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    [{"orgOrder":0,"company":"AVM Biotechnology","sponsor":"Medpace, Inc","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Steroid","year":"2020","type":"Inapplicable","leadProduct":"AVM0703","moa":"Glucocorticoid receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"AVM Biotechnology","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"AVM Biotechnology \/ Medpace, Inc","highestDevelopmentStatusID":"7","companyTruncated":"AVM Biotechnology \/ Medpace, Inc"},{"orgOrder":0,"company":"AVM Biotechnology","sponsor":"Medpace, Inc","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Steroid","year":"2020","type":"Inapplicable","leadProduct":"AVM0703","moa":"Glucocorticoid receptor","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase I","graph3":"AVM 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Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"AVM Biotechnology \/ Undisclosed"},{"orgOrder":0,"company":"AVM Biotechnology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Steroid","year":"2022","type":"Inapplicable","leadProduct":"Dexamethasone Sodium Phosphate","moa":"Glucocorticoid receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"AVM Biotechnology","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"AVM Biotechnology \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"AVM Biotechnology \/ Undisclosed"},{"orgOrder":0,"company":"AVM Biotechnology","sponsor":"National Institute of Diabetes and Digestive Kidney 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    Find Clinical Drug Pipeline Developments & Deals by AVM Biotechnology

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                            01

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : AVM0703

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients

                            Details : AVM0703 is a Steroid drug candidate, which is currently being evaluated in clinical studies for the treatment of Glioblastoma.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            August 03, 2023

                            Lead Product(s) : AVM0703

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AVM Biotechnology Announces Twenty-Eight (28) Solid Tumor and Blood Cancer Patients Have Been Treated with Imm...

                            Details : AVM0703 is small molecule immunomodulatory drug enrolling Phase 2 trials in US in relapsed/refractory Non-Hodgkin's Lymphoma (NHL) which began enrollment Q3 2023 (partially funded by NCI Ph II FastTrak grant 1R44CA272096).

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            August 01, 2023

                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : The Division of Cancer Treatment and Diagnosis

                            Deal Size : $2.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            AVM Biotechnology Awarded $2 Million National Cancer Institute SBIR Phase II Grant from the National Institute...

                            Details : AVM0703 (Dexamethasone sodium phosphate) is a small molecule which triggers the production and release of endogenous bispecific gamma delta TCR+ invariant TCR+ Natural Killer T-like cells (AVM-NKT).

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Undisclosed

                            June 14, 2022

                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : The Division of Cancer Treatment and Diagnosis

                            Deal Size : $2.0 million

                            Deal Type : Funding

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                            04

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AVM Biotechnology to Present Poster Highlighting the Effects of AVM0703 Against Solid Tumors and Blood Cancers...

                            Details : AVM0703 (dexamethasone) led to, complete response in 27% of immune-resistant mouse A20 tumors as monotherapy and complete response in 60% when combined with 2 doses of cyclophosphamide/fludarabine (CyFlu).

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            June 01, 2022

                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AVM Biotechnology Founder and CSO to Present Company Information and Clinical Trial Progress at Life Science I...

                            Details : AVM0703 is a small molecule which triggers the production and release of endogenous bispecific gamma delta TCR+ and invariant TCR+ Natural Killer T-like cells (AVM-NKT).

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            April 19, 2022

                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Sponsor : National Institute of Diabetes and Digestive Kidney Disease

                            Deal Size : $1.6 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            AVM Biotechnology Awarded $1.6 Million Phase II SBIR Grant to Study AVM0703’s Potential to Reverse Type 1 Di...

                            Details : T1D is an autoimmune disease that destroys beta cells, the insulin-making cells in the pancreas. This award provides an endorsement of AVM0703’s potential in two distinct and crucial therapeutic areas, diabetes and cancer.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Undisclosed

                            April 05, 2022

                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Sponsor : National Institute of Diabetes and Digestive Kidney Disease

                            Deal Size : $1.6 million

                            Deal Type : Funding

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                            07

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Seattle AVM Biotechnology Announces Second IND for AVM0703

                            Details : This second study will evaluate AVM0703 in two different ARDS patient populations: one with COVID-19-mediated moderate to severe ARDS and the other with Influenza-mediated severe ARDS.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            September 16, 2020

                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            AVM Biotechnology

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Dexamethasone Sodium Phosphate,Hydrocortisone,Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AVM Biotechnology Awarded SBIR Phase I Grant from National Cancer Institute

                            Details : AVM Biotechnology has been awarded a National Cancer Institute Small Business Innovation Research Grant from the NIH to study the use of AVM0703 as a preconditioning agent to allow safe and efficient delivery of therapeutic immune cells for cancer treatm...

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            June 11, 2020

                            Lead Product(s) : Dexamethasone Sodium Phosphate,Hydrocortisone,Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : AVM0703

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase I

                            Sponsor : Medpace, Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS

                            Details : AVM0703 is a Steroid drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Respiratory Distress Syndrome.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            April 28, 2020

                            Lead Product(s) : AVM0703

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase I

                            Sponsor : Medpace, Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            AVM Biotechnology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            AVM Biotechnology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AVM Biotechnology has FDA Approval for Clinical Trials for Promising New Cancer Treatment

                            Details : AVM Biotechnology received clinical trial approval for AVM0703. Unlike chemotherapy and radiation, AVM0703 spares platelets and red blood cells, limiting the need for transfusions.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            April 14, 2020

                            Lead Product(s) : Dexamethasone Sodium Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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