[{"orgOrder":0,"company":"Medivir","sponsor":"IGM Biosciences","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWEDEN","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Birinapant","moa":"||SMAC","graph1":"Oncology","graph2":"Phase I","graph3":"Medivir","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Medivir \/ IGM Biosciences","highestDevelopmentStatusID":"6","companyTruncated":"Medivir \/ IGM Biosciences"},{"orgOrder":0,"company":"Medivir","sponsor":"IGM Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWEDEN","productType":"Other Small Molecule","year":"2021","type":"Licensing Agreement","leadProduct":"Birinapant","moa":"||SMAC","graph1":"Oncology","graph2":"Phase I","graph3":"Medivir","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Medivir \/ IGM Biosciences","highestDevelopmentStatusID":"6","companyTruncated":"Medivir \/ IGM Biosciences"},{"orgOrder":0,"company":"TetraLogic Pharmaceuticals","sponsor":"Medivir","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Birinapant","moa":"SMAC","graph1":"Oncology","graph2":"Phase I","graph3":"TetraLogic Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"TetraLogic Pharmaceuticals \/ Medivir","highestDevelopmentStatusID":"6","companyTruncated":"TetraLogic Pharmaceuticals \/ Medivir"}]

Find Clinical Drug Pipeline Developments & Deals for Birinapant

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                          Top Deals by Deal Size (USD bn)

                          01

                          Specialty & Agro Chemical
                          Not Confirmed
                          Specialty & Agro Chemical
                          Not Confirmed

                          Details : IGM will receive global, exclusive development and commercialization rights for birinapant, a clinical-stage SMAC mimetic that binds to and degrades Inhibitors of Apoptosis Proteins (IAPs), leading to cell death (apoptosis) in tumor cells.

                          Product Name : TL32711

                          Product Type : Other Small Molecule

                          Upfront Cash : $1.0 million

                          November 01, 2021

                          Lead Product(s) : Birinapant,IGM-8444

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : IGM Biosciences

                          Deal Size : $352.5 million

                          Deal Type : Licensing Agreement

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                          02

                          Specialty & Agro Chemical
                          Not Confirmed
                          Specialty & Agro Chemical
                          Not Confirmed

                          Details : Company initiated its clinical study in solid cancers with birinapant (IGM-9427) in combination with IGM’s DR5 agonist antibody IGM-8444. The purpose of this first clinical trial with the combination will be to explore safety and tolerability.

                          Product Name : TL32711

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 11, 2021

                          Lead Product(s) : Birinapant,IGM-8444

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : IGM Biosciences

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          TetraLogic Pharmaceuticals

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                          Specialty & Agro Chemical
                          Not Confirmed

                          TetraLogic Pharmaceuticals

                          Country arrow
                          Specialty & Agro Chemical
                          Not Confirmed

                          Details : The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to TetraLogic if and when Medivir develops, markets or out-licenses birinapant further.

                          Product Name : TL32711

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 12, 2020

                          Lead Product(s) : Birinapant

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Medivir

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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