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Find Clinical Drug Pipeline Developments & Deals for HC-5404

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                          01

                          COMPAMED
                          Not Confirmed
                          COMPAMED
                          Not Confirmed

                          Details : The collaboration aims to advance HC-5404 for PERK in renal cell carcinoma (RCC).

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          November 04, 2025

                          Lead Product(s) : HC-5404

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Aveo Oncology

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          COMPAMED
                          Not Confirmed
                          COMPAMED
                          Not Confirmed

                          Details : HC-5404 is a first-in-class, first-in-human selective and potent PKR-like endoplasmic reticulum kinase (PERK) inhibitor. Itis being evaluated in phase 1 clinical trials for the treatment of solid tumors.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 27, 2023

                          Lead Product(s) : HC-5404

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          COMPAMED
                          Not Confirmed
                          COMPAMED
                          Not Confirmed

                          Details : As reported in June 2021, the company initiated a first-in-human, Phase 1a clinical trial for HC-5404-FU in select solid tumors, filed their Investigational New Drug (IND) application and received FDA authorization to begin clinical studies in late 2020.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 08, 2021

                          Lead Product(s) : HC-5404

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          COMPAMED
                          Not Confirmed
                          COMPAMED
                          Not Confirmed

                          Details : The primary endpoints are to establish HC-5404-FU’s Maximum Tolerated Dose (MTD) and to monitor its safety and tolerability in patients with selected, advanced solid tumors.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 10, 2021

                          Lead Product(s) : HC-5404

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Labcorp Drug Development

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          COMPAMED
                          Not Confirmed
                          COMPAMED
                          Not Confirmed

                          Details : HC-5404-FU is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Renal Cell.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          April 08, 2021

                          Lead Product(s) : HC-5404

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Covance

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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