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    [{"orgOrder":0,"company":"Adamas Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Amantadine Hydrochloride","moa":"Glutamate [NMDA] receptor | Matrix protein 2","graph1":"Neurology","graph2":"Approved FDF","graph3":"Adamas Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule, Extended Release","sponsorNew":"Adamas Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Adamas Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Adamas Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Amantadine Hydrochloride","moa":"Glutamate [NMDA] receptor 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receptor | Matrix protein 2","graph1":"Neurology","graph2":"Approved FDF","graph3":"Adamas Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Tablet, Extended Release","sponsorNew":"Adamas Pharmaceuticals \/ Adamas Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Adamas Pharmaceuticals \/ Adamas Pharmaceuticals"},{"orgOrder":0,"company":"Adamas Pharmaceuticals","sponsor":"Osmotica Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Amantadine Hydrochloride","moa":"Glutamate [NMDA] receptor | Matrix protein 2","graph1":"Neurology","graph2":"Approved FDF","graph3":"Adamas Pharmaceuticals","amount2":0.01,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Oral Tablet, Extended Release","sponsorNew":"Adamas Pharmaceuticals \/ Adamas Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Adamas Pharmaceuticals \/ Adamas Pharmaceuticals"},{"orgOrder":0,"company":"Adamas Pharmaceuticals","sponsor":"Adamas Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Amantadine Hydrochloride","moa":"Matrix protein 2","graph1":"Neurology","graph2":"Phase IV","graph3":"Adamas Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Adamas Pharmaceuticals \/ Adamas Pharmaceuticals","highestDevelopmentStatusID":"11","companyTruncated":"Adamas Pharmaceuticals \/ Adamas Pharmaceuticals"}]

    Find Clinical Drug Pipeline Developments & Deals by Adamas Pharmaceuticals

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                            01

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Supernus Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Supernus Pharmaceuticals Completes Acquisition of Adamas Pharmaceuticals

                            Details : Acquistion will strengthens Parkinson’s disease portfolio with GOCOVRI (amantadine) extended release capsules, the first and only FDA-approved medicine indicated for the treatment of both OFF and dyskinesia in patients with Parkinson’s disease receiv...

                            Product Name : Gocovri

                            Product Type : Other Small Molecule

                            Upfront Cash : $450.0 million

                            November 24, 2021

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Supernus Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Acquisition

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                            02

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Supernus Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Supernus Pharmaceuticals to Acquire Adamas Pharmaceuticals Strengthening its CNS Product Portfolio

                            Details : The transaction will provide Supernus with two marketed products: GOCOVRI (amantadine) extended release capsules, indicated for both OFF and dyskinesia in patients with Parkinson’s disease and Osmolex ER (amantadine) tablets, approved for Parkinson’s...

                            Product Name : Gocovri

                            Product Type : Other Small Molecule

                            Upfront Cash : $450.0 million

                            November 10, 2021

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Supernus Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Acquisition

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                            03

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            New Data Analysis Supports GOCOVRI for Motor Complications for People With PD

                            Details : At week 12, participants treated with GOCOVRI reported statistically significant improvements in motor control for daily activities compared to placebo (least-squares mean changes from baseline of –3.4 points for GOCOVRI and –1.4 for placebo).

                            Product Name : Gocovri

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 06, 2021

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Recipient : Osmotica Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Adamas Completes Acquisition of OSMOLEX ER®

                            Details : Through this acquisition, OSMOLEX ER joins the Adamas portfolio which includes GOCOVRI® extended-release capsules for the treatment of dyskinesia in patients with Parkinson’s disease receiving levodopa-based therapy with or without concomitant dopamin...

                            Product Name : Osmolex ER

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 01, 2021

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Recipient : Osmotica Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            05

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Adamas Publishes New Data Analyses Demonstrating GOCOVRI Treatment More Than Doubled ON Time Without Dyskinesi...

                            Details : Patients enrolled in the pivotal trials increased daily ON time without dyskinesia by 2.9 hours with GOCOVRI compared to placebo, through the reduction of both OFF time and dyskinesia.

                            Product Name : Gocovri

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 29, 2021

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Phase IV

                            Recipient : Oregon Health and Science University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease

                            Details : Undisclosed

                            Product Name : Gocovri

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 14, 2020

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase IV

                            Recipient : Oregon Health and Science University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Adamas Announces FDA Filing Acceptance of sNDA to Modify Indication Statement for Gocovri

                            Details : Adamas has proposed to include GOCOVRI as an appropriate therapy for the treatment of OFF episodes in PD patients receiving levodopa. The clinical evidence supporting GOCOVRI’s effect on OFF time was demonstrated in two large pivotal Phase 3 trials.

                            Product Name : Gocovri

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 06, 2020

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Recipient : Osmotica Pharmaceuticals

                            Deal Size : $7.5 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Osmotica Pharmaceuticals plc Announces Agreement to Settle Patent Litigation with Adamas

                            Details : Under the terms of the agreement, both parties will drop their respective claims relating to the patent litigation, and Adamas will acquire the global rights to OSMOLEX ER for $7.5 million.

                            Product Name : Osmolex ER

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 12, 2020

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Recipient : Osmotica Pharmaceuticals

                            Deal Size : $7.5 million

                            Deal Type : Agreement

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                            09

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            June 25, 2018

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Adamas Pharmaceuticals

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                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety and Efficacy of ADS-5102 in Multiple Sclerosis Patients With Walking Impairment

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            February 19, 2018

                            Lead Product(s) : Amantadine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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