[{"orgOrder":0,"company":"Generium","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"RUSSIA","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Dornase Alfa","moa":"DNA","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Generium","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Nebulizer","sponsorNew":"Generium \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Generium \/ Undisclosed"},{"orgOrder":0,"company":"Generium","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"RUSSIA","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Dornase Alfa","moa":"DNA","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Generium","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nebulizer","sponsorNew":"Generium \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Generium \/ Undisclosed"},{"orgOrder":0,"company":"Georgetown University","sponsor":"Genentech","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Enzyme","year":"2011","type":"Inapplicable","leadProduct":"Dornase Alfa","moa":"DNA","graph1":"Infections and Infectious Diseases","graph2":"Phase IV","graph3":"Georgetown University","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Nebulizer","sponsorNew":"Georgetown University \/ Genentech","highestDevelopmentStatusID":"11","companyTruncated":"Georgetown University \/ Genentech"},{"orgOrder":0,"company":"University of Illinois, Chicago","sponsor":"Genentech | National Eye Institute","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Enzyme","year":"2016","type":"Inapplicable","leadProduct":"Dornase Alfa","moa":"DNA","graph1":"Immunology","graph2":"Phase I\/ Phase II","graph3":"University of Illinois, Chicago","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Solution","sponsorNew":"University of Illinois, Chicago \/ Genentech | National Eye Institute","highestDevelopmentStatusID":"7","companyTruncated":"University of Illinois, Chicago \/ Genentech | National Eye Institute"},{"orgOrder":0,"company":"McGill University Health Centre Research Institute","sponsor":"Hamilton Health Sciences | F. Hoffmann-La Roche | Exactis Innovation","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Dornase Alfa","moa":"DNA","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"McGill University Health Centre Research Institute","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"McGill University Health Centre Research Institute \/ Hamilton Health Sciences | F. Hoffmann-La Roche | Exactis Innovation","highestDevelopmentStatusID":"6","companyTruncated":"McGill University Health Centre Research Institute \/ Hamilton Health Sciences | F. Hoffmann-La Roche | Exactis Innovation"},{"orgOrder":0,"company":"Hershey Medical Center","sponsor":"Genentech","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Enzyme","year":"2010","type":"Inapplicable","leadProduct":"Dornase Alfa","moa":"DNA","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Phase III","graph3":"Hershey Medical Center","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Nebulizer","sponsorNew":"Hershey Medical Center \/ Genentech","highestDevelopmentStatusID":"10","companyTruncated":"Hershey Medical Center \/ Genentech"},{"orgOrder":0,"company":"Genentech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Enzyme","year":"2012","type":"Inapplicable","leadProduct":"Dornase Alfa","moa":"DNA","graph1":"Genetic Disease","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nebulizer","sponsorNew":"Genentech \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Undisclosed"}]

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                          01

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Tigerase (Dornase Alfa) is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Cystic Fibrosis.

                          Product Name : Tigerase

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          July 13, 2020

                          Lead Product(s) : Dornase Alfa

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Dornase Alfa is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of COVID-19.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          July 07, 2020

                          Lead Product(s) : Dornase Alfa

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          McGill University Health Centre Research Institute

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          McGill University Health Centre Research Institute

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Dornase Alfa is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of COVID-19.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          June 01, 2020

                          Lead Product(s) : Dornase Alfa

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Hamilton Health Sciences | F. Hoffmann-La Roche | Exactis Innovation

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          University of Illinois, Chicago

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          University of Illinois, Chicago

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Dornase Alfa is a Enzyme drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Graft vs Host Disease.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          March 08, 2016

                          Lead Product(s) : Dornase Alfa

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Genentech | National Eye Institute

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          05

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Dornase Alfa is a Enzyme drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Cystic Fibrosis.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          October 23, 2012

                          Lead Product(s) : Dornase Alfa

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Georgetown University

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Georgetown University

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Dornase Alfa is a Enzyme drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Respiratory Tract Infections.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          May 19, 2011

                          Lead Product(s) : Dornase Alfa

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Genentech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Hershey Medical Center

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Hershey Medical Center

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Dornase Alfa is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Sinusitis.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          July 02, 2010

                          Lead Product(s) : Dornase Alfa

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Phase III

                          Sponsor : Genentech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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