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    [{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Allergan Aesthetics","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"CANADA","productType":"Other Small Molecule","year":"2022","type":"Licensing Agreement","leadProduct":"Difluorocyclohexyloxyphenol","moa":"hTyr","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Allergan Aesthetics","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Allergan Aesthetics"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"RODAN & FIELDS LLC","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"CANADA","productType":"Other Small Molecule","year":"2022","type":"Termination","leadProduct":"Difluorocyclohexyloxyphenol","moa":"hTyr","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ RODAN & FIELDS LLC","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ RODAN & FIELDS LLC"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Difluorocyclohexyloxyphenol","moa":"Tyrosinase activity","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Inapplicable"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Difluorocyclohexyloxyphenol","moa":"Tyrosinase activity","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Inapplicable"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Difluorocyclohexyloxyphenol","moa":"Tyrosinase activity","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Inapplicable"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Difluorocyclohexyloxyphenol","moa":"Tyrosinase activity","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Undisclosed"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Promura GmbH","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"CANADA","productType":"Other Small Molecule","year":"2025","type":"Private Placement","leadProduct":"Difluorocyclohexyloxyphenol","moa":"Human tyrosinase","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Promura GmbH","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Promura GmbH"}]

    Find Clinical Drug Pipeline Developments & Deals for Difluorocyclohexyloxyphenol

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    Difluorocyclohexyloxyphenol

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                            01

                            Sirona Biochem Corp

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                            Sirona Biochem Corp

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                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Study Phase : Undisclosed

                            Sponsor : Promura GmbH

                            Deal Size : $2.1 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Sirona Inks Strategic Investment And JV Deal with Promura GmbH

                            Details : The proceeds will be used to advance the ongoing research and development of TFC-1067 for the treatment of dyschromia.

                            Product Name : TFC-1067

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            April 22, 2025

                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Highest Development Status : Undisclosed

                            Sponsor : Promura GmbH

                            Deal Size : $2.1 million

                            Deal Type : Private Placement

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                            02

                            Sirona Biochem Corp

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                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Study Phase : Undisclosed

                            Sponsor : Allergan Aesthetics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Sirona Biochem Announces Exclusive Global Licensing Agreement with Allergan Aesthetics

                            Details : Under Licensing agreement with Sirona, pursuant to which Allergan Aesthetics will develop and commercialize topical skin care treatments based on active ingredients derived from certain of Sirona’s patents for TFC-1067 (Difluorocyclohexyloxyphenol) and...

                            Product Name : TFC-1067

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 13, 2022

                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Highest Development Status : Undisclosed

                            Sponsor : Allergan Aesthetics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            03

                            Sirona Biochem Corp

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                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Study Phase : Undisclosed

                            Sponsor : RODAN & FIELDS LLC

                            Deal Size : Undisclosed

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Sirona Biochem Announces the Termination of Supply Agreement with Rodan + Fields

                            Details : Under the terms of the agreement, Sirona will manufacture and supply TFC-1067 (difluorocyclohexyloxyphenol), a novel, new skin brightening ingredient, for use by Rodan + Fields on a non-exclusive basis and Rodan + Fields will launch a new product incorpo...

                            Product Name : TFC-1067

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 16, 2022

                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Highest Development Status : Undisclosed

                            Sponsor : RODAN & FIELDS LLC

                            Deal Size : Undisclosed

                            Deal Type : Termination

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                            04

                            Sirona Biochem Corp

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                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Study Phase : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sirona Biochem Announces Acceptance of Clinical Study for TFC-1067 in the Journal of Cosmetic Dermatology

                            Details : Study conducted by Dr. Zoe Draelos has been peer reviewed & accepted for publication in the Journal of Cosmetic Dermatology. TFC-1067 demonstrated the ability to lighten dark spots to blend into surrounding skin while preserving overall complexion.

                            Product Name : TFC-1067

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 26, 2020

                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Highest Development Status : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Sirona Biochem Corp

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                            Sirona Biochem Corp

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                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Study Phase : Undisclosed

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Sirona Biochem Signs Agreement with Global Pharmaceutical Company for Clinical Trial of its Novel Skincare Com...

                            Details : Multiple parameters will be measured including the added effects of the higher concentration of TFC-1067 and a boosted formulation. TFC-1067 has been clinically proven to selectively lighten dark spots and blend them into surrounding skin tone.

                            Product Name : TFC-1067

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 13, 2020

                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Highest Development Status : Undisclosed

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Sirona Biochem Corp

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                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Study Phase : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sirona Biochem Ships First Batch of TFC-1067 to Rodan + Fields

                            Details : Sirona has made its first shipment of compound, TFC-1067 to Rodan + Fields. Rodan + Fields will be the first to market for a consumer product utilizing TFC-1067 for the treatment of dyschromia.

                            Product Name : TFC-1067

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 16, 2020

                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Highest Development Status : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Sirona Biochem Corp

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                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Study Phase : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sirona Biochem: 100% Safety in Final Tox Study for Increased Concentration of TFC-1067

                            Details : TFC-1067 demonstrated very good skin compatibility and does not show a sensitizing effect.

                            Product Name : TFC-1067

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 22, 2020

                            Lead Product(s) : Difluorocyclohexyloxyphenol

                            Therapeutic Area : Dermatology

                            Highest Development Status : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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