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Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Eiger BioPharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Atea Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Bemnifosbuvir","moa":"||RNA-dependent DNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Atea Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Atea Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Atea Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Bioxytran","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Galactomannan","moa":"Galectin-1","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Bioxytran","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet, Chewable","sponsorNew":"Bioxytran \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Bioxytran \/ Inapplicable"},{"orgOrder":0,"company":"Moderna Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2025","type":"Inapplicable","leadProduct":"COVID-19 Vaccine, mRNA","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Moderna Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Pre-Filled Injection","sponsorNew":"Moderna Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Moderna Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Lyra Therapeutics","sponsor":"H.C. Wainwright & Co","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Steroid","year":"2025","type":"Public Offering","leadProduct":"Mometasone Furoate","moa":"Glucocorticoid receptor","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Lyra Therapeutics","amount2":0.02,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.02,"dosageForm":"Undisclosed","sponsorNew":"Lyra Therapeutics \/ H.C. Wainwright & Co","highestDevelopmentStatusID":"10","companyTruncated":"Lyra Therapeutics \/ H.C. Wainwright & Co"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            Lyra Therapeutics

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                            Lyra Therapeutics

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                            Lead Product(s) : Mometasone Furoate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : H.C. Wainwright & Co

                            Deal Size : $15.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Lyra Announces Up to $15 Million Registered Direct Offering and Private Placement

                            Details : Lyra will use the financing to advance its for LYR-210 canditate, an investigational product candidate for the treatment of chronic rhinosinusitis.

                            Product Name : LYR-210

                            Product Type : Steroid

                            Upfront Cash : Undisclosed

                            June 27, 2025

                            Lead Product(s) : Mometasone Furoate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : H.C. Wainwright & Co

                            Deal Size : $15.0 million

                            Deal Type : Public Offering

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                            02

                            Vir Biotechnology

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                            Pharmex
                            Not Confirmed

                            Vir Biotechnology

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                            Pharmex
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                            Lead Product(s) : Tobevibart,Elebsiran

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vir Biotech Enrolls First Patient in Phase 3 ECLIPSE Hepatitis Delta Study

                            Details : VIR-3434 (tobevibart) is a subcutaneous antibody designed to block entry of hepatitis B and hepatitis delta viruses. It is being evaluated in combination with elebsiran for chronic hepatitis D.

                            Product Name : VIR-3434

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 13, 2025

                            Lead Product(s) : Tobevibart,Elebsiran

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Merck & Co

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                            Pharmex
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                            Merck & Co

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                            Lead Product(s) : Islatravir,Doravirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck’s DOR/ISL Two-Drug Regimen Shows 48-Week HIV-1 Viral Suppression in Trials

                            Details : MK-8591A is a combination of islatravir and Doravirine which are being investigated as non-nucleoside reverse transcriptase translocation inhibitor of HIV-1.

                            Product Name : MK-8591A

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 12, 2025

                            Lead Product(s) : Islatravir,Doravirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Precigen

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                            Pharmex
                            Not Confirmed

                            Precigen

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                            Pharmex
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                            Lead Product(s) : Zopapogene Imadenovec

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Grants Priority Review to Precigen’s PRGN-2012 for Recurrent Papillomatosis

                            Details : PRGN-2012 (zopapogene imadenovec) is a HPV 6/11-specific T-cell response inducer, is an off the shelf OTS adenoVerse gene therapy vaccine. It is in trial for current respiratory papillomatosis.

                            Product Name : PRGN-2012

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 25, 2025

                            Lead Product(s) : Zopapogene Imadenovec

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Moderna Therapeutics

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                            Pharmex
                            Not Confirmed

                            Moderna Therapeutics

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                            Pharmex
                            Not Confirmed
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                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Moderna Norovirus Vaccine Trial on Hold by US FDA Over Neurological Side Effect

                            Details : mRNA-1403 is an mRNA vaccine which is currently being evaluated to prevent moderate to severe acute gastroenteritis caused by norovirus.

                            Product Name : mRNA-1403

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 14, 2025

                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Precigen

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                            Pharmex
                            Not Confirmed

                            Precigen

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                            Pharmex
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                            Lead Product(s) : Zopapogene Imadenovec

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Precigen Submits BLA with Request for Priority Review for PRGN-2012

                            Details : PRGN-2012 a new molecular entity, a HPV 6/11-specific T-cell response inducer, is an off the shelf OTS AdenoVerse gene therapy vaccine. It is in developmnet for recurrent respiratory papillomatosis.

                            Product Name : PRGN-2012

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 30, 2024

                            Lead Product(s) : Zopapogene Imadenovec

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Merck & Co

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                            Pharmex
                            Not Confirmed

                            Merck & Co

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                            Pharmex
                            Not Confirmed
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                            Lead Product(s) : Islatravir,Doravirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck Announces Topline Results From Phase 3 Trials Of Doravirine/Islatravir Regimen

                            Details : MK-8591A is a combination of islatravir and Doravirine which are being investigated as non-nucleoside reverse transcriptase translocation inhibitor of HIV-1.

                            Product Name : MK-8591A

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 19, 2024

                            Lead Product(s) : Islatravir,Doravirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            MicuRx Pharmaceuticals

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                            Pharmex
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                            MicuRx Pharmaceuticals

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                            Lead Product(s) : Contezolid

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MicuRx: Successfully Completes Phase III Clinical Trial of MRX-4 for Injection in China

                            Details : MRX-4 (contezolid) is a novel oxazolidinone-class antibacterial drug. Currently, it is being investigated in the late-stage clinical trial studies for the treatment of cSSTI in China.

                            Product Name : MRX-1

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            November 29, 2024

                            Lead Product(s) : Contezolid

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            PaxMedica

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                            Pharmex
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                            PaxMedica

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                            Lead Product(s) : Suramin

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PaxMedica Achieves Key Milestone in PAX-101 Development

                            Details : PAX-101, if approved by the FDA will be the potential first and only intravenous form of suramin for the treatment of Stage 1 Human African Trypanosomiasis, caused by Trypanosoma brucei rhodesiense.

                            Product Name : PAX-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 04, 2024

                            Lead Product(s) : Suramin

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Moderna Therapeutics

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                            Pharmex
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                            Moderna Therapeutics

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                            Pharmex
                            Not Confirmed
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                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            UK’s First Norovirus mRNA Vaccine Trial Launched

                            Details : mRNA-1403 is an mRNA vaccine which is currently being evaluated to prevent moderate to severe acute gastroenteritis caused by norovirus.

                            Product Name : mRNA-1403

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            October 24, 2024

                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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