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Find Clinical Drug Pipeline Developments & Deals for Avdoralimab

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                          01

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : Avdoralimab (IPH5401) is a therapeutic antibody that specifically binds and blocks C5a receptors (C5aR1) expressed on subsets of myeloid-derived suppressor cells (MDSC) and neutrophils.

                          Product Name : IPH5401

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          June 07, 2021

                          Lead Product(s) : Avdoralimab

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : The study found that patients who progress towards severe COVID-19 disease, including those with severe pneumonia and acute respiratory distress syndrome (ARDS), exhibit an activation of the C5a/C5aR1 pathway.

                          Product Name : IPH5401

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          July 29, 2020

                          Lead Product(s) : Avdoralimab

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : First patient was dosed in a randomized, double-blind Phase II clinical trial, evaluating the safety and efficacy of its anti-C5aR antibody, avdoralimab (IPH5401), in COVID-19 patients.

                          Product Name : IPH5401

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 28, 2020

                          Lead Product(s) : Avdoralimab

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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