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    [{"orgOrder":0,"company":"IMV","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CANADA","productType":"Vaccine","year":"2020","type":"Inapplicable","leadProduct":"Maveropepimut-S","moa":"||CD8 T-cell","graph1":"Oncology","graph2":"Phase II","graph3":"IMV","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"IMV \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"IMV \/ Undisclosed"},{"orgOrder":0,"company":"IMV","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CANADA","productType":"Vaccine","year":"2020","type":"Inapplicable","leadProduct":"Maveropepimut-S","moa":"||CD8 T-cell","graph1":"Oncology","graph2":"Phase II","graph3":"IMV","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"IMV \/ 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Lee","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Epacadostat","moa":"Indoleamine 2,3-dioxygenase","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Incyte Corporation \/ James J. Lee","highestDevelopmentStatusID":"7","companyTruncated":"Incyte Corporation \/ James J. Lee"},{"orgOrder":0,"company":"Merck & Co","sponsor":"George Albert Fisher","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Epacadostat","moa":"Indoleamine 2,3-dioxygenase","graph1":"Oncology","graph2":"Phase II","graph3":"Merck & Co","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Merck & Co \/ George Albert Fisher","highestDevelopmentStatusID":"8","companyTruncated":"Merck & Co \/ George Albert Fisher"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Chase Heaton","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Epacadostat","moa":"Indoleamine 2,3-dioxygenase","graph1":"Oncology","graph2":"Phase II","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Incyte Corporation \/ Chase Heaton","highestDevelopmentStatusID":"8","companyTruncated":"Incyte Corporation \/ Chase Heaton"}]

    Find Clinical Drug Pipeline Developments & Deals for Epacadostat

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                            01

                            IMV

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                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            IMV’s Survivin-Targeted T Cell Therapy Shows Durable Clinical Benefits in Phase 2 Study in Hard-to-Treat Adv...

                            Details : Results from the ongoing study continue to demonstrate prolonged clinical benefits, alongside favorable tolerability, and translational data linking the observed clinical benefits with DPX-Survivac’s mechanism of action.

                            Product Name : DPX-Survivac

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 03, 2020

                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            IMV

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                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            IMV to Present Data Highlights from the Phase 2 Trial of a Novel T-Cell Therapy

                            Details : The KOLs will provide an update on the ongoing Phase 2 trial with IMV’s novel T cell therapy in patients with advanced ovarian cancer, along with insights about the patients' experience.

                            Product Name : DPX-Survivac

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            November 13, 2020

                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Clinical Response and Translational Data from DeCidE1, Phase 2 Study of DPX-Survivac Immunotherapy in Advanced...

                            Details : Survivin-targeted T cell therapy continues to show significant, durable anti-tumor activity and is well-tolerated in this hard-to-treat cancer patient population.

                            Product Name : DPX-Survivac

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            May 29, 2020

                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            BriaCell Therapeutics

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                            BriaCell Therapeutics

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                            Lead Product(s) : SV-BR-1-GM,Epacadostat,INCMGA00012

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BriaCell Continues Business and Clinical Operations During COVID-19 Pandemic

                            Details : BriaCell's Phase I/IIa clinical study of Bria-IMT™, for breast cancer treatment, with Incyte’s immune checkpoint inhibitor, INCMGA00012, is ongoing and recruiting patients amidst COVID-19 pandemic.

                            Product Name : Bria-IMT

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            May 12, 2020

                            Lead Product(s) : SV-BR-1-GM,Epacadostat,INCMGA00012

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            BriaCell Therapeutics

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                            BriaCell Therapeutics

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                            Lead Product(s) : SV-BR-1-GM,Epacadostat,INCMGA00012

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BriaCell to Present Clinical Data at 2020 American Society of Clinical Oncology (ASCO) Annual Meeting May 29

                            Details : The presentation will highlight clinical data and pathological findings from the Phase I/IIa studies of Bria-IMT™ alone or in combination with checkpoint inhibitors in advanced breast cancer patients.

                            Product Name : Bria-IMT

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            March 31, 2020

                            Lead Product(s) : SV-BR-1-GM,Epacadostat,INCMGA00012

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            IMV

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                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            IMV Announces Breakthrough Data from DeCidE1

                            Details : First in-vivo T cell therapy to demonstrate clinical activity in hard-to-treat solid tumor.

                            Product Name : DPX-Survivac

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 25, 2020

                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            IMV

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                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            IMV to Report Updated Results from DeCidE1, its Ongoing Phase 2 Study of DPX-Survivac for Advanced Recurrent O...

                            Details : The Phase 2 study is evaluating IMV's lead compound, DPX-Survivac, in patients with advanced recurrent ovarian cancer.

                            Product Name : DPX-Survivac

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 20, 2020

                            Lead Product(s) : Maveropepimut-S,Cyclophosphamide,Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Incyte Corporation

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                            Incyte Corporation

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                            Lead Product(s) : Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Chase Heaton

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and Epacadostat

                            Details : Epacadostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Squamous Cell Carcinoma of Head and Neck.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 30, 2019

                            Lead Product(s) : Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Chase Heaton

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Washington University School of Medicine

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                            Washington University School of Medicine

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                            Lead Product(s) : Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Incyte Corporation | National Cancer Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

                            Details : Epacadostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Rectal Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 04, 2018

                            Lead Product(s) : Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Incyte Corporation | National Cancer Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins

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                            Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins

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                            Lead Product(s) : Epacadostat

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Incyte Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Window of Opportunity Study to Investigate Mechanisms of Actions of Novel Therapeutic Agents in Patients Wit...

                            Details : Epacadostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 20, 2018

                            Lead Product(s) : Epacadostat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Incyte Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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