[{"orgOrder":0,"company":"Curis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Fimepinostat","moa":"Histone deacetylase | PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | PI3-kinase p110-delta subunit||PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | Histone deacetylase | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase I","graph3":"Curis","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Curis \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Curis \/ Undisclosed"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Curis","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Fimepinostat","moa":"Histone deacetylase | PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | PI3-kinase p110-delta subunit||PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | Histone deacetylase | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase I","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Dana-Farber Cancer Institute \/ Curis","highestDevelopmentStatusID":"6","companyTruncated":"Dana-Farber Cancer Institute \/ Curis"},{"orgOrder":0,"company":"Curis","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Fimepinostat","moa":"Histone deacetylase | PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | PI3-kinase p110-delta subunit||PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | Histone deacetylase | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase II","graph3":"Curis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Curis \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Curis \/ Undisclosed"},{"orgOrder":0,"company":"Curis","sponsor":"Leukemia and Lymphoma Society","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Fimepinostat","moa":"Histone deacetylase | PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase I","graph3":"Curis","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Curis \/ Leukemia and Lymphoma Society","highestDevelopmentStatusID":"6","companyTruncated":"Curis \/ Leukemia and Lymphoma Society"},{"orgOrder":0,"company":"Curis","sponsor":"Sabine Mueller, MD, PhD","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Fimepinostat","moa":"Histone deacetylase | PI3-kinase p110-beta subunit | PI3-kinase p110-alpha subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase I","graph3":"Curis","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Curis \/ Sabine Mueller, MD, PhD","highestDevelopmentStatusID":"6","companyTruncated":"Curis \/ Sabine Mueller, MD, PhD"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : Fimepinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diffuse Intrinsic Pontine Glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 28, 2019

                          Lead Product(s) : Fimepinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Sabine Mueller, MD, PhD

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          HPCI India
                          Not Confirmed
                          HPCI India
                          Not Confirmed

                          Details : CUDC-907 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lymphoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 21, 2016

                          Lead Product(s) : Fimepinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Curis

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : CUDC-907 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Lymphoma, Large B-Cell, Diffuse.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 04, 2016

                          Lead Product(s) : Fimepinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : CUDC-907 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Triple Negative Breast Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 04, 2014

                          Lead Product(s) : Fimepinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : Fimepinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lymphoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 06, 2012

                          Lead Product(s) : Fimepinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Leukemia and Lymphoma Society

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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