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III","graph3":"BioCardia","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"BioCardia \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"BioCardia \/ Undisclosed"},{"orgOrder":0,"company":"Cytokinetics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Private Placement","leadProduct":"Aficamten","moa":"MYH6_7","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Cytokinetics","amount2":0.55000000000000004,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0.55000000000000004,"dosageForm":"Tablet","sponsorNew":"Cytokinetics \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cytokinetics \/ Undisclosed"},{"orgOrder":0,"company":"BioCardia","sponsor":"H.C. Wainwright & Co","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2025","type":"Public Offering","leadProduct":"BCDA-01","moa":"Undisclosed","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"BioCardia","amount2":0.01,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0.01,"dosageForm":"Infusion","sponsorNew":"BioCardia \/ H.C. Wainwright & Co","highestDevelopmentStatusID":"10","companyTruncated":"BioCardia \/ H.C. Wainwright & Co"},{"orgOrder":0,"company":"Alnylam Pharmaceuticals","sponsor":"F. Hoffmann-La Roche","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Oligonucleotide","year":"2025","type":"Inapplicable","leadProduct":"Zilebesiran","moa":"Angiotensinogen messenger RNA (AGT mRNA)","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Alnylam Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Alnylam Pharmaceuticals \/ F. Hoffmann-La Roche","highestDevelopmentStatusID":"10","companyTruncated":"Alnylam Pharmaceuticals \/ F. Hoffmann-La Roche"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            BioCardia

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                            Aus. Peptide Conference
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                            BioCardia

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                            Lead Product(s) : BCDA-01

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : H.C. Wainwright & Co

                            Deal Size : $12.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            BioCardia Announces Pricing of Up To $12 Million Public Offering

                            Details : The proceeds will be used for advancing company's investigational biotherapeutic candidates, including BCDA-01, CardiAMP autologous mononuclear cell therapy for ischemic heart failure.

                            Product Name : BCDA-01

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            September 18, 2025

                            Lead Product(s) : BCDA-01

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : H.C. Wainwright & Co

                            Deal Size : $12.0 million

                            Deal Type : Public Offering

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                            02

                            Alnylam Pharmaceuticals

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                            Aus. Peptide Conference
                            Not Confirmed

                            Alnylam Pharmaceuticals

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Zilebesiran

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular...

                            Details : Zilebesiran is a Oligonucleotide drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Cardiovascular Diseases.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            September 18, 2025

                            Lead Product(s) : Zilebesiran

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Cytokinetics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed

                            Cytokinetics

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                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
                            • EDQM
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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Aficamten

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $550.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Cytokinetics Announces Proposed Private Placement of $550.0 Million

                            Details : Cytokinetics intends to use the net proceeds to support the potential commercial launch of aficamten, a cardiac myosin inhibitor, being developed for obstructive hypertrophic cardiomyopathy.

                            Product Name : CK-3773274

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 16, 2025

                            Lead Product(s) : Aficamten

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $550.0 million

                            Deal Type : Private Placement

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                            04

                            Mineralys Therapeutics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed

                            Mineralys Therapeutics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $287.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Mineralys Therapeutics Announces Closing of Upsized $287.5 Million

                            Details : Mineralys intends to use the net proceeds to fund clinical development of lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 04, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $287.5 million

                            Deal Type : Public Offering

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                            05

                            Mineralys Therapeutics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed

                            Mineralys Therapeutics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $250.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Mineralys Therapeutics Announces Pricing of Upsized $250.0 Million

                            Details : Mineralys intends to use the net proceeds to fund clinical development of lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 02, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $250.0 million

                            Deal Type : Public Offering

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                            06

                            Mineralys Therapeutics

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                            Aus. Peptide Conference
                            Not Confirmed

                            Mineralys Therapeutics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
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                            • WHO-GMP
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Mineralys Therapeutics Announces Proposed Public Offering of Common Stock

                            Details : Mineralys intends to use the net proceeds to fund clinical development of lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 02, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

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                            07

                            Amgen Inc

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                            Aus. Peptide Conference
                            Not Confirmed

                            Amgen Inc

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                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Maridebart Cafraglutide

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Maridebart Cafraglutide Effect on Cardiovascular Outcomes in Obese Participants with ASCVD

                            Details : Maridebart Cafraglutide is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Atherosclerosis.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            June 25, 2025

                            Lead Product(s) : Maridebart Cafraglutide

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Amgen Inc

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                            Aus. Peptide Conference
                            Not Confirmed

                            Amgen Inc

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Maridebart Cafraglutide

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Maridebart Cafraglutide in Heart Failure with Preserved or Reduced Ejection Fraction

                            Details : Maridebart Cafraglutide is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Heart Failure, Diastolic.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            June 25, 2025

                            Lead Product(s) : Maridebart Cafraglutide

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Cytokinetics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed

                            Cytokinetics

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Aficamten

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cytokinetics Announces Positive Topline Results From MAPLE-HCM

                            Details : CK-3773274 (aficamten) is an investigational selective, small molecule cardiac myosin inhibitor, being developed in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM).

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 13, 2025

                            Lead Product(s) : Aficamten

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            BioCardia

                            U.S.A arrow
                            Aus. Peptide Conference
                            Not Confirmed

                            BioCardia

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                            Aus. Peptide Conference
                            Not Confirmed
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                            Lead Product(s) : BCDA-02

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BioCardia Doses First Patient in CardiAMP HF II Phase 3 Heart Trial

                            Details : CardiAMP cell therapy is the first treatment utilizing patient's own cells for the treatment. It is being evaluated for treating ischemic etiology heart failure of reduced ejection fraction.

                            Product Name : CardiAMP

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            May 01, 2025

                            Lead Product(s) : BCDA-02

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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