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    [{"orgOrder":0,"company":"WEX Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CANADA","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Tetrodotoxin","moa":"fluoroquinolone derivatives","graph1":"Neurology","graph2":"Phase II","graph3":"WEX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"WEX Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"WEX Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"WEX Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CANADA","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Tetrodotoxin","moa":"fluoroquinolone derivatives","graph1":"Neurology","graph2":"Phase II","graph3":"WEX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"WEX Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"WEX Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"WEX Pharmaceuticals","sponsor":"Dogwood Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Merger","leadProduct":"Tetrodotoxin","moa":"fluoroquinolone derivatives","graph1":"Neurology","graph2":"Phase II","graph3":"WEX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"WEX Pharmaceuticals \/ WEX Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"WEX Pharmaceuticals \/ WEX Pharmaceuticals"},{"orgOrder":0,"company":"WEX Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CANADA","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Tetrodotoxin","moa":"fluoroquinolone derivatives","graph1":"Neurology","graph2":"Phase II","graph3":"WEX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection, Powder, Lyophilized","sponsorNew":"WEX Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"WEX Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"WEX Pharmaceuticals","sponsor":"Premier Research Group","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CANADA","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Tetrodotoxin","moa":"fluoroquinolone derivatives","graph1":"Neurology","graph2":"Phase II","graph3":"WEX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"WEX Pharmaceuticals \/ Premier Research Group","highestDevelopmentStatusID":"8","companyTruncated":"WEX Pharmaceuticals \/ Premier Research Group"},{"orgOrder":0,"company":"WEX Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CANADA","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Tetrodotoxin","moa":"fluoroquinolone derivatives","graph1":"Undisclosed","graph2":"Phase I","graph3":"WEX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"WEX Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"WEX Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"WEX Pharmaceuticals","sponsor":"Celerion","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CANADA","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Tetrodotoxin","moa":"fluoroquinolone derivatives","graph1":"Undisclosed","graph2":"Phase I","graph3":"WEX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"WEX Pharmaceuticals \/ Celerion","highestDevelopmentStatusID":"6","companyTruncated":"WEX Pharmaceuticals \/ Celerion"},{"orgOrder":0,"company":"Polynoma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2012","type":"Inapplicable","leadProduct":"POL-103A","moa":"Immunostimulant","graph1":"Oncology","graph2":"Phase III","graph3":"Polynoma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Polynoma \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Polynoma \/ Undisclosed"},{"orgOrder":0,"company":"Polynoma","sponsor":"US Food & Drug Administration","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"Seviprotimut-L","moa":"Immunostimulant","graph1":"Oncology","graph2":"Phase III","graph3":"Polynoma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Polynoma \/ US Food & Drug Administration","highestDevelopmentStatusID":"10","companyTruncated":"Polynoma \/ US Food & Drug Administration"},{"orgOrder":0,"company":"Polynoma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Inapplicable","leadProduct":"Seviprotimut-L","moa":"Immunostimulant","graph1":"Oncology","graph2":"Phase III","graph3":"Polynoma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Polynoma \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Polynoma \/ Undisclosed"},{"orgOrder":0,"company":"Polynoma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Inapplicable","leadProduct":"Seviprotimut-L","moa":"Immunostimulant","graph1":"Oncology","graph2":"Phase III","graph3":"Polynoma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Polynoma \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Polynoma \/ Undisclosed"},{"orgOrder":0,"company":"CK Life Sciences","sponsor":"XtalPi","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Discovery Platform","graph3":"CK Life Sciences","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CK Life Sciences \/ CK Life Sciences","highestDevelopmentStatusID":"3","companyTruncated":"CK Life Sciences \/ CK Life Sciences"},{"orgOrder":0,"company":"Polynoma","sponsor":"TransCode Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2025","type":"Acquisition","leadProduct":"Seviprotimut-L","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase III","graph3":"Polynoma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Polynoma \/ TransCode Therapeutics","highestDevelopmentStatusID":"10","companyTruncated":"Polynoma \/ TransCode Therapeutics"}]

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                            01

                            Polynoma

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                            Polynoma

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                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : TransCode Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            TransCode Rewrites Future, Securing $25M and Phase 3 Vaccine

                            Details : TransCode expands its microRNA-based pipeline with Polynoma's Phase 3-ready seviprotimut-L, a novel polyvalent shed antigen vaccine for the adjuvant treatment of melanoma.

                            Product Name : POL-103A

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            October 08, 2025

                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : TransCode Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

                            WEX Pharmaceuticals

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                            AIChE Annual Meeting
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                            WEX Pharmaceuticals

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                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Recipient : Dogwood Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Virios Therapeutics And Wex Pharmaceuticals Form Dogwood Therapeutics

                            Details : The combined company will be focused on Halneuron, in Phase 2b for chemotherapy-induced neuropathic pain, IMC-1, poised for Phase 3 for fibromyalgia and IMC-2 to treat Long-COVID sequelae.

                            Product Name : Halneuron

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            October 07, 2024

                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Recipient : Dogwood Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            03

                            WEX Pharmaceuticals

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                            AIChE Annual Meeting
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                            WEX Pharmaceuticals

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                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Wex Pharmaceuticals Inc. Commences Its Quantitative Sensory Testing Clinical Trial Evaluating the Impact of Ha...

                            Details : Halneuron (tetrodotoxin injectable formulation), a selective sodium channel blocker, produces analgesia either by decreasing the propagation of action potentials by sodium channels, being developed for Neuropathic Pain.

                            Product Name : Halneuron

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 11, 2023

                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            WEX Pharmaceuticals

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                            WEX Pharmaceuticals

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                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Wex Pharmaceuticals Inc. Enrolls the First Patient in the Phase 2b Clinical Trial Evaluating the Efficacy and ...

                            Details : Halneuron (Tetrodotoxin injectable formulation), a selective sodium channel blocker, produces analgesia either by decreasing the propagation of action potentials by sodium channels and/or by blocking ectopic discharges associated with chronic pain.

                            Product Name : Halneuron

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 03, 2023

                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            CK Life Sciences

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                            AIChE Annual Meeting
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                            CK Life Sciences

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Recipient : XtalPi

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            XtalPi and CK Life Sciences to Collaborate in AI-empowered Tumour Vaccine Research And Development, Opening A ...

                            Details : XtalPi and CK Life Sciences will leverage their respective expertise to jointly develop a novel AI tumour vaccine R&D platform to improve the discovery and design capabilities of tumour vaccines and accelerate the development of more vaccine types.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            November 24, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Recipient : XtalPi

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

                            WEX Pharmaceuticals

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                            WEX Pharmaceuticals

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                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodo...

                            Details : Tetrodotoxin is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Chemotherapy-induced Neuralgia.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 03, 2022

                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Polynoma

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                            Polynoma

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                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : US Food & Drug Administration

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Polynoma Receives Special Protocol Assessment (SPA) Agreement from the U.S. FDA for a Pivotal Phase 3 Clinical...

                            Details : Seviprotimut-L stimulates humoral and cellular immune response, is in clinical development as a potential adjuvant treatment for patients 60 years and younger with Stage IIB or IIC melanoma.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            January 11, 2022

                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : US Food & Drug Administration

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Polynoma

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                            Polynoma

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                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Polynoma Receives FDA Fast Track Designation for its Melanoma Cancer Vaccine Seviprotimut-L

                            Details : U.S. Food and Drug Administration (FDA) has granted Polynoma's application for Fast Track designation of seviprotimut-L, its melanoma cancer vaccine for the adjuvant treatment of stage IIB/IIC melanoma patients post-resection to improve recurrence-free s...

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            June 23, 2020

                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Polynoma

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                            Polynoma

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                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Polynoma Presenting Final Analysis of MAVIS Phase III Part B1 Data of Its Investigational Melanoma Vaccine, Se...

                            Details : Study data show a durable recurrence-free survival clinical benefit in patients with localized melanoma, supporting the potential use of seviprotimut-L as an adjuvant treatment.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            May 13, 2020

                            Lead Product(s) : Seviprotimut-L

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            WEX Pharmaceuticals

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                            WEX Pharmaceuticals

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                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Celerion

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 1, Single Ascending Dose, Randomized, Double-Blind, Placebo and Positive Controlled Study to Evaluate ...

                            Details : Tetrodotoxin is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 10, 2019

                            Lead Product(s) : Tetrodotoxin

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Celerion

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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