

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Repare Therapeutics Announces Positive Results from Lunresertib, Camonsertib Combo Trial
Details : RP-6306 (lunresertib), a first-in-class, selective and potent oral small molecule inhibitor of PKMYT1, is being developed in combination with Camonsertib for the treatment of endometrial cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 12, 2024
Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : The Division of Cancer Treatment and Diagnosis
Deal Size : Undisclosed
Deal Type : Agreement
Repare Partners with US NCI To Advance Camonsertib Development
Details : The agreement aims to advance the development of camonsertib, a potential best-in-class oral small molecule ATR inhibitor, currently in Phase 1/2 in patients with ATM-altered tumors.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 12, 2024
Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : The Division of Cancer Treatment and Diagnosis
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Repare Shares Positive Phase 1 Data From MYTHIC Safety and Tolerability Study
Details : RP-6306 (lunresertib) in combination with RP-3500 (camonsertib) is being evaluated for the treatment of multiple advanced solid tumors types.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 23, 2024
Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Repare Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Foundation Medicine Partners with Repare for Genomic Profiling and Companion Diagnostic
Details : The collaboration aims to support Repare’s ongoing clinical development of RP-6306 (lunresertib) oral small molecule inhibitor of PKMYT1 alone or with camonsertib for the treatment of neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 12, 2024
Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Repare Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Repare Therapeutics Doses First Patient in Camonsertib NSCLC Trial
Details : RP-3500 (camonsertib), a potential best-in-class oral small molecule inhibitor of ATR (Ataxia-Telangiectasia and Rad3-related protein kinase). It is evaluated for non-small cell lung cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 10, 2024
Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Repare's Lunresertib Gets FDA Fast Track for Platinum-Resistant Ovarian Cancer
Details : FDA granted Fast Track designation to RP-6306 (lunresertib) in combination with RP-3500 (camonsertib) for CCNE1 amplified, or FBXW7 or PPP2R1A-mutated platinum-resistant ovarian cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 04, 2024
Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,325.0 million
Deal Type : Termination
Repare Therapeutics to Regain Global Rights to Camonsertib
Details : Repare regains global rights to RP-3500 (camonsertib), a potential best-in-class ATR inhibitor, after a termination of a partnership.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $125.0 million
February 12, 2024
Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,325.0 million
Deal Type : Termination

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Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,338.6 million
Deal Type : Licensing Agreement
Repare Therapeutics Announces Achievement of $40 Million Roche Clinical Milestone Payment
Details : Roche is responsible for developing RP-3500/RG6526 (camonsertib), a selective oral small molecule inhibitor of ATR for treating tumors with synthetic-lethal genomic alterations.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $125.0 million
January 25, 2024
Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,338.6 million
Deal Type : Licensing Agreement

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Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Repare Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer
Details : RP-3500 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 04, 2022
Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Repare Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Repare Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RP-3500 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Leukemia, Lymphocytic, Chronic, B-Cell.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 06, 2022
Lead Product(s) : Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Repare Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
