Lead Product(s) : Birinapant,IGM-8444
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : IGM Biosciences
Deal Size : $352.5 million
Deal Type : Licensing Agreement
IGM Biosciences Enters into Exclusive Licensing Agreement with Medivir for Birinapant
Details : IGM will receive global, exclusive development and commercialization rights for birinapant, a clinical-stage SMAC mimetic that binds to and degrades Inhibitors of Apoptosis Proteins (IAPs), leading to cell death (apoptosis) in tumor cells.
Product Name : TL32711
Product Type : Other Small Molecule
Upfront Cash : $1.0 million
November 01, 2021
Lead Product(s) : Birinapant,IGM-8444
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : IGM Biosciences
Deal Size : $352.5 million
Deal Type : Licensing Agreement
Lead Product(s) : Birinapant,IGM-8444
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : IGM Biosciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Birinapant Clinical Study Initiated By IGM Biosciences
Details : Company initiated its clinical study in solid cancers with birinapant (IGM-9427) in combination with IGM’s DR5 agonist antibody IGM-8444. The purpose of this first clinical trial with the combination will be to explore safety and tolerability.
Product Name : TL32711
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 11, 2021
Lead Product(s) : Birinapant,IGM-8444
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : IGM Biosciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Birinapant
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Medivir
Deal Size : Undisclosed
Deal Type : Agreement
Details : The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to TetraLogic if and when Medivir develops, markets or out-licenses birinapant further.
Product Name : TL32711
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 12, 2020
Lead Product(s) : Birinapant
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Medivir
Deal Size : Undisclosed
Deal Type : Agreement