Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Fampridine
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Solaxa Announces Phase 3 Clinical Trial for Spinocerebellar Ataxia Type 27B
Details : Solaxa is developing SLX-100 (dalfampridine), a small molecule drug, as a treatment for patients with spinocerebellar ataxia (SCA).
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 28, 2025
Lead Product(s) : Fampridine
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Biogen
Deal Size : $510.0 million
Deal Type : Termination
Acorda Therapeutics to Regain Global Commercialization Rights to FAMPYRA® by January 2025
Details : Following termination, Acorda regains global commercialization rights to Fampyra, a prolonged-release formulation of fampridine (4-aminopyridine) for adults with multiple sclerosis.
Product Name : Fampyra
Product Type : Other Small Molecule
Upfront Cash : $110.0 million
November 01, 2024
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Biogen
Deal Size : $510.0 million
Deal Type : Termination
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Acorda Therapeutics | University at Buffalo
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 16, 2023
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Acorda Therapeutics | University at Buffalo
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 22, 2015
Lead Product(s) : Fampridine
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 22, 2014
Lead Product(s) : Fampridine
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Efficacy and Safety Study of Prolonged-Release Fampridine in Participants With Multiple Sclerosis
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 19, 2014
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Acorda Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Safety and Efficacy of Sustained Release Dalfampridine in Transverse Myelitis (Re-Launch)
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 18, 2014
Lead Product(s) : Fampridine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Acorda Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Study Phase : Phase IV
Sponsor : CogState
Deal Size : Inapplicable
Deal Type : Inapplicable
Prolonged-release Fampridine as Adjunct Therapy to Active Motor Training in MS Patients
Details : Undisclosed
Product Name : Fampyra
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 26, 2014
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Highest Development Status : Phase IV
Sponsor : CogState
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Study Phase : Phase IV
Sponsor : Region of Southern Denmark | Biogen
Deal Size : Inapplicable
Deal Type : Inapplicable
Resistance Training and Amino Pyridine in Multiple Sclerosis
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 20, 2014
Lead Product(s) : Fampridine
Therapeutic Area : Neurology
Highest Development Status : Phase IV
Sponsor : Region of Southern Denmark | Biogen
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fampridine
Therapeutic Area : Ophthalmology
Study Phase : Phase IV
Sponsor : Acorda Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
A New Medicine to Treat Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 03, 2013
Lead Product(s) : Fampridine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase IV
Sponsor : Acorda Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable