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    [{"orgOrder":0,"company":"Astex Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Beroterkib","moa":"ERK||Extracellular signal-regulated kinase 1 (ERK1)","graph1":"Undisclosed","graph2":"Phase I","graph3":"Astex Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Astex Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Astex Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Astex Pharmaceuticals","sponsor":"Mosaic Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Licensing Agreement","leadProduct":"Beroterkib","moa":"ERK","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Astex Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Astex Pharmaceuticals \/ Mosaic Therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"Astex Pharmaceuticals \/ Mosaic Therapeutics"}]

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                            01

                            Astex Pharmaceuticals

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                            Astex Pharmaceuticals

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                            Lead Product(s) : Beroterkib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Mosaic Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            Mosaic in-Licenses Two Oncology Programs from Astex for Combination Therapies

                            Details : Under the licensing agreement, Mosaic hold the rights of two clinical programs, which includes ASTX029 (beroterkib). It is being evaluated fr the treatment of neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            April 24, 2025

                            Lead Product(s) : Beroterkib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Mosaic Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            Astex Pharmaceuticals

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                            The MedTech Conference
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                            Astex Pharmaceuticals

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                            Lead Product(s) : Beroterkib

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Phase 1 Study to Evaluate the Effect of Food on Pharmacokinetics of ASTX029

                            Details : Astx029 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 10, 2020

                            Lead Product(s) : Beroterkib

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Taiho Oncology

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                            Taiho Oncology

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                            Lead Product(s) : Beroterkib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Study of ASTX029 in Subjects With Advanced Solid Tumors

                            Details : Astx029 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 09, 2018

                            Lead Product(s) : Beroterkib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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