Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Stemline Therapeutics
Deal Size : $570.0 million
Deal Type : Licensing Agreement
Menarini & Insilico Medicine Sign Global License for AI-Discovered Oncology Asset
Details : Under the licensing agreement, Stemline will hold the global rights to develop and commercialize a preclinical small molecule targeting high unmet needs in oncology.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : $20.0 million
January 10, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Stemline Therapeutics
Deal Size : $570.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Stemline Therapeutics
Deal Size : $512.0 million
Deal Type : Licensing Agreement
Menarini Group Signs Exclusive License for KAT6 Inhibitor for Breast Cancer
Details : Stemline will have global rights to develop a novel KAT6A inhibitor designed using Insilico’s AI platform, targeting hormone-sensitive cancers and other oncology indications.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $12.0 million
April 01, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Stemline Therapeutics
Deal Size : $512.0 million
Deal Type : Licensing Agreement
Lead Product(s) : ISM3091
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Exelixis
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the agreement, Insilico granted Exelixis an exclusive, worldwide license to develop and commercialize ISM3091, a best-in-class small molecule inhibitor of USP1, as a synthetic lethal target in the context of BRCA-mutated tumors, and other USP1-targ...
Product Name : ISM3091
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 09, 2023
Lead Product(s) : ISM3091
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Exelixis
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Preclinical candidate targeting methionine adenosyltransferase 2A (MAT2A) from AI-designed molecules for the treatment of methylthioadenosine phosphorylase (MTAP)-deleted cancers.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 05, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ISM025
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Insilico's PCC molecule, ISM025 demonstrated potential when targeted against a broad range of tumor lineages with HRD backgrounds. In vitro data showed potent anti-proliferation activity of the compound in BRCA-mutant tumor cells with excellent selectivi...
Product Name : ISM025
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 13, 2022
Lead Product(s) : ISM025
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The collaboration will combine Insilico's Pharma.AI platform to advance de novo small molecule design and generation with EQRx's clinical development and commercialization expertise.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
March 24, 2022