
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Discovery Platform
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : Undisclosed
Deal Type : Collaboration
Bit.Bio Announces First Project with The Michael J. Fox Foundation for Parkinson’s
Details : The collaboration with MJFF leverages bit.bio’s discovery platform and opti-ox technology for reprogramming iPSCs into functional human cells for research in Parkinson’s disease.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
March 05, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Discovery Platform
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Allogeneic Induced Hepatocyte-Like Cell
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : bbHEP01 is a encapsulated allogeneic txHepatocytes for the treatment of acute liver failure, expected to enter clinical development in 2025 and generate initial clinical data in 2026.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
November 08, 2023
Lead Product(s) : Allogeneic Induced Hepatocyte-Like Cell
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Study Phase : Discovery Platform
Sponsor : BlueRock Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the agreement, bit.bio will use its machine learning powered discovery platform to identify transcription factor combinations for reprogramming iPSCs into Tregs, for the discovery and manufacture of iPSC-derived regulatory T cells for use in creati...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
August 03, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Highest Development Status : Discovery Platform
Sponsor : BlueRock Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The disease models, ioSkeletal Myocytes DMD Exon 44 Deletion™ and ioSkeletal Myocytes DMD Exon 52 Deletion™, are designed to advance the discovery and development of treatments for Duchenne muscular dystrophy (DMD).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
July 12, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : ioGlutamatergic Neurons(MAPT N279K/WT™) Human iPSC-derived FTD disease model,A rapidly maturing, consistent and scalable isogenic system to study frontotemporal dementia (FTD).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
November 23, 2022

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Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Discovery
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
bit.bio Presents Data at ISSCR Demonstrating Their Platform Capability to Create Any Human Cell
Details : These precisely reprogrammed cell types are generated with the company’s precision cellular reprogramming technology opti-oxTM that enables unlimited batches of any human cell to be manufactured consistently at scale.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
June 16, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Discovery
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Bit.bio Launches Huntington’s Disease Human Cell Model
Details : First neurodegenerative disease model launched from bit.bio's new ioDisease Model portfolio. Accurately replicates Huntington's disease genotype in human cells, setting a new standard in cell models for drug discovery.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 09, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

bit.bio Raises in Excess of $100 Million in First Close of Series B Financing
Details : The funding will accelerate the clinical development of the proprietary cell coding technology opti-ox - a breakthrough gene engineering approach that enables unlimited batches of human cell to be manufactured consistently at scale through direct reprogr...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
November 05, 2021
