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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
Hemlibra (emicizumab-kxwh) is bispecific monoclonal antibody created with Chugai’s proprietary antibody engineering technologies. The drug is designed to bind factor IXa and factor X.
Vonvendi is a recombinant von Willebrand factor(rVWF)indicated for use in adults (age 18 and older) diagnosed with von Willebrand disease(VWD),is available as a lyophilized powder in single-dose vials containing nominally 650 or 1300 international units.
Lead Product(s):
Recombinant Von Willebrand Factor
TAKHZYRO® (Lanadelumab-flyo) Injection is a fully human monoclonal antibody that specifically binds and decreases plasma kallikrein and is indicated for routine prevention of recurrent attacks of HAE in patients aged 12 years and older.
CRYSVITA (burosumab) was created and developed by Kyowa Kirin and is a recombinant fully human monoclonal antibody that binds to and inhibits the activity of FGF23.2 CRYSVITA blocks the action of FGF23, restoring phosphate homeostasis.
Hemlibra (Emicizumab-kxwh) is a bispecific monoclonal antibody created with Chugai’s proprietary antibody engineering technologies. The drug is designed to bind factor IXa and factor X. Hemlibra provides the cofactor function of factor VIII in people with hemophilia A.
TAKHZYRO is a fully human monoclonal antibody that specifically binds and decreases plasma kallikrein and is indicated for routine prevention of recurrent attacks of HAE in patients aged 12 years and older. TAKHZYRO is formulated for subcutaneous administration.
The approval is primarily based on results of global Phase 3 HELP Study™ and the Phase 3 HELP Study Open-label Extension (OLE), in addition to results of a Phase 3 study evaluating the efficacy and safety of TAKHZYRO in Japanese patients.
The MHLW approved IZCARGO, a recombinant fusion protein of an antibody against the human transferrin receptor for the treatment of MPS II based on results from clinical trials conducted in Japan and Brazil.
IZCARGO® (formerly known as JR-141), is a recombinant iduronate-2-sulfatase enzyme replacement therapy (ERT) that relies on J-Brain Cargo®, a proprietary technology developed by JCR, to deliver therapeutics across the blood-brain barrier (BBB).
VONVENDI (Recombinant Von Willebrand Factor) is the First and Only Treatment Approved for Routine Prophylaxis to Reduce the Frequency of Bleeding Episodes in Adults Living with Severe Type 3 VWD Receiving On-Demand Therapy.
Lead Product(s):
Recombinant Von Willebrand Factor
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