[{"orgOrder":0,"company":"Acorda Therapeutics","sponsor":"Biogen","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Termination","leadProduct":"Fampridine","moa":"Voltage-gated potassium channel","graph1":"Neurology","graph2":"Approved FDF","graph3":"Acorda Therapeutics","amount2":0.51000000000000001,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0.51000000000000001,"dosageForm":"Oral Tablet, Prolonged Release","sponsorNew":"Acorda Therapeutics \/ Biogen","highestDevelopmentStatusID":"15","companyTruncated":"Acorda Therapeutics \/ Biogen"},{"orgOrder":0,"company":"D'Youville College","sponsor":"Acorda Therapeutics | University at Buffalo","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Fampridine","moa":"Voltage-gated potassium channel","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"D'Youville College","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Pill","sponsorNew":"D'Youville College \/ Acorda Therapeutics | University at Buffalo","highestDevelopmentStatusID":"9","companyTruncated":"D'Youville College \/ Acorda Therapeutics | University at Buffalo"},{"orgOrder":0,"company":"Solaxa","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Fampridine","moa":"Voltage-gated potassium channel","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Solaxa","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet, Disintegrating","sponsorNew":"Solaxa \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Solaxa \/ Inapplicable"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Coatings Trends
                          Not Confirmed
                          Coatings Trends
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                          Details : Solaxa is developing SLX-100 (dalfampridine), a small molecule drug, as a treatment for patients with spinocerebellar ataxia (SCA).

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 28, 2025

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Coatings Trends
                          Not Confirmed
                          Coatings Trends
                          Not Confirmed

                          Details : Following termination, Acorda regains global commercialization rights to Fampyra, a prolonged-release formulation of fampridine (4-aminopyridine) for adults with multiple sclerosis.

                          Product Name : Fampyra

                          Product Type : Other Small Molecule

                          Upfront Cash : $110.0 million

                          November 01, 2024

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Biogen

                          Deal Size : $510.0 million

                          Deal Type : Termination

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                          03

                          D'Youville College

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                          Coatings Trends
                          Not Confirmed

                          D'Youville College

                          Country arrow
                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 16, 2023

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Acorda Therapeutics | University at Buffalo

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Coatings Trends
                          Not Confirmed
                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 22, 2015

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Coatings Trends
                          Not Confirmed
                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 22, 2014

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Coatings Trends
                          Not Confirmed
                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 19, 2014

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Johns Hopkins University

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                          Coatings Trends
                          Not Confirmed

                          Johns Hopkins University

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                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 18, 2014

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Acorda Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Clinique Neuro-Outaouais

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                          Coatings Trends
                          Not Confirmed

                          Clinique Neuro-Outaouais

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                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Fampyra

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 26, 2014

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase IV

                          Sponsor : CogState

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          University of Southern Denmark

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                          Coatings Trends
                          Not Confirmed

                          University of Southern Denmark

                          Country arrow
                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 20, 2014

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase IV

                          Sponsor : Region of Southern Denmark | Biogen

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Neuro-Ophthalmologic Associates

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                          Coatings Trends
                          Not Confirmed

                          Neuro-Ophthalmologic Associates

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                          Coatings Trends
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 03, 2013

                          Lead Product(s) : Fampridine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Acorda Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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