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    [{"orgOrder":0,"company":"Milestone Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Etripamil","moa":"Calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Milestone Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Milestone Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Milestone Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Milestone Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Etripamil","moa":"Calcium 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III","graph3":"Milestone Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Milestone Pharmaceuticals \/ Piper Sandler","highestDevelopmentStatusID":"10","companyTruncated":"Milestone Pharmaceuticals \/ Piper Sandler"},{"orgOrder":0,"company":"Milestone Pharmaceuticals","sponsor":"Piper Sandler","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Etripamil","moa":"Calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Milestone Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Milestone Pharmaceuticals \/ Piper 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Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2021","type":"Collaboration","leadProduct":"Etripamil","moa":"Calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Milestone Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Milestone Pharmaceuticals \/ Xing Pharmaceuticals","highestDevelopmentStatusID":"10","companyTruncated":"Milestone Pharmaceuticals \/ Xing Pharmaceuticals"}]

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                            01

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Issues Complete Response Letter for Etripamil for PSVT

                            Details : Cardamyst (etripamil), a novel calcium channel blocker nasal spray, is being investigated for the management of paroxysmal supraventricular tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 28, 2025

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Milestone Pharmaceuticals Announces FDA Acceptance of New Drug Application for CARDAMYST„

                            Details : Cardamyst (etripamil), a novel calcium channel blocker nasal spray, is being investigated for the management of paroxysmal supraventricular tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 29, 2024

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Milestone Resubmits NDA for Etripamil for Paroxysmal Supraventricular Tachycardia

                            Details : MSP-2017 (etripamil) is a fast-acting, intranasally administered calcium-channel blocker, which is being evaluated for the treatment of Paroxysmal Supraventricular Tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 28, 2024

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Piper Sandler

                            Deal Size : $30.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Milestone Pharmaceuticals Prices $30 Million Public Offering of Common Shares and Warrants

                            Details : Milestone intends to use the net proceeds from the Offering to continue the development of Cardamyst (etripamil) in its lead indication of paroxysmal supraventricular tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 29, 2024

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Piper Sandler

                            Deal Size : $30.0 million

                            Deal Type : Public Offering

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                            05

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Piper Sandler

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Milestone Proposes Public Offering of Common Shares and Pre-Funded Warrants

                            Details : Milestone intends to use the net proceeds from the offering to continue the development of MSP-2017 (etripamil) in its lead indication of paroxysmal supraventricular tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 28, 2024

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Piper Sandler

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

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                            06

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Milestone Pharmaceuticals Announces Plan to Resubmit NDA for Etripamil to Treat PSVT

                            Details : MSP-2017 (etripamil) is a fast-acting, intranasally administered calcium-channel blocker, which is being evaluated for the treatment of Paroxysmal Supraventricular Tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 26, 2024

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Milestone Pharmaceuticals Receives Refusal to File Letter from U.S. FDA for New Drug Application for Etripamil...

                            Details : MSP-2017 (etripamil) is a novel calcium channel blocker. It is under phase 3 clinical development for the treatment of paroxysmal supraventricular tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 26, 2023

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Milestone Pharmaceuticals Announces Submission of New Drug Application to the U.S. FDA for Etripamil

                            Details : MSP-2017 (etripamil) is Milestone's lead investigational product. It is a novel calcium channel blocker nasal spray being developed for elevated and often highly symptomatic heart-rate attacks associated with PSVT and atrial fibrillation with a rapid ven...

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 24, 2023

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Milestone Pharmaceuticals Progresses Clinical and Regulatory Activities for Etripamil in Patients with Paroxys...

                            Details : MSP-2017 (etripamil) is a calcium channel antagonist potentially for the treatment of paroxysmal supraventricular tachycardia. It is designed to be a rapid-response therapy for elevated and often highly symptomatic heart rate attacks associated with PSVT...

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 03, 2023

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Milestone Pharmaceuticals

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                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : RTW Investments

                            Deal Size : $125.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Milestone Pharmaceuticals Announces $125 Million Strategic Financing with RTW Investments to Support the Advan...

                            Details : The net proceeds from the financing will be used to support the advancement of MSP-2017 (etripamil), a novel calcium channel blocker nasal spray, for paroxysmal supraventricular tachycardia.

                            Product Name : Cardamyst

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 28, 2023

                            Lead Product(s) : Etripamil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : RTW Investments

                            Deal Size : $125.0 million

                            Deal Type : Financing

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