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    [{"orgOrder":0,"company":"Revolution Medicines","sponsor":"J.P. Morgan","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Public Offering","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase I","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Revolution Medicines \/ J.P. Morgan","highestDevelopmentStatusID":"6","companyTruncated":"Revolution Medicines \/ J.P. Morgan"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase III","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Revolution Medicines \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Revolution Medicines \/ Inapplicable"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase III","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Revolution Medicines \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Revolution Medicines \/ Inapplicable"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase I","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Revolution Medicines \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Revolution Medicines \/ Inapplicable"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase I","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Revolution Medicines \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Revolution Medicines \/ Inapplicable"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"J.P. Morgan","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Public Offering","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase I","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Revolution Medicines \/ J.P. Morgan","highestDevelopmentStatusID":"6","companyTruncated":"Revolution Medicines \/ J.P. Morgan"},{"orgOrder":0,"company":"EQRx","sponsor":"Revolution Medicines","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Acquisition","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase I","graph3":"EQRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"EQRx \/ Revolution Medicines","highestDevelopmentStatusID":"6","companyTruncated":"EQRx \/ Revolution Medicines"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"J.P. 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Morgan","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase III","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Revolution Medicines \/ J.P. Morgan","highestDevelopmentStatusID":"10","companyTruncated":"Revolution Medicines \/ J.P. Morgan"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"J.P. 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Morgan"},{"orgOrder":0,"company":"EQRx","sponsor":"Revolution Medicines","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Acquisition","leadProduct":"Daraxonrasib","moa":"RAS","graph1":"Oncology","graph2":"Phase I","graph3":"EQRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"EQRx \/ Revolution Medicines","highestDevelopmentStatusID":"6","companyTruncated":"EQRx \/ Revolution Medicines"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Daraxonrasib","moa":"RAS(ON)","graph1":"Oncology","graph2":"Phase III","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Revolution Medicines \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Revolution Medicines \/ Inapplicable"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"Royalty Pharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Financing","leadProduct":"Daraxonrasib","moa":"RAS(ON)","graph1":"Oncology","graph2":"Phase III","graph3":"Revolution Medicines","amount2":1.25,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":1.25,"dosageForm":"Oral Tablet","sponsorNew":"Revolution Medicines \/ Royalty Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Revolution Medicines \/ Royalty Pharma"},{"orgOrder":0,"company":"Revolution Medicines","sponsor":"Summit Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Collaboration","leadProduct":"Daraxonrasib","moa":"||RAS(ON)","graph1":"Oncology","graph2":"Phase III","graph3":"Revolution Medicines","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Revolution Medicines \/ Summit Therapeutics","highestDevelopmentStatusID":"10","companyTruncated":"Revolution Medicines \/ Summit Therapeutics"}]

    Find Clinical Drug Pipeline Developments & Deals for Daraxonrasib

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                            01

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib,Ivonescimab

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Sponsor : Summit Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Revolution and Summit Collaborates to Evaluate RAS(ON) Inhibitors with Ivonescimab

                            Details : The collaboration aims to evaluate clinical-stage RAS(ON) inhibitors, including RMC-6236 (daraxonrasib), RMC-9805 (zoldonrasib) and RMC-6291 (elironrasib), in combination with ivonescimab.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 30, 2025

                            Lead Product(s) : Daraxonrasib,Ivonescimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Sponsor : Summit Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Royalty Pharma

                            Deal Size : $1,250.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Revolution Medicines Enters into $2 Billion Flexible Funding Agreement with Royalty Pharma

                            Details : The financing aims to advance the development and global commercialization of Revolution's leading RAS(ON) inhibitor portfolio, RMC-6236 (daraxonrasib), is being evaluated for RAS-mutated NSCLC.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 24, 2025

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Royalty Pharma

                            Deal Size : $1,250.0 million

                            Deal Type : Financing

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                            03

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Revolution Medicines Doses First Patient in Phase 3 Trial of Daraxonrasib

                            Details : RMC-6236 (daraxonrasib) is an oral, direct RAS(ON) multi-selective inhibitor with the potential to help address a wide range of cancers driven by oncogenic RAS mutations.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 14, 2025

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Revolution Medicines Doses First Patient in Phase 3 Metastatic Pancreatic Trial

                            Details : RMC-6236 is a small molecule, RAS(ON) multi-selective inhibitor, given orally. It is being investigated for previously treated pancreatic ductal adenocarcinoma.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 21, 2024

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Revolution Medicines to Update RMC-6236 Pancreatic Cancer Program on July 15, 2024

                            Details : RMC-6236 is a small molecule, RAS(ON) multi-selective inhibitor, given orally. It is being investigated for the treatment of pancreatic ductal adenocarcinoma.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 07, 2024

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $862.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Revolution Medicines Closes $750M Offering with Full Exercise of Additional Shares

                            Details : The net proceeds will be used to support the clinical development of the company’s late-stage product, RMC-6236, which is being studied as a treatment for RAS-mutated Pancreatic Ductal Adenocarcinoma.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 12, 2024

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $862.5 million

                            Deal Type : Public Offering

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                            07

                            Revolution Medicines

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                            Revolution Medicines

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                            Not Confirmed
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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $750.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Revolution Medicines Prices Upsized $750M Offering of Stock & Pre-Funded Warrants

                            Details : The net proceeds will be used to support the clinical development of the company’s late-stage product, RMC-6236, which is being studied as a treatment for RAS-mutated Pancreatic Ductal Adenocarcinoma.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 12, 2024

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $750.0 million

                            Deal Type : Public Offering

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                            08

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $600.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Revolution Medicines Announces Commencement of Public Offering of Common Stock

                            Details : The net proceeds will be used to support the clinical development of the company’s late-stage product, RMC-6236, which is being studied as a treatment for RAS-mutated Pancreatic Ductal Adenocarcinoma.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 12, 2024

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $600.0 million

                            Deal Type : Public Offering

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                            09

                            EQRx

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                            EQRx

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Revolution Medicines

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Revolution Medicines Completes Acquisition of EQRx

                            Details : Through the acquisition, Revolution expects to conduct late-stage development of RAS(ON) inhibitor drug candidate pipeline, including RMC-6236, in multiple RAS-driven cancers.

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 11, 2023

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Revolution Medicines

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            10

                            Revolution Medicines

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                            Revolution Medicines

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                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : J.P. Morgan

                            Deal Size : $345.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Revolution Medicines Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' O...

                            Details : The net proceeds will be used to fund development of RAS(ON) Inhibitor programs, including clinical development of RMC-6236 and RMC-6291 and advancement of RMC-9805 and RAS Companion Inhibitor programs, including RMC-4630 and RMC-5552 into clinical devel...

                            Product Name : RMC-6236

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            July 03, 2023

                            Lead Product(s) : Daraxonrasib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : J.P. Morgan

                            Deal Size : $345.0 million

                            Deal Type : Public Offering

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