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    [{"orgOrder":0,"company":"Acorda Therapeutics","sponsor":"Biogen","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Termination","leadProduct":"Fampridine","moa":"Voltage-gated potassium channel","graph1":"Neurology","graph2":"Approved FDF","graph3":"Acorda Therapeutics","amount2":0.51000000000000001,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0.51000000000000001,"dosageForm":"Tablet, Prolonged Release","sponsorNew":"Acorda Therapeutics \/ Biogen","highestDevelopmentStatusID":"15","companyTruncated":"Acorda Therapeutics \/ Biogen"},{"orgOrder":0,"company":"D'Youville College","sponsor":"Acorda Therapeutics | University at Buffalo","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Fampridine","moa":"Voltage-gated potassium channel","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"D'Youville College","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Pill","sponsorNew":"D'Youville College \/ Acorda Therapeutics | University at Buffalo","highestDevelopmentStatusID":"9","companyTruncated":"D'Youville College \/ Acorda Therapeutics | University at Buffalo"},{"orgOrder":0,"company":"Solaxa","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Fampridine","moa":"Voltage-gated potassium channel","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Solaxa","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Tablet, Disintegrating","sponsorNew":"Solaxa \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Solaxa \/ Inapplicable"}]

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    Fampridine

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                            01

                            Solaxa

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Solaxa Announces Phase 3 Clinical Trial for Spinocerebellar Ataxia Type 27B

                            Details : Solaxa is developing SLX-100 (dalfampridine), a small molecule drug, as a treatment for patients with spinocerebellar ataxia (SCA).

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 28, 2025

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Acorda Therapeutics

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Biogen

                            Deal Size : $510.0 million

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Acorda Therapeutics to Regain Global Commercialization Rights to FAMPYRA® by January 2025

                            Details : Following termination, Acorda regains global commercialization rights to Fampyra, a prolonged-release formulation of fampridine (4-aminopyridine) for adults with multiple sclerosis.

                            Product Name : Fampyra

                            Product Type : Other Small Molecule

                            Upfront Cash : $110.0 million

                            November 01, 2024

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Biogen

                            Deal Size : $510.0 million

                            Deal Type : Termination

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                            03

                            D'Youville College

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Acorda Therapeutics | University at Buffalo

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Effects of Physical Therapy and Dalfampridine on Functional Mobility in Non Ambulatory Persons With Multiple S...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 16, 2023

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Acorda Therapeutics | University at Buffalo

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Acorda Therapeutics

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 22, 2015

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Acorda Therapeutics

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate the Efficacy and Safety of Two Dose Strengths of Dalfampridine Extended Release Tablets.

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 22, 2014

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Biogen

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                            Biogen

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy and Safety Study of Prolonged-Release Fampridine in Participants With Multiple Sclerosis

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 19, 2014

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Johns Hopkins University

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Acorda Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety and Efficacy of Sustained Release Dalfampridine in Transverse Myelitis (Re-Launch)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 18, 2014

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Acorda Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Clinique Neuro-Outaouais

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                            Clinique Neuro-Outaouais

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Study Phase : Phase IV

                            Sponsor : CogState

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prolonged-release Fampridine as Adjunct Therapy to Active Motor Training in MS Patients

                            Details : Undisclosed

                            Product Name : Fampyra

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 26, 2014

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase IV

                            Sponsor : CogState

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            University of Southern Denmark

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                            University of Southern Denmark

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Study Phase : Phase IV

                            Sponsor : Region of Southern Denmark | Biogen

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Resistance Training and Amino Pyridine in Multiple Sclerosis

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 20, 2014

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase IV

                            Sponsor : Region of Southern Denmark | Biogen

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Neuro-Ophthalmologic Associates

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                            Neuro-Ophthalmologic Associates

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                            Lead Product(s) : Fampridine

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Acorda Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A New Medicine to Treat Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 03, 2013

                            Lead Product(s) : Fampridine

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Acorda Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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