSA (tucatinib) in Combination with Antibody-Drug Conjugate Ado-trastuzumab Emtansi...

                            Details : TUKYSA (tucatinib) is an oral medicine that is a tyrosine kinase inhibitor of the HER2 protein and in combination with ado-trastuzumab emtansine is being developed in patients with HER2-positive metastatic or unresectable breast cancer.

                            Product Name : Tukysa

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 16, 2023

                            Lead Product(s) : Tucatinib,Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Dana-Farber Cancer Institute

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                            iPHEX India
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                            Dana-Farber Cancer Institute

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                            iPHEX India
                            Not Confirmed
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                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Genentech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            November 06, 2020

                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Genentech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Dana-Farber Cancer Institute

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                            iPHEX India
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                            Dana-Farber Cancer Institute

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                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Study Of Pembrolizumab In Combination With Trastuzumab-DM1

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 26, 2017

                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Memorial Sloan Kettering Cancer Center

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            Memorial Sloan Kettering Cancer Center

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                            iPHEX India
                            Not Confirmed
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                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Genentech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Trial of Ado-Trastuzumab Emtansine for Patients With HER2 Amplified or Mutant Cancers

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            February 05, 2016

                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Genentech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Dana-Farber Cancer Institute

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                            iPHEX India
                            Not Confirmed

                            Dana-Farber Cancer Institute

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                            iPHEX India
                            Not Confirmed
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                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Genentech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            T-DM1+Pertuzumab in Pre-OP Early-Stage HER2+ BRCA

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            December 30, 2014

                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Genentech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            The Methodist Hospital Research Institute

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                            iPHEX India
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                            The Methodist Hospital Research Institute

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                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Celgene Corporation | Novartis Pharmaceuticals Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Neoadjuvant TDM1 With Lapatinib and Abraxane Compared With Trastuzumab Plus Pertuzumab With Paclitaxel

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            February 27, 2014

                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Celgene Corporation | Novartis Pharmaceuticals Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            West German Study Group

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                            iPHEX India
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                            West German Study Group

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                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Prospective, Randomized Multicenter, Open-label Comparison of Preoperative Trastuzumab Emtansine (T-DM1) Wit...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            December 10, 2012

                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Jules Bordet Institute

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                            iPHEX India
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                            Jules Bordet Institute

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                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            HER2 Imaging Study to Identify HER2 Positive Metastatic Breast Cancer Patient Unlikely to Benefit From T-DM1

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            March 28, 2012

                            Lead Product(s) : Kadcyla

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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