
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Kalaris Announces Closing of Merger with AlloVir
Details : The combined company will focus on the development of TH103, a fully humanized, recombinant fusion protein, for patients with neovascular age-related macular degeneration.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
March 18, 2025
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
AlloVir & Kalaris Merge, Focus on Retinal Disease Therapies
Details : The combined company will focus on the development of TH103, a fully humanized, recombinant fusion protein, for patients with neovascular age-related macular degeneration.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
November 08, 2024
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ALVR105 (posoleucel) is a T-lymphocyte cell therapy which is under phase 3 clinical development for the treatment of adenovirus infections, BK virus infections & Epstein-Barr virus infection.
Product Name : Viralym-M
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
December 22, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : J.P. Morgan
Deal Size : $7.5 million
Deal Type : Public Offering
AlloVir Announces Pricing of Public Offering of Common Stock
Details : The company intends to use the net proceeds to complete enrollment and achieve data readouts in all three of its ongoing Phase 3 trials of its lead multi-virus specific candidate, Viralym-M (posoleucel), an allogeneic, off-the-shelf multi-virus specific ...
Product Name : Viralym-M
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
June 21, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : J.P. Morgan
Deal Size : $7.5 million
Deal Type : Public Offering

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Viralym-M (posoleucel) is a multi-virus specific T cell therapy (VST) targeting five viral pathogens ((BKV), (CMV), (AdV), (EBV), HHV-6). It is designed to play an important role in providing bridging immunity between conditioning and reconstitution of t...
Product Name : Viralym-M
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
February 15, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
AlloVir Announces Plans to Complete Enrollment in Three Phase 3 Posoleucel Studies in 2023
Details : Viralym-M (posoleucel) is a multi-virus specific T cell therapy (VST) targeting five viral pathogens ((BKV), (CMV), (AdV), (EBV), HHV-6). It is designed to play an important role in providing bridging immunity between conditioning and reconstitution of t...
Product Name : Viralym-M
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
January 09, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Kite Pharma
Deal Size : $126.6 million
Deal Type : Public Offering
AlloVir Announces $126.6 Million Registered Direct Offering
Details : AlloVir intends to use the net proceeds from the offering, to complete enrollment and achieve data readouts in all three of the Company’s ongoing Phase 3 trials of its lead multi-virus specific T-cell therapy candidate, posoleucel (Viralym-M).
Product Name : Viralym-M
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
July 27, 2022
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Kite Pharma
Deal Size : $126.6 million
Deal Type : Public Offering

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AlloVir’s lead product, posoleucel (Viralym-M, ALVR105), is in late-stage clinical development as an allogeneic, off-the-shelf, multi-virus-specific T cell therapy targeting six viral pathogens in immunocompromised individuals.
Product Name : Viralym-M
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
June 07, 2022
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The new RMAT designation was based on initial data from an open-label Phase 2 study evaluating the potential for posoleucel to prevent life-threatening infections from six common viruses following allo-HCT.
Product Name : Viralym-M
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
April 20, 2022
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Posoleucel is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase II/ phase III clinical studies for the treatment of Adenoviridae Infections.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
March 31, 2022
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
