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Wainwright & Co","pharmaFlowCategory":"D","amount":"$3.5 million","upfrontCash":"Undisclosed","newsHeadline":"Adial Pharmaceuticals Announces Exercise of Warrants for $3.5 Million Gross Proceeds","therapeuticArea":"Psychiatry\/Psychology","highestDevelopmentStatus":"Phase III","country":"","productType":"Small molecule","productStatus":"New Molecular Entity","date":"March 2024","year":"2024","type":"Public Offering","leadProduct":"Ondansetron","moa":"","url1":"","url2":"","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Adial Pharmaceuticals","amount2":0,"therapeuticAreaNew":"Psychiatry\/Psychology","highestDevelopmentStatusNew":"Phase III","highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","productSubType":"Small molecule","amount2New":0,"dosageForm":"","sponsorNew":"Adial Pharmaceuticals \/ H.C. 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Find Clinical Drug Pipeline Developments & Deals by Adial Pharmaceuticals

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : AD04 (ondansetron) is an investigational - genetically targeted serotonin-3 receptor antagonist, which is being evaluated for the treatment of Alcohol Use Disorder.

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 23, 2024

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : AD04 (ondansetron) is an investigational - genetically targeted serotonin-3 receptor antagonist, which is being evaluated for the treatment of Alcohol Use Disorder.

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 05, 2024

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : The net proceeds will be used in the clinical development of AD04 (ondansetron), which is a Serotonin 5-HT3a receptor antagonist. It is being evaluated in the clinical trial studies for patients with alco...

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 01, 2024

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : H.C. Wainwright & Co

                          Deal Size : $3.5 million

                          Deal Type : Public Offering

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                          04

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : The Company intends to use the net proceeds to support regulatory and clinical activities related to AD04 (ondansetron), a genetically targeted, serotonin-3 receptor antagonist, its lead investigational d...

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 24, 2023

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : H.C. Wainwright & Co.

                          Deal Size : $4.0 million

                          Deal Type : Private Placement

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                          05

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : The Company intends to use the net proceeds to support regulatory and clinical activities related to AD04 (ondansetron), a genetically targeted, serotonin-3 receptor antagonist, its lead investigational d...

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 20, 2023

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : H.C. Wainwright & Co.

                          Deal Size : $4.0 million

                          Deal Type : Private Placement

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                          06

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : The Company’s lead investigational new drug product, AD04 (ondansetron), is a genetically targeted, serotonin-3 receptor antagonist, therapeutic agent for the treatment of Alcohol Use Disorder (AUD) in ...

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 01, 2023

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : Adenomed

                          Deal Size : $83.0 million

                          Deal Type : Divestment

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                          07

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Lead Product(s) : PNV-5030

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : At 30 minutes post dose, PNV-5030 reduced pain by 43% compared to the control group, while acetaminophen doses did not have a significant effect. PNV-5030 also demonstrated a 49% improvement in pain reduc...

                          Product Name : PNV-5030

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 26, 2022

                          Lead Product(s) : PNV-5030

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Lead Product(s) : PNV-6005

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Preclinical

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : In the study, PNV-6005 demonstrated statistically significant effect against both primary study endpoints, which are pre-clinical endpoints expected to indicate potential efficacy against ulcerative colit...

                          Product Name : PNV-6005

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 06, 2022

                          Lead Product(s) : PNV-6005

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Preclinical

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : AD04 (ondansetron) achieved statistically significant mean reduction in heavy drinking days among pre-specified group of heavy drinkers, compared to placebo, with an approximately 79% reduction from basel...

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 20, 2022

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Boulder Peptide 2024
                          Not Confirmed
                          Boulder Peptide 2024
                          Not Confirmed

                          Details : In studies of Zofran, patients were given AD04 (ondansetron) acutely at dosages up to almost 100 times dosage expected to be formulated in AD04 with the highest doses of Zofran® given intravenously which...

                          Product Name : AD04

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 18, 2022

                          Lead Product(s) : Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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