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Find Clinical Drug Pipeline Developments & Deals by Adaptive Phage Therapeutics

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                          Therapeutic Area by Lead Product

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                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : The combined company will advance its pipeline with two Phase 2 assets, BX004 for chronic pulmonary infections in cystic fibrosis patients, and BX211 for diabetic foot osteomyelitis.

                          Product Name : BX004

                          Product Type : Microorganism

                          Upfront Cash : Undisclosed

                          June 03, 2024

                          Lead Product(s) : BX004

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : BiomX

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          02

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : The combined company will advance its pipeline with two Phase 2 assets, BX004 for chronic pulmonary infections in cystic fibrosis patients, and BX211 for diabetic foot osteomyelitis.

                          Product Name : BX004

                          Product Type : Microorganism

                          Upfront Cash : Undisclosed

                          March 18, 2024

                          Lead Product(s) : BX004

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : BiomX

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          03

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : The investigational phage therapeutic, WRAIR-PAM-CF1, was developed by the Walter Reed Army Institute of Research (WRAIR) and is licensed to and manufactured by APT. The trial is expected to enroll a total of 72 patients at multiple sites across the coun...

                          Product Name : WRAIR_PAM-CF1

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          December 01, 2023

                          Lead Product(s) : WRAIR_EPa11,WRAIR_EPa39,WRAIR_EPa83

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : The financing will be used in continuing clinical progression of APT’s pipeline of bacteriophage-based therapies that specifically target and kill bacteria, to create personalized treatments for patients with difficult-to-treat AMR infections.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $12.0 million

                          June 13, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Deerfield Management

                          Deal Size : $24.0 million

                          Deal Type : Series B Financing

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                          05

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : Under the agreement, Hadasit and Yissum grants APT exclusive rights to make, use, and sell licensed phages for human bacteriophage-based therapy, with the right to sublicense through multiple tiers.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          May 24, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Undisclosed

                          Sponsor : Israeli Phage Therapy Center

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : Phages from the APT phage bank (Phage-based Therapy) are precision-matched to the patient’s infections through a proprietary phage susceptibility test (PST) that APT has teamed with Mayo Clinic Laboratories to commercialize on a global scale.

                          Product Name : PhageBank

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          May 17, 2022

                          Lead Product(s) : PhageBank

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : Proceeds of the AMR Action Fund’s investment are primarily intended to support APT’s clinical trials to address substantial unmet patient needs in Prosthetic Joint Infection (PJI) and Diabetic Foot Osteomyelitis (DFO).

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 04, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Deerfield Management

                          Deal Size : $61.0 million

                          Deal Type : Series B Financing

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                          08

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : APT’s PhageBank™ technology is a growing collection of hundreds of bacteriophage, collectively providing broad spectrum coverage against six of the highest priority multi-drug resistant bacterial pathogens.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          November 05, 2021

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Deerfield Management

                          Deal Size : $40.8 million

                          Deal Type : Series B Financing

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                          09

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : Funding will support the PhageBank™ platform to treat drug-resistant infections across multiple indications which leverages an ever-expanding library of bacteriophage (phage) that collectively provide evergreen broad spectrum and polymicrobial coverage...

                          Product Name : PhageBank

                          Product Type : Microorganism

                          Upfront Cash : Undisclosed

                          September 30, 2021

                          Lead Product(s) : PhageBank

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : US Department of Defense

                          Deal Size : $31.2 million

                          Deal Type : Funding

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                          10

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : In-vitro activity of multiple phage strain candidates were assessed by means of APT’s PhageBank™ Susceptibility Test (PST) to determine the clinically relevant selection.

                          Product Name : PhageBank

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          September 09, 2021

                          Lead Product(s) : PhageBank

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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