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                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Merck Group | Astellas Pharma | University Hospital Tübingen

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                            Deal Type : Inapplicable

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                            Enfortumab Vedotin + Avelumab Safety and Efficacy In Advanced Penile Cancer

                            Details : Avelumab is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Penile Squamous Cell Carcinoma.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            August 07, 2025

                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Merck Group | Astellas Pharma | University Hospital Tübingen

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Vaximm AG

                            Switzerland arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            Vaximm AG

                            Switzerland arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : VXM01,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Merck Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vaximm Shares VXM01-Avelumab Combo Results in Glioblastoma

                            Details : VXM01 is an investigational oral anti-VEGFR-2 vaccine, which is being evaluated in combination with avelumab (PD-L1 inhibitor) for treating patients with recurrent glioblastoma.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            March 26, 2025

                            Lead Product(s) : VXM01,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Merck Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Mirror Biologics

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                            AIChE Annual Meeting
                            Not Confirmed

                            Mirror Biologics

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : AlloStim,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Merck Group

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Mirror Biologics, Merck KGaA Collaborate on Metastatic Colorectal Cancer

                            Details : The collaboration aims to conduct a Phase II to evaluate the combination of an experimental immunotherapy drug, AlloStim, and an immune checkpoint inhibitor, Bavencio avelumab from Merck.

                            Product Name : AlloStim

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            January 08, 2025

                            Lead Product(s) : AlloStim,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Merck Group

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            Ionctura

                            Switzerland arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            Ionctura

                            Switzerland arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Roginolisib,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            iOnctura Reaches New Clinical Milestones in Uveal Melanoma

                            Details : IOA-244 (roginolisib) is a first-in-class small molecule allosteric modulator of PI3Kδ. It is being evaluated for the treatment of cutaneous melanoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 11, 2024

                            Lead Product(s) : Roginolisib,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Aulos

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            Aulos

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : AU-007,Aldesleukin,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aulos Bio Doses First Patient in Phase 2 Trial of Avelumab and AU-007 in Lung Cancer

                            Details : AU-007 is a human IgG1 monoclonal antibody designed to harness the power of interleukin-2 (IL-2) to eradicate solid tumors. It is being evaluated for the treatment of non-small cell lung cancer.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            November 27, 2024

                            Lead Product(s) : AU-007,Aldesleukin,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            GORTEC

                            Country arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            GORTEC

                            Country arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of TPEx Followed by a Maintenance With Avelumab and Cetuximab in First Line Recurrent or Metastatic Squa...

                            Details : Avelumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Squamous Cell Carcinoma of Head and Neck.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            October 15, 2024

                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Transgene

                            France arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            Transgene

                            France arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Transgene's Viral Cancer Vaccine Flunks Midphase Test

                            Details : TG4001 in combination with avelumab versus avelumab alone is being investigated in patients with recurrent or metastatic HPV16-positive cervical and anogenital tumors.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            October 14, 2024

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            EMD Serono

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            EMD Serono

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Panagiotis Konstantinopoulos, MD, PhD

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Avelumab and M1774 in ARID1A-mutated Endometrial Cancer (Prior IO)

                            Details : Avelumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Endometrial Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            July 24, 2024

                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Panagiotis Konstantinopoulos, MD, PhD

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            EMD Serono

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            EMD Serono

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Merck Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior ...

                            Details : Avelumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Carcinoma, Transitional Cell.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            May 22, 2024

                            Lead Product(s) : Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Merck Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Immutep

                            Australia arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            Immutep

                            Australia arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Eftilagimod Alpha,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Merck Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First Patient Dosed in Efti and BAVENCIO® Trial for Urothelial Cancer

                            Details : Efti (eftilagimod alpha) is being evaluated in phase 1 trials with Bavencio (avelumab) for patients with metastatic urothelial carcinoma.

                            Product Name : Efti

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            January 04, 2024

                            Lead Product(s) : Eftilagimod Alpha,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Merck Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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