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Undisclosed"},{"orgOrder":0,"company":"INmune Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"INKmune","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"INmune Bio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"INmune Bio \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"INmune Bio \/ Undisclosed"},{"orgOrder":0,"company":"INmune Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"INKmune","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"INmune 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Undisclosed"},{"orgOrder":0,"company":"INmune Bio","sponsor":"Cell and Gene Therapy Catapult","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"UNITED KINGDOM","productType":"Cell & Gene Therapy","year":"2025","type":"Partnership","leadProduct":"Umbilical Cord Derived Mesenchymal Stromal Cell","moa":"Undisclosed","graph1":"Rare Diseases and Disorders","graph2":"Phase II","graph3":"INmune Bio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"INmune Bio \/ INmune Bio","highestDevelopmentStatusID":"8","companyTruncated":"INmune Bio \/ INmune Bio"},{"orgOrder":0,"company":"INmune Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"Umbilical Cord Derived Mesenchymal Stromal Cell","moa":"Undisclosed","graph1":"Rare Diseases and Disorders","graph2":"Phase III","graph3":"INmune Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"INmune Bio \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"INmune Bio \/ Undisclosed"},{"orgOrder":0,"company":"INmune Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"INmune Bio","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"INmune Bio \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"INmune Bio \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals by INmune Bio

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                          Top Deals by Deal Size (USD bn)

                          01

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : XPro1595 (pegipanermin), a subcutaneous injection, showed reduced amyloid and improved behavior in a TBI Alzheimer’s animal model, supported by the U.S. Department of Defense.

                          Product Name : XPro1595

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          June 10, 2025

                          Lead Product(s) : Pegipanermin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Sponsor : Virginia Commonwealth University

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The collaboration will focus on scaling production of CORDStrom, a proprietary pooled, allogeneic, human umbilical cord-derived mesenchymal Stromal/Stem cell (hucMSCs) platform, for RDEB.

                          Product Name : CORDStrom

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Undisclosed

                          April 14, 2025

                          Lead Product(s) : Umbilical Cord Derived Mesenchymal Stromal Cell

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase II

                          Recipient : Cell and Gene Therapy Catapult

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : INKmune is an NK cell targeted therapy, designed to improve the function of the patient’s own NK cells. It is under development for the treatment of patients with mCRPC.

                          Product Name : INKmune

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          February 12, 2025

                          Lead Product(s) : INKmune

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : CORDStrom is an aseptic, allogeneic, pooled human umbilical cord -derived mesenchymal stromal cellsbeing investigated for recessive dystrophic epidermolysis bullosa.

                          Product Name : CORDStrom

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          February 10, 2025

                          Lead Product(s) : Umbilical Cord Derived Mesenchymal Stromal Cell

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : INKmune is an NK cell targeted therapy, designed to improve the function of the patient’s own NK cells. It is under development for the treatment of patients with mCRPC.

                          Product Name : INKmune

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          January 28, 2025

                          Lead Product(s) : INKmune

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The partnership aims to advance INmune Bio’s mid-stage product XPro1595 (Pegipanerm), which is being evaluated for the treatment of Alzheimer’s disease.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          December 04, 2024

                          Lead Product(s) : Pegipanermin

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : OmniScience

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : XPro1595 (pegipanermin) is a next-generation selective TNF inhibitor that is currently in clinical trials. It neutralizes soluble TNF (sTNF), without affecting tmTNF or TNF receptors.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          November 13, 2024

                          Lead Product(s) : Pegipanermin

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : XPro1595 (pegipanermin) is a next-generation selective TNF inhibitor which acts by neutralizing soluble TNF (sTNF), without affecting trans-membrane TNF (tmTNF) or TNF receptors.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 30, 2024

                          Lead Product(s) : Pegipanermin

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : INKmune is an NK cell targeted therapy, designed to improve the function of the patient’s own NK cells. It is under development for the treatment of metastatic castration-resistant prostate cancer.

                          Product Name : INKmune

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          September 26, 2024

                          Lead Product(s) : INKmune

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Xpro1595 (pegipanermin) is a TNF inhibitor that is currently in clinical trials in patients with neurologic disease by decreasing neuroinflammation and restoring innate immune cell function.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 17, 2024

                          Lead Product(s) : Pegipanermin

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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