Lead Product(s) : KUR-501,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : SVB Securities
Deal Size : $30.0 million
Deal Type : Public Offering
Athenex, Inc. Announces Pricing of $30 Million Public Offering of Common Stock and Warrants
Details : Athenex intends to use the net proceeds from the proposed offering to fund ongoing clinical development for its product candidates and for working capital and other general corporate purposes.
Product Name : KUR-501
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 08, 2022
Lead Product(s) : KUR-501,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : SVB Securities
Deal Size : $30.0 million
Deal Type : Public Offering
Lead Product(s) : Paclitaxel,Dostarlimab,Encequidar
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The publication of phase 3 data, which show that oral Taxol (paclitaxel) plus encequidar significantly improves tumor response in patients with metastatic breast cancer, compared to IV administration.
Product Name : Oraxol
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
July 25, 2022
Lead Product(s) : Paclitaxel,Dostarlimab,Encequidar
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Paclitaxel,Encequidar,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The agreement will support the expansion phase of the trial to further investigate the preliminary encouraging results of the KX-ORAX-011 Phase 1 clinical trial evaluating Oraxol (encequidar plus oral paclitaxel) in combination with pembrolizumab for cer...
Product Name : Oraxol
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
May 16, 2022
Lead Product(s) : Paclitaxel,Encequidar,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : KUR-502,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Encouraging data from interim update of the ANCHOR study support the promising efficacy and favorable safety profile of KUR-502 in heavily pretreated patients with hematological malignancies.
Product Name : KUR-502
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 25, 2022
Lead Product(s) : KUR-502,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : KUR-501,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : KUR-501, is an autologous NKT cell CAR product that targets GD2, data demonstrate expansion of CAR-NKT cells post-transfer in all patients, and objective responses in patients with relapsed/refractory neuroblastoma.
Product Name : KUR-501
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 05, 2022
Lead Product(s) : KUR-501,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Paclitaxel,Encequidar
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Post hoc analysis of this subgroup of patients with hepatic impairment was conducted and showed a median survival rate of 18.9 months in patients treated with Oral Paclitaxel.
Product Name : Oraxol
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
November 22, 2021
Lead Product(s) : Paclitaxel,Encequidar
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Paclitaxel,Encequidar,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Athenex Presents Data from Oral Paclitaxel + Pembrolizumab Phase 1 Study at ESMO 2021
Details : The primary objective for dose escalation phase of the study was to determine the maximum tolerated dose (MTD) and identify the recommended Phase 2 dose (RP2D) of Oraxol (Oral Paclitaxel + Encequidar) in combination with pembrolizumab in patients with ad...
Product Name : Oraxol
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
September 16, 2021
Lead Product(s) : Paclitaxel,Encequidar,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : The Division of Cancer Treatment and Diagnosis
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Athenex is granted worldwide rights to the development, manufacturing, and commercialization of allogeneic NKT products engineered via viral and non-viral means, and autologous T cell therapy products.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 11, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : The Division of Cancer Treatment and Diagnosis
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : KUR-502,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Updated data show continued favorable safety profile and encouraging anti-tumor activity in adult patients of in B-cell relapsed/refractory non-Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL) treated with low doses of KUR-502 (Allogeneic CD...
Product Name : KUR-502
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 11, 2021
Lead Product(s) : KUR-502,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Paclitaxel,Encequidar
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In the CRL, the FDA indicated its concern of safety risk to patients in terms of an increase in neutropenia-related sequelae on the Oral Paclitaxel arm compared with the IV paclitaxel arm.
Product Name : Oraxol
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
January 03, 2021
Lead Product(s) : Paclitaxel,Encequidar
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable