
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : HC-5404
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Aveo Oncology
Deal Size : Undisclosed
Deal Type : Collaboration
Aveo Oncology and LG Chem's HiberCell sign exclusive agreement for new compound
Details : The collaboration aims to advance HC-5404 for PERK in renal cell carcinoma (RCC).
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 04, 2025
Lead Product(s) : HC-5404
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Aveo Oncology
Deal Size : Undisclosed
Deal Type : Collaboration

Details : HC-5404 is a first-in-class, first-in-human selective and potent PKR-like endoplasmic reticulum kinase (PERK) inhibitor. Itis being evaluated in phase 1 clinical trials for the treatment of solid tumors.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 27, 2023

Details : As reported in June 2021, the company initiated a first-in-human, Phase 1a clinical trial for HC-5404-FU in select solid tumors, filed their Investigational New Drug (IND) application and received FDA authorization to begin clinical studies in late 2020.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 08, 2021

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Lead Product(s) : HC-5404
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Labcorp Drug Development
Deal Size : Inapplicable
Deal Type : Inapplicable
HiberCell Initiates Phase 1a Clinical Trial of HC-5404-FU, an ER Stress Modulator
Details : The primary endpoints are to establish HC-5404-FU’s Maximum Tolerated Dose (MTD) and to monitor its safety and tolerability in patients with selected, advanced solid tumors.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 10, 2021
Lead Product(s) : HC-5404
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Labcorp Drug Development
Deal Size : Inapplicable
Deal Type : Inapplicable

A Study of HC-5404-FU to Establish the Maximum Tolerated Dose (MTD)
Details : HC-5404-FU is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Renal Cell.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
April 08, 2021

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