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    [{"orgOrder":0,"company":"Hua Medicine","sponsor":"Covance","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CHINA","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Dorzagliatin","moa":"Hexokinase type IV","graph1":"Endocrinology","graph2":"Phase IV","graph3":"Hua Medicine","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hua Medicine \/ Covance","highestDevelopmentStatusID":"11","companyTruncated":"Hua Medicine \/ Covance"},{"orgOrder":0,"company":"Hua Medicine","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CHINA","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Dorzagliatin","moa":"Hexokinase type IV","graph1":"Endocrinology","graph2":"Phase IV","graph3":"Hua Medicine","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hua Medicine \/ Tigermed","highestDevelopmentStatusID":"11","companyTruncated":"Hua Medicine \/ Tigermed"},{"orgOrder":0,"company":"Hua Medicine","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CHINA","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Dorzagliatin","moa":"Hexokinase type IV","graph1":"Endocrinology","graph2":"Phase IV","graph3":"Hua Medicine","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hua Medicine \/ Tigermed","highestDevelopmentStatusID":"11","companyTruncated":"Hua Medicine \/ Tigermed"},{"orgOrder":0,"company":"Hua Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CHINA","productType":"Miscellaneous","year":"2013","type":"Inapplicable","leadProduct":"Dorzagliatin","moa":"Hexokinase type IV","graph1":"Endocrinology","graph2":"Phase IV","graph3":"Hua Medicine","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hua Medicine \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Hua Medicine \/ Undisclosed"},{"orgOrder":0,"company":"Hua Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CHINA","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Dorzagliatin","moa":"Hexokinase type IV","graph1":"Endocrinology","graph2":"Phase IV","graph3":"Hua Medicine","amount2":0,"highestDevelopmentShortName":"Ph 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I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hua Medicine \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Hua Medicine \/ Undisclosed"},{"orgOrder":0,"company":"Hua Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CHINA","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Dorzagliatin","moa":"Hexokinase type IV","graph1":"Undisclosed","graph2":"Phase I","graph3":"Hua Medicine","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hua Medicine \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Hua Medicine \/ Undisclosed"}]

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    Dorzagliatin

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                            01

                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase IV

                            Sponsor : Shanghai Branch, KunTuo Medical Research and Development (Beijing) Co., Ltd.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Post-Marketing Safety Study of Dorzagliatin in Patients With Type 2 Diabetes

                            Details : Dorzagliatin is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Diabetes Mellitus, Type 2.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 16, 2024

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase IV

                            Sponsor : Shanghai Branch, KunTuo Medical Research and Development (Beijing) Co., Ltd.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Bayer AG

                            Deal Size : $635.8 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Bayer and Hua Medicine Announce Commercialization Agreement

                            Details : Hua Medicine shall be responsible for clinical development, registration, product supply and distribution of dorzagliatin, whilst Bayer as the promotion service provider shall be responsible for marketing, promotion and medical education activities in Ch...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $43.3 million

                            August 17, 2020

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Bayer AG

                            Deal Size : $635.8 million

                            Deal Type : Agreement

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                            03

                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin,Metformin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Hua Medicine Announces Positive 24-Week Topline Results of Phase III Metformin Combination Trial of Dorzagliat...

                            Details : All subjects are treated with metformin (Glucophage) at 1500mg/day as basic therapy throughout the entire 52-week treatment period. Study met the primary efficacy and safety endpoints in the double-blinded placebo-controlled and randomized 24-week trial.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 01, 2020

                            Lead Product(s) : Dorzagliatin,Metformin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Clinical Study to Access the Pharmacokinetics of HMS5552 in Hepatic Impaired Subjects and Healthy Volunteers

                            Details : HMS5552 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 2.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 11, 2020

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Hua Medicine

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                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin,Empagliflozin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Hua Medicine Announces Positive Results of the Combination Study of Dorzagliatin with Empagliflozin (a SGLT-2 ...

                            Details : The PK results showed no impact of dorzagliatin and empagliflozin on respective PK properties under co-administration, supporting the us of this combination in the clinical setting.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 26, 2020

                            Lead Product(s) : Dorzagliatin,Empagliflozin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Clinical Study to Access the Pharmacokinetics of HMS5552 in Renal Impaired Subjects and Healthy Volunteers

                            Details : HMS5552 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 2.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 27, 2020

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Hua Medicine

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                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            DDI Study to Investigate the Impact of Itraconazole on the Pharmacokinetics of Dorzagliatin

                            Details : Dorzagliatin is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 06, 2019

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Hua Medicine

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                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            DDI Study Between Dorzagliatin and Rifampicin

                            Details : Dorzagliatin is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 06, 2019

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Hua Medicine

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                            OTS 2025
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                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Tigermed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Long-term Efficacy and Safety of HMS5552 in T2DM Subjects

                            Details : HMS5552 is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Diabetes Mellitus, Type 2.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 01, 2017

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Tigermed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Hua Medicine

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                            Hua Medicine

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                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Human Mass Balance Study of HMS5552 in Healthy Subjects

                            Details : HMS5552 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 18, 2017

                            Lead Product(s) : Dorzagliatin

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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