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    [{"orgOrder":0,"company":"Epirium","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Plant Extract\/Herbal","year":"2020","type":"Inapplicable","leadProduct":"Epicatechin","moa":"Mitochondrial protein unspecific (MP)","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Epirium","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Epirium \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Epirium \/ Inapplicable"},{"orgOrder":0,"company":"Epirium","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Plant Extract\/Herbal","year":"2020","type":"Inapplicable","leadProduct":"Epicatechin","moa":"Mitochondrial protein unspecific (MP)","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Epirium","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Epirium \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Epirium \/ Inapplicable"},{"orgOrder":0,"company":"Piramal Pharma Solutions","sponsor":"Epirium","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Plant Extract\/Herbal","year":"2020","type":"Collaboration","leadProduct":"Epicatechin","moa":"Mitochondrial protein unspecific (MP)","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Piramal Pharma Solutions","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Piramal Pharma Solutions \/ Epirium","highestDevelopmentStatusID":"6","companyTruncated":"Piramal Pharma Solutions \/ Epirium"},{"orgOrder":0,"company":"Epirium","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Plant Extract\/Herbal","year":"2020","type":"Inapplicable","leadProduct":"Epicatechin","moa":"Mitochondrial protein unspecific (MP)","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Epirium","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Epirium \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Epirium \/ Inapplicable"}]

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                            01

                            Epirium

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                            Epirium

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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Epirium Bio Announces Commencement of Phase 1 Clinical Trial of EPM-01 in Becker Muscular Dystrophy

                            Details : The Phase 1 open-label, dose-escalation study is evaluating the safety, preliminary clinical efficacy and potential biomarkers of three doses of EPM-01 in participants with Becker or Becker-like muscular dystrophy.

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            December 08, 2020

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Piramal Pharma Solutions

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                            SCI Medicinal Chemistry
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                            Piramal Pharma Solutions

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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Epirium

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Piramal Pharma Solutions to Collaborate with Epirium Bio on Exclusive Integrated Development & Manufacturing P...

                            Details : Epirium has advanced its first clinical candidate EPM-01 (Epicatechin) in Becker muscular dystrophy and plans to follow with drug development targeting other disorders associated with mitochondrial dysfunction and tissue degeneration.

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Undisclosed

                            August 27, 2020

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Epirium

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            03

                            Epirium

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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            May 13, 2020

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Epirium

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                            SCI Medicinal Chemistry
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                            Epirium

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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Epirium Bio Receives FDA Orphan-Drug Designation for EB 002 for the Treatment of Duchenne and Becker Muscular ...

                            Details : The company's prior studies have shown that EB 002 can stimulate mitochondrial biogenesis, contributing to the restoration of tissue bioenergetics, thus upregulating key protein production.

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            April 14, 2020

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Craig McDonald

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                            SCI Medicinal Chemistry
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                            Craig McDonald

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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            (-)- Epicatechin Becker Muscular Dystrophy

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            August 02, 2017

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Craig McDonald

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                            SCI Medicinal Chemistry
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                            Craig McDonald

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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Plus Epicatechin Duchenne Muscular Dystrophy in Non-ambulatory Adolescents

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            November 16, 2016

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Ralitza Gavrilova

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                            SCI Medicinal Chemistry
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                            Ralitza Gavrilova

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                            SCI Medicinal Chemistry
                            Not Confirmed
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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            (+) Epicatechin to Treat Friedreich's Ataxia

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            January 21, 2016

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Veterans Medical Research Foundation

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                            SCI Medicinal Chemistry
                            Not Confirmed

                            Veterans Medical Research Foundation

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                            SCI Medicinal Chemistry
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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : San Diego Veterans Healthcare System | National Center for Complementary and Integrative Health | University of California, San Diego | National Institutes of Health

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            January 14, 2016

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : San Diego Veterans Healthcare System | National Center for Complementary and Integrative Health | University of California, San Diego | National Institutes of Health

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Veterans Medical Research Foundation

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                            SCI Medicinal Chemistry
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                            Veterans Medical Research Foundation

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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : National Institutes of Health | National Center for Complementary and Integrative Health | San Diego Veterans Healthcare System | University of California, San Diego

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            January 01, 2015

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : National Institutes of Health | National Center for Complementary and Integrative Health | San Diego Veterans Healthcare System | University of California, San Diego

                            Deal Size : Inapplicable

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                            10

                            Craig McDonald

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                            SCI Medicinal Chemistry
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                            Craig McDonald

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                            SCI Medicinal Chemistry
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                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Plant Extract/Herbal

                            Upfront Cash : Inapplicable

                            May 17, 2013

                            Lead Product(s) : Epicatechin

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Cardero Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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