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    [{"orgOrder":0,"company":"Imugene","sponsor":"Precision BioSciences","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2024","type":"Licensing Agreement","leadProduct":"Azercabtagene Zapreleucel","moa":"CD19","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Imugene","amount2":0.23000000000000001,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.66000000000000003,"dosageForm":"Infusion","sponsorNew":"Imugene \/ Imugene","highestDevelopmentStatusID":"7","companyTruncated":"Imugene \/ Imugene"},{"orgOrder":0,"company":"Imugene","sponsor":"Kincell Bio","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2024","type":"Agreement","leadProduct":"Azercabtagene Zapreleucel","moa":"||CD19","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Imugene","amount2":0,"highestDevelopmentShortName":"Ph 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Hope"},{"orgOrder":0,"company":"Imugene","sponsor":"RenovoRx","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Discovery Platform","graph3":"Imugene","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Imugene \/ Imugene","highestDevelopmentStatusID":"3","companyTruncated":"Imugene \/ Imugene"}]

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                            01

                            Imugene

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                            Lead Product(s) : Azercabtagene Zapreleucel

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Precision BioSciences

                            Deal Size : $227.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Precision Receives $13M in Proceeds from Imugene Convertible Notes

                            Details : Imugene assumed global rights to azer-cel for cancer, the ongoing clinical execution for PBCAR0191 (azercabtagene zapreleucel) in LBCL patients who have relapsed following autologous CAR T treatment.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : $21.0 million

                            September 03, 2024

                            Lead Product(s) : Azercabtagene Zapreleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Precision BioSciences

                            Deal Size : $227.0 million

                            Deal Type : Licensing Agreement

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                            02

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                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Three Complete Responses in Azer-Cel Allogeneic CD19 CAR T Phase 1b Trial for Blood Cancer

                            Details : Azercabtagene Zapreleucel (azer-cel), an allogeneic CD19 CAR T cell therapy being investigated relapsed/refractory diffuse large B cell lymphoma.

                            Product Name : Azer-Cel

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            September 03, 2024

                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Kincell Bio

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Imugene and Kincell Announce Strategic Manufacturing and Process Development Partnership

                            Details : Under the agreement, Kincell will manufacture Imugene’s Azer-cel (azercabtagene zapreleucel), an off-the-shelf (allogeneic) cell therapy CAR T drug, to support ongoing clinical trials.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            April 16, 2024

                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Kincell Bio

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Lead Product(s) : CF33-CD19,Blinatumomab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase 1 onCARlytics Solid Tumour Trial Advances to Combination Arm Treatment

                            Details : onCARlytics (CF33-CD19) is a novel CD19 oncolytic virotherapy drug candidate, which is being evaluated for the treatment of patients with advanced solid tumors.

                            Product Name : onCARlytics

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 11, 2024

                            Lead Product(s) : CF33-CD19,Blinatumomab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : MaxCyte

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            MaxCyte Signs License with Imugene To Advance Cancer Immunotherapy Programs

                            Details : Imugene has obtained commercial rights to use MaxCyte’s technology and ExPERT platform to support azer-cel, a potential allogeneic CD19 CAR T product candidate for blood cancer treatment.

                            Product Name : Azer-Cel

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            January 23, 2024

                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : MaxCyte

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            06

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                            Lead Product(s) : Azercabtagene Zapreleucel,Efineptakin Alpha

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : NeoImmuneTech

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            NeoImmuneTech and Imugene Enter into Strategic Research Collaboration to Improve Cancer Treatments

                            Details : The collaboration aims to evaluate Imugene's allogeneic CAR T, azer-cel, in combination with NIT's proprietary immune T cell amplifier "Fc-fused recombinant human interleukin-7", NT-I7, for the treatment of cancer.

                            Product Name : Azer-Cel

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            December 11, 2023

                            Lead Product(s) : Azercabtagene Zapreleucel,Efineptakin Alpha

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : NeoImmuneTech

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Imugene

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                            Lead Product(s) : CF33-CD19

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of onCARlytics (CF33-CD19) in Combination With Blinatumomab in Adults With Advanced or Metastatic Soli...

                            Details : CF33-CD19 is a Other Large Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 02, 2023

                            Lead Product(s) : CF33-CD19

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Precision BioSciences

                            Deal Size : $662.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Precision BioSciences Completes Strategic Transaction with Imugene for Azer-Cel in Cancer

                            Details : Imugene gains global rights to PBCAR0191 (azercabtagene zapreleucel), Precision’s lead allogeneic CAR T candidate, for cancer. Imugene will assume ongoing trial for azer-cel in the large B-cell lymphoma and has an option to develop up to three other ca...

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : $29.0 million

                            August 15, 2023

                            Lead Product(s) : Azercabtagene Zapreleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Precision BioSciences

                            Deal Size : $662.0 million

                            Deal Type : Licensing Agreement

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Recipient : RenovoRx

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            RenovoRx and Imugene Announce Collaboration to Deliver Oncolytic Virus Therapy Using Proprietary Trans-Arteria...

                            Details : The collaboration aims to optimize the delivery of Imugene’s oncolytic virus therapy with RenovoRx’s TAMP (Trans-Arterial Micro-Perfusion) therapy platform for the treatment of difficult-to-access tumors.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            July 20, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Recipient : RenovoRx

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Imugene

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                            Imugene

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                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : CF33-CD19,Blinatumomab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            FDA Clears Imugene IND To Commence onCARlytics First-In-Class Clinical Study

                            Details : onCARlytics (CF33-CD19, HOV4) is a live, attenuated oncolytic orthopox (vaccinia) virus engineered to encode a truncated human CD19 transgene, resulting in expression of de novo CD19 at the tumour cell surface before virus-mediated tumour cell lysis.

                            Product Name : onCARlytics

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 19, 2023

                            Lead Product(s) : CF33-CD19,Blinatumomab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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