List of Suppliers' Co Processed Excipients Excipients Application used in Neomycin Sulfate on PharmaCompass.com

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ACTIVE PHARMA INGREDIENTS

23 API Suppliers, 11 USDMF, 5 CEP/COS, 2 JDMF, 1 KDMF, 22 NDC API, 10 VMF, 10 Listed Suppliers, $ API Reference Price

23 API Suppliers
11 USDMF
5 CEP/COS
2 JDMF
1 KDMF
22 NDC API
10 VMF
10 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

159 FDF Dossiers, 114 FDA Orange Book, 4 Europe, 7 Canada, 4 South Africa, 30 Listed Dossiers

159 FDF Dossiers
114 FDA Orange Book
4 Europe
7 Canada
4 South Africa
30 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG BASE/GM;10,000 UNITS/GM, OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM, CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/GM;10,000 UNITS/GM, SUSPENSION/DROPS;OTIC - EQ 3MG BASE/ML;10MG/ML;EQ 3.3MG BASE/ML;0.5MG/ML, OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

drugProductComposition
OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG BASE/GM;10,000 UNITS/GM
OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM
CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/GM;10,000 UNITS/GM
SUSPENSION/DROPS;OTIC - EQ 3MG BASE/ML;10MG/ML;EQ 3.3MG BASE/ML;0.5MG/ML
OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 6 SPI Pharma, 2 Seqens, 5 DKSH, 1 Jai Radhe Sales, 2 Nippon Fine Chemical, 4 Boai NKY Pharmaceuticals Ltd, 6 Gangwal Healthcare, 13 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 1 ACG Worldwide, 19 Actylis, 1 Aeon Procare, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 32 BASF, 10 Corel Pharma Chem, 3 DFE Pharma, 4 Finar, 10 Gangwal Chemicals, 4 Ideal Cures Pvt Ltd, 35 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 15 Microlex e.U, 2 Nanjing Bold Chemical, 2 Nomisma Healthcare, 2 Novo Excipients, 1 Pharmatrans-Sanaq, 4 Pluviaendo, 1 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 11 Roquette, 17 Seppic, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 3 Sigachi Industries, 2 The Dow Chemical Company, 2 Ulanqab Kema New Material, 1 Valens Pharmachem, 2 Vasa Pharmachem, 1 Zhejiang Huakang Pharmaceutical

relatedExcipients
1 Rochem International Inc
6 SPI Pharma
2 Seqens
5 DKSH
1 Jai Radhe Sales
2 Nippon Fine Chemical
4 Boai NKY Pharmaceuticals Ltd
6 Gangwal Healthcare
13 Nanjing Well Pharmaceutical
1 Pfanstiehl
1 ACG Worldwide
19 Actylis
1 Aeon Procare
4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
32 BASF
10 Corel Pharma Chem
3 DFE Pharma
4 Finar
10 Gangwal Chemicals
4 Ideal Cures Pvt Ltd
35 Kerry
3 Kima Chemical
6 Lonza Capsugel
15 Microlex e.U
2 Nanjing Bold Chemical
2 Nomisma Healthcare
2 Novo Excipients
1 Pharmatrans-Sanaq
4 Pluviaendo
1 Prachin Chemical
1 Qianhao Chemical (Hebei) Co., Ltd
1 Qualicaps
11 Roquette
17 Seppic
4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
1 Shanghai Welltone Material Technology Co., Ltd
1 Shijiazhuang Huaxu Pharmaceutical
3 Sigachi Industries
2 The Dow Chemical Company
2 Ulanqab Kema New Material
1 Valens Pharmachem
2 Vasa Pharmachem
1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

53 Fillers, Diluents & Binders, 47 Coating Systems & Additives, 43 Solubilizers, 39 Topical, 29 Parenteral, 26 Direct Compression, 24 Controlled & Modified Release, 21 Thickeners and Stabilizers, 21 Film Formers & Plasticizers, 19 Lubricants & Glidants, 18 Emulsifying Agents, 16 Granulation, 15 Co-Processed Excipients, 10 Surfactant & Foaming Agents, 9 Taste Masking, 6 Chewable & Orodispersible Aids, 6 API Stability Enhancers, 5 Empty Capsules, 4 Coloring Agents, 4 Vegetarian Capsules, 3 Disintegrants & Superdisintegrants, 2 Rheology Modifiers, 1 Soft Gelatin

DIGITAL CONTENT

6 NEWS #PharmaBuzz

media
6 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 5 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
5 Finished Drug Prices

MARKET PLACE

56 APIs, 4 FDF Dossiers

marketPlace
56 APIs
4 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 EDQM , 1 USP , 2 Others

otherSolutions
3 EDQM
1 USP
2 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 395

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

159

FDF Dossiers

114

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

722,064

Annual Reports (USD Million)

Finished Drug Prices

247 RELATED EXCIPIENT COMPANIES

421EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Neomycin sulfate, 1405-10-3, Neomycin trisulfate hydrate, Akos016010116

Molecular Formula

C₂₃H₄₈N₆O₁₇S

Molecular Weight

712.7 g/mol

InChI Key

OIXVKQDWLFHVGR-VTSVPHRWSA-N

Aminoglycoside antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C, and acts by inhibiting translation during protein synthesis.

1 2D Structure

Neomycin Sulfate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2R,3R,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4R,5R)-4-[(3R,4R,5R,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid

2.1.2 InChI

InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13+,14+,15-,16-,17-,18-,19+,20+,21-,22?,23+;/m1./s1

2.1.3 InChI Key

OIXVKQDWLFHVGR-VTSVPHRWSA-N

2.1.4 Canonical SMILES

C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O

2.1.5 Isomeric SMILES

C1[C@H]([C@@H]([C@@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@H]([C@H](O3)CO)OC4[C@@H]([C@H]([C@H]([C@@H](O4)CN)O)O)N)O)O)N.OS(=O)(=O)O

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Neomycin

2. Neomycin Palmitate

3. Neomycin Sulfate

2.2.2 Depositor-Supplied Synonyms

1. Neomycin Sulfate

2. 1405-10-3

3. Neomycin Trisulfate Hydrate

4. Akos016010116

2.3 Create Date

2013-05-31

3 Chemical and Physical Properties

Molecular Formula	C₂₃H₄₈N₆O₁₇S
Molecular Weight	712.7 g/mol
Hydrogen Bond Donor Count	15
Hydrogen Bond Acceptor Count	23
Rotatable Bond Count	9
Exact Mass	712.27966526 g/mol
Monoisotopic Mass	712.27966526 g/mol
Topological Polar Surface Area	436 Å²
Heavy Atom Count	47
Formal Charge	0
Complexity	953
Isotope Atom Count	0
Defined Atom Stereocenter Count	18
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Neomycin sulfate
Drug Label	Neomycin Sulfate Tablets, USP, for oral administration, contain neomycin which is an antibiotic obtained from the metabolic products of the actinomycete Streptomycesfradiae. Structurally, neomycin sulfate may be represented as follows:Chemically, i...
Active Ingredient	Neomycin sulfate
Dosage Form	Tablet
Route	Oral
Strength	500mg
Market Status	Prescription
Company	Oman Pharm Products; Teva; X Gen Pharms

2 of 2
Drug Name	Neomycin sulfate
Drug Label	Neomycin Sulfate Tablets, USP, for oral administration, contain neomycin which is an antibiotic obtained from the metabolic products of the actinomycete Streptomycesfradiae. Structurally, neomycin sulfate may be represented as follows:Chemically, i...
Active Ingredient	Neomycin sulfate
Dosage Form	Tablet
Route	Oral
Strength	500mg
Market Status	Prescription
Company	Oman Pharm Products; Teva; X Gen Pharms

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

Protein Synthesis Inhibitors

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Aminoglycosides [CS]; Aminoglycoside Antibacterial [EPC]

API SUPPLIERS

01

Sanofi

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Sanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

Contact Supplier

France

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

Portfolio PDF

Product Web Link

02

Rochem International Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3F18

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

03

Suanfarma

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #1B34

SuanFarma is present in all origins: Natural, Chemical & Biotechnological.

Contact Supplier

Spain

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

DKSH

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #6C42

DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

Contact Supplier

Switzerland

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

05

Pharm-RX Chemical

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

Corporate PDF

06

Pfizer CentreOne

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Contract Pharma 2024

Attending

Pfizer CentreOne is a global CDMO and a leading supplier of Specialty APIs.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF

CEP/COS

JDMF

EU-WC NDC KDMF VMF Others AUDIT

07

Yichang Sanxia Pharmaceutical Co.,...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

08

Merck & Co

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

09

Pfizer Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

10

Pfizer Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

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USDMF

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CEP/COS

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JDMF

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API Reference Price

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ROAD,"},{"dataSource":"API Import","activeIngredients":"NEOMYCIN SULFATE","year":"2021","qtr":"Q2","strtotime":1620930600,"product":"NEOMYCIN SULFATE (QTY: 4 X 200 MG, PRICE: USD-250\/EACH)(FOC)","address":"106, FIRST FLOOR , ASHOKA BHOOPALCHAMBERS BEGUMPET, S.P. 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NO 53, ALEAP INDUSTRIAL ESTATE, ,GAJULARAMARAM BEHIND PRAGATHINAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706985000,"product":"NEOMYCIN SULFATE USP MICRONIZED","address":"NO 31, RACE COURSE ROAD,BANGALORE","city":"BENGALURU,KARNATAKA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"CHICAGO O\\'HARE INT\\'L","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"734","totalValueFC":"3710.1","currency":"USD","unitRateINR":"61619.3","date":"04-Feb-2024","totalValueINR":"308096.5","totalValueInUsd":"3710.1","indian_port":"Madras Air","hs_no":"29419090","bill_no":"9968604","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"CHICAGO O\\'HARE INT\\'L","supplierAddress":"66 HUDSON BOULEVARD EASTNEW YORKNY 10001-2192 UNITED STATES","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706985000,"product":"NEOMYCIN SULFATE USP MICRONIZED","address":"NO 31, RACE COURSE ROAD,BANGALORE","city":"BENGALURU,KARNATAKA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"CHICAGO O\\'HARE INT\\'L","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"745","totalValueFC":"3765.7","currency":"USD","unitRateINR":"62542.8","date":"04-Feb-2024","totalValueINR":"312713.75","totalValueInUsd":"3765.7","indian_port":"Madras Air","hs_no":"29419090","bill_no":"9968604","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"CHICAGO O\\'HARE INT\\'L","supplierAddress":"66 HUDSON BOULEVARD EASTNEW YORKNY 10001-2192 UNITED STATES","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724265000,"product":"NEOMYCIN SULFATE, USP GRADE, LOW ENDOTOXIN (1405-10-3) (NOTFOR FOOD USE. TO BE USE ONLY AS AN EXCIPIENT IN PHARMACEUTIC","address":"140-D, POCKET-IV, PHASE-I","city":"NEW DELHI","supplier":"GLENTHAM LIFE SCIENCES ","supplierCountry":"UNITED KINGDOM","foreign_port":"LONDON - HEATHROW","customer":"MAAS PHARMA CHEMICALS","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"840","totalValueFC":"8850.4","currency":"USD","unitRateINR":"73495.8","date":"22-Aug-2024","totalValueINR":"734958.33","totalValueInUsd":"8850.4","indian_port":"Delhi Air","hs_no":"29419050","bill_no":"5194690","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"LONDON - HEATHROW","supplierAddress":"Unit 5 Leafield Way Corsham SN13 9SW United KingdomSDNF UNITED KINGDOM","customerAddress":"140-D, POCKET-IV, PHASE-I"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG ...DOSAGE - OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG BASE/GM;10,000 UNITS/GM

USFDA APPLICATION NUMBER - 50065

DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;E...DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM

USFDA APPLICATION NUMBER - 50168

DOSAGE - CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/G...DOSAGE - CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/GM;10,000 UNITS/GM

USFDA APPLICATION NUMBER - 50218

DOSAGE - SUSPENSION/DROPS;OTIC - EQ 3MG BASE/...DOSAGE - SUSPENSION/DROPS;OTIC - EQ 3MG BASE/ML;10MG/ML;EQ 3.3MG BASE/ML;0.5MG/ML

USFDA APPLICATION NUMBER - 50356

DOSAGE - OINTMENT;OPHTHALMIC - EQ 400 UNITS/G...DOSAGE - OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

USFDA APPLICATION NUMBER - 50417

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List of Suppliers' Co Processed Excipients Excipients Application used in Neomycin Sulfate on PharmaCompass.com

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ACTIVE PHARMA INGREDIENTS

23 API Suppliers

11 USDMF

5 CEP/COS

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1 KDMF

22 NDC API

10 VMF

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$ API Reference Price

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4 Europe

7 Canada

4 South Africa

30 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG BASE/GM;10,000 UNITS/GM

OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM

CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/GM;10,000 UNITS/GM

SUSPENSION/DROPS;OTIC - EQ 3MG BASE/ML;10MG/ML;EQ 3.3MG BASE/ML;0.5MG/ML

OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

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2 Vasa Pharmachem

1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

53 Fillers, Diluents & Binders

47 Coating Systems & Additives

43 Solubilizers

39 Topical

29 Parenteral

26 Direct Compression

24 Controlled & Modified Release