

Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Ambrisentan
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome
Details : Ambrisentan is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Hepatorenal Syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 13, 2024
Lead Product(s) : Ambrisentan
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Rodatristat Ethyl,Ambrisentan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RVT-1201 (rodatristat ethyl) is a tryptophan hydroxylase inhibitor designed to reduce body’s peripheral production of serotonin, in preclinical study comparing rodatristat ethyl monotherapy and in combination with ambrisentan, in an animal model of PAH...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 06, 2022
Lead Product(s) : Rodatristat Ethyl,Ambrisentan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ambrisentan
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ambrisentan is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of COVID-19.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 25, 2021
Lead Product(s) : Ambrisentan
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Ambrisentan
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Rambam Health Care Campus
Deal Size : Inapplicable
Deal Type : Inapplicable
Effects of Endothelin Receptor Antagonist on Ischemic Kidney Injury During Nephron Sparing Surgery
Details : Ambrisentan is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Acute Kidney Injury.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 29, 2020
Lead Product(s) : Ambrisentan
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Rambam Health Care Campus
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : EDP1815,Ambrisentan,Dapagliflozin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Evelo Biosciences announces EDP1815 to advance into phase 2/3 TACTIC-E COVID-19 trial
Details : EDP1815 will be included in the TACTIC-E clinical trial. The trial will evaluate the safety and efficacy of certain experimental therapies in the prevention and treatment of life-threatening complications associated with COVID-19 in hospitalized patients...
Product Name : Undisclosed
Product Type : Microorganism
Upfront Cash : Inapplicable
June 22, 2020
Lead Product(s) : EDP1815,Ambrisentan,Dapagliflozin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Dapagliflozin,Ambrisentan
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cambridge Launches Fast-Turnaround Experimental Drug Trial to Treat Covid-19
Details : The newly launched trial, known as TACTIC-E (the “E” stands for “experimental”), has been designed to test drugs that have been specifically developed to treat Covid-19 as well as investigating whether combinations of drugs that are already in us...
Product Name : Forxiga
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 22, 2020
Lead Product(s) : Dapagliflozin,Ambrisentan
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ambrisentan
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ambrisentan is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Fibrosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 01, 2019
Lead Product(s) : Ambrisentan
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Ambrisentan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase IV
Sponsor : Gilead Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ambrisentan is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hypertension, Portopulmonary.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 13, 2017
Lead Product(s) : Ambrisentan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase IV
Sponsor : Gilead Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Ambrisentan
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Gilead Sciences | National Heart, Lung, and Blood Institute
Deal Size : Inapplicable
Deal Type : Inapplicable
The Role of Endothelin-1 in Sickle Cell Disease
Details : Ambrisentan is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Anemia, Sickle Cell.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 18, 2016
Lead Product(s) : Ambrisentan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Gilead Sciences | National Heart, Lung, and Blood Institute
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ambrisentan
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Covance Harrogate | Hammersmith Medicines Research
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ambrisentan is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hypertension, Pulmonary.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 23, 2016
Lead Product(s) : Ambrisentan
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Covance Harrogate | Hammersmith Medicines Research
Deal Size : Inapplicable
Deal Type : Inapplicable
