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    [{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"University of Arizona","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2012","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"Ornithine decarboxylase","graph1":"Oncology","graph2":"Phase II","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cancer Prevention Pharmaceuticals \/ University of Arizona","highestDevelopmentStatusID":"8","companyTruncated":"Cancer Prevention Pharmaceuticals \/ University of Arizona"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Amino Acid","year":"2010","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"Ornithine decarboxylase","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Amino Acid","year":"2011","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"Ornithine decarboxylase","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Amino Acid","year":"2020","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"||Ornithine decarboxylase","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Amino Acid","year":"2020","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"||Ornithine decarboxylase","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Amino Acid","year":"2020","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"||Ornithine decarboxylase","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Panbela Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Amino Acid","year":"2022","type":"Acquisition","leadProduct":"Eflornithine Hydrochloride","moa":"||Ornithine decarboxylase","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0.059999999999999998,"dosageForm":"Tablet","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Panbela Therapeutics","highestDevelopmentStatusID":"10","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Panbela Therapeutics"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Panbela Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Amino Acid","year":"2022","type":"Acquisition","leadProduct":"Eflornithine Hydrochloride","moa":"||Ornithine decarboxylase","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Cancer Prevention Pharmaceuticals","amount2":0.059999999999999998,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0.059999999999999998,"dosageForm":"Tablet","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Panbela Therapeutics","highestDevelopmentStatusID":"10","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Panbela Therapeutics"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Giselle Sholler","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"ODC","graph1":"Oncology","graph2":"Phase I","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Giselle Sholler","highestDevelopmentStatusID":"6","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Giselle Sholler"},{"orgOrder":0,"company":"Cancer Prevention Pharmaceuticals","sponsor":"Emily K. Sims","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2022","type":"Inapplicable","leadProduct":"Eflornithine Hydrochloride","moa":"Ornithine decarboxylase","graph1":"Endocrinology","graph2":"Phase II","graph3":"Cancer Prevention Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cancer Prevention Pharmaceuticals \/ Emily K. Sims","highestDevelopmentStatusID":"8","companyTruncated":"Cancer Prevention Pharmaceuticals \/ Emily K. Sims"}]

    Find Clinical Drug Pipeline Developments & Deals by Cancer Prevention Pharmaceuticals

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                            01

                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase II

                            Sponsor : Emily K. Sims

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TArgeting Type 1 Diabetes Using POLyamines (TADPOL)

                            Details : Difluoromethylornithine is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Diabetes Mellitus, Type 1.

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            October 26, 2022

                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase II

                            Sponsor : Emily K. Sims

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Panbela Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Panbela Therapeutics, Inc. Closes Acquisition of Cancer Prevention Pharmaceuticals, Inc.

                            Details : Flynpovi is a combination of CPP-1X (eflornithine) and sulindac with a dual mechanism inhibiting polyamine synthesis and increase polyamine export and catabolism. The safety profile for Flynpovi did not differ from the single agents and supports the eval...

                            Product Name : Undisclosed

                            Product Type : Amino Acid

                            Upfront Cash : Undisclosed

                            June 16, 2022

                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Panbela Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            03

                            Cancer Prevention Pharmaceuticals

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Panbela Therapeutics

                            Deal Size : $60.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Panbela Therapeutics, Inc. to Acquire Cancer Prevention Pharmaceuticals, Inc.

                            Details : The combined entity will have an expanded pipeline addressing focus: familial adenomatous polyposis (FAP), first-line metastatic pancreatic cancer, neoadjuvant pancreatic cancer, colorectal cancer prevention and ovarian cancer, including Flynpovi, the le...

                            Product Name : Undisclosed

                            Product Type : Amino Acid

                            Upfront Cash : Undisclosed

                            February 22, 2022

                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Panbela Therapeutics

                            Deal Size : $60.0 million

                            Deal Type : Acquisition

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                            04

                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cancer Prevention Pharmaceuticals Publishes Landmark Phase 3 Clinical Trial Data for Treatment of Familial Ade...

                            Details : Although the trial did not demonstrate that overall disease progression was significantly lower with CPP-1X/sul compared to eflornithine or sulindac alone, in a subgroup of patients with intact colons there was a 70% decreased risk of disease progression...

                            Product Name : Undisclosed

                            Product Type : Amino Acid

                            Upfront Cash : Inapplicable

                            September 11, 2020

                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Cancer Prevention Pharmaceuticals

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cancer Prevention Pharmaceuticals Submits New Drug Application to the FDA for CPP-1X/sul for Treatment of Fami...

                            Details : The clinical development of CPP-1X/sul was designed to establish this fixed dose combination product as a potential pharmaco-preventive drug treatment specifically for FAP patients.

                            Product Name : Undisclosed

                            Product Type : Amino Acid

                            Upfront Cash : Inapplicable

                            June 29, 2020

                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cancer Prevention Pharmaceuticals Submits EU Marketing Authorization Application for CPP-1X/sul to Treat Famil...

                            Details : Cancer Prevention Pharmaceuticals plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration this month seeking accelerated approval for CPP-IX/sul for the same indication.

                            Product Name : Undisclosed

                            Product Type : Amino Acid

                            Upfront Cash : Inapplicable

                            June 18, 2020

                            Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Cancer Prevention Pharmaceuticals

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : University of Arizona

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Urinary Biomarker Study With Sulindac and Difluoromethylornithine

                            Details : Difluoromethylornithine is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            July 10, 2012

                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : University of Arizona

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Cancer Prevention Pharmaceuticals

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)

                            Details : Eflornithine is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Adenomatous Polyposis Coli.

                            Product Name : Undisclosed

                            Product Type : Amino Acid

                            Upfront Cash : Inapplicable

                            December 01, 2011

                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Cancer Prevention Pharmaceuticals

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)

                            Details : Eflornithine is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Adenomatous Polyposis Coli.

                            Product Name : Undisclosed

                            Product Type : Amino Acid

                            Upfront Cash : Inapplicable

                            November 23, 2010

                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Cancer Prevention Pharmaceuticals

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Cancer Prevention Pharmaceuticals

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                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Giselle Sholler

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety Study for Refractory or Relapsed Neuroblastoma With DFMO Alone and in Combination With Etoposide

                            Details : DFMO is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neuroblastoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 29, 2010

                            Lead Product(s) : Eflornithine Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Giselle Sholler

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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