List of Related Excipient Companies and Suppliers of Imipramine Hydrochloride by Nanjing Bold Chemical on PharmaCompass.com

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ACTIVE PHARMA INGREDIENTS

20 API Suppliers, 13 USDMF, 1 CEP/COS, 2 JDMF, 3 EU WC, 1 KDMF, 7 NDC API, 7 Listed Suppliers, $ API Reference Price

20 API Suppliers
13 USDMF
1 CEP/COS
2 JDMF
3 EU WC
1 KDMF
7 NDC API
7 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

87 FDF Dossiers, 58 FDA Orange Book, 7 Canada, 4 South Africa, 18 Listed Dossiers

87 FDF Dossiers
58 FDA Orange Book
7 Canada
4 South Africa
18 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 10MG, TABLET;ORAL - 25MG, TABLET;ORAL - 50MG

drugProductComposition
TABLET;ORAL - 10MG
TABLET;ORAL - 25MG
TABLET;ORAL - 50MG

RELATED EXCIPIENT COMPANIES

4 SPI Pharma, 2 Seqens, 4 DKSH, 1 Jai Radhe Sales, 4 Boai NKY Pharmaceuticals Ltd, 12 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 1 ACG Worldwide, 6 Actylis, 1 Aeon Procare, 7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 21 BASF, 10 Corel Pharma Chem, 6 DFE Pharma, 1 Finar, 11 Gangwal Chemicals, 5 Ideal Cures Pvt Ltd, 3 Ingredion Pharma Solutions, 35 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 14 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nomisma Healthcare, 2 Novo Excipients, 3 Pharmatrans-Sanaq, 4 Pluviaendo, 3 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 19 Roquette, 13 Seppic, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 11 Sigachi Industries, 2 The Dow Chemical Company, 2 Ulanqab Kema New Material, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

72 Fillers, Diluents & Binders, 47 Coating Systems & Additives, 35 Direct Compression, 28 Controlled & Modified Release, 24 Thickeners and Stabilizers, 23 Solubilizers, 21 Disintegrants & Superdisintegrants, 20 Granulation, 18 Lubricants & Glidants, 18 Co-Processed Excipients, 13 Film Formers & Plasticizers, 11 Topical, 11 Parenteral, 8 Taste Masking, 7 Emulsifying Agents, 6 Chewable & Orodispersible Aids, 6 API Stability Enhancers, 5 Coloring Agents, 5 Empty Capsules, 4 Vegetarian Capsules, 3 Rheology Modifiers, 2 Surfactant & Foaming Agents

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 2 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
2 Finished Drug Prices

MARKET PLACE

2 APIs, 1 FDF Dossiers

marketPlace
2 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 EDQM , 1 USP , 3 JP , 1 Others

otherSolutions
3 EDQM
1 USP
3 JP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 211

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

5,368,661

Annual Reports (USD Million)

Finished Drug Prices

233 RELATED EXCIPIENT COMPANIES

387EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 113-52-0, Imipramine hcl, Tofranil, Pryleugan, Imizine, Chimoreptin

Molecular Formula

C₁₉H₂₅ClN₂

Molecular Weight

316.9 g/mol

InChI Key

XZZXIYZZBJDEEP-UHFFFAOYSA-N

FDA UNII

BKE5Q1J60U

The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.

1 2D Structure

Imipramine Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride

2.1.2 InChI

InChI=1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

2.1.3 InChI Key

XZZXIYZZBJDEEP-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

2.2 Other Identifiers

2.2.1 UNII

BKE5Q1J60U

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4,4'-methylenebis(3-hydroxy-2-naphthoic Acid)-3-(10,11-dihydro-5h-dibenzo(b,f)azepin-5-yl)-n,n-dimethyl-1-propanamine (1:2)

2. Imidobenzyle

3. Imipramine

4. Imipramine Monohydrochloride

5. Imipramine Pamoate

6. Imizin

7. Janimine

8. Melipramine

9. Norchlorimipramine

10. Pryleugan

11. Tofranil

2.3.2 Depositor-Supplied Synonyms

1. 113-52-0

2. Imipramine Hcl

3. Tofranil

4. Pryleugan

5. Imizine

6. Chimoreptin

7. Chrytemin

8. Presamine

9. Feinalmin

10. Imilanyle

11. Persamine

12. Pertofram

13. Teperine

14. Tofranile

15. Iprogen

16. Janimine

17. Pramine

18. Imp Hydrochloride

19. Ia-pram

20. Imizin

21. Co Cap Imipramine 25

22. Melipramine Hcl

23. Antideprin Hydrochloride

24. Imipramini Hydrochloridum

25. Imipramine Monohydrochloride

26. Imizinum

27. Imidol

28. Imipramine (hydrochloride)

29. G 22355

30. 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-n,n-dimethylpropan-1-amine;hydrochloride

31. Nsc-114900

32. N-(3-dimethylaminopropyl)iminodibenzyl Hydrochloride

33. Bke5q1j60u

34. Mls000028430

35. Chebi:5882

36. Deprinol

37. 3-(10,11-dihydro-5h-dibenzo[b,f]azepin-5-yl)-n,n-dimethylpropan-1-amine Hydrochloride

38. 5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepine Monohydrochloride

39. 5h-dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-n,n-dimethyl-, Monohydrochloride

40. Sk-pramine

41. Psicopramine

42. Thymopramin

43. Dynazina

44. Efuranol

45. Fujisawa

46. Imipramini

47. Odeoxil

48. Smr000058388

49. Tipramine

50. Venefon

51. Vionyl

52. Tofranil (tn)

53. 5h-dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-n,n-dimethyl-, Monohydrochloride

54. G-22355

55. Imipram

56. Sk-pramine Hydrochloride

57. Imipramine Hydrochloride [jan]

58. Melipramine Hydrochloride

59. Sr-01000003064

60. Cas-113-52-0

61. Einecs 204-030-7

62. Mfcd00012669

63. Unii-bke5q1j60u

64. Nsc 114900

65. Imipraminehcl

66. Sk-pramine Hcl

67. Prestwick_277

68. Imipramine Hydrochloride [usp:jan]

69. Nebumetone Impurity D

70. N-(gamma-dimethylaminopropyl)iminodibenzyl Hydrochloride

71. 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-n,n-dimethyl-propan-1-amine

72. Cpd000058388

73. Opera_id_319

74. N-(gamma-dimetilaminopropil)-iminodibenzile Cloridrato [italian]

75. Surecn41766

76. Imipramine Hydrochloride Rs

77. 5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz(b,f)azepine Hydrochloride

78. 5h-dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)propyl)-, Hydrochloride

79. Chembl1692

80. Dsstox_cid_20738

81. Dsstox_rid_79581

82. Dsstox_gsid_40738

83. G 22150

84. Regid_for_cid_8228

85. Schembl41765

86. Mls001146891

87. Mls002222195

88. Spectrum1500348

89. N-(gamma-dimetilaminopropil)-iminodibenzile Cloridrato

90. Dtxsid7040738

91. Imipramine For System Suitability

92. Hms1568o05

93. Hms1920f17

94. Pharmakon1600-01500348

95. Hy-b1490

96. Tox21_301417

97. Tox21_500702

98. Ccg-40208

99. Imipramine Hydrochloride [mi]

100. Nsc114900

101. Nsc757074

102. S4377

103. Imipramine Hydrochloride (jp17/usp)

104. Akos015895330

105. Ac-7587

106. Cs-6180

107. Ks-1072

108. Lp00702

109. Nc00570

110. Nsc-757074

111. 5h-dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-, Monohydrochloride

112. Imipramine Hydrochloride [mart.]

113. Imipramine Hydrochloride [vandf]

114. Imipramine Hydrochloride [usp-rs]

115. Imipramine Hydrochloride [who-dd]

116. Imipramine Hydrochloride [who-ip]

117. Ncgc00024253-05

118. Ncgc00094054-01

119. Ncgc00094054-02

120. Ncgc00094054-03

121. Ncgc00094054-04

122. Ncgc00094054-05

123. Ncgc00255651-01

124. Ncgc00261387-01

125. (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine Hydrochloride

126. Bi164574

127. Imipramine Hydrochloride, >=99% (tlc)

128. Db-041172

129. Eu-0100702

130. Ft-0631652

131. Ft-0670318

132. I0971

133. St50985122

134. Sw196582-4

135. Imipramine Hydrochloride [orange Book]

136. C07982

137. D00815

138. I 7379

139. Imipramine Hydrochloride [ep Monograph]

140. Imipramine Hydrochloride [usp Impurity]

141. Imipramine Hydrochloride [usp Monograph]

142. Imipramini Hydrochloridum [who-ip Latin]

143. 113i520

144. Imipramine Hydrochloride, Bioxtra, >=99% (tlc)

145. Imipramine Hydrochloride, Sigma Reference Standard

146. J-002975

147. Lmipramine Hydrochloride 100 Microg/ml In Methanol

148. Q-200878

149. Sr-01000003064-2

150. Sr-01000003064-7

151. 5-(3-dimethylaminopropyl)-10,f)azepine Hydrochloride

152. Q27106923

153. Wln: T C676 Bn & T & J B3n1 & 1 & Gh

154. Z1551429721

155. N-(.gamma.-dimethylaminopropyl)iminodibenzyl Hydrochloride

156. 5h-dibenz[b, 10,11-dihydro-n,n-dimethyl-, Monohydrochloride

157. Imipramine Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

158. 5h-dibenz[b, 10,11-dihydro-5-[3-(dimethylamino)propyl]-, Hydrochloride

159. Imipramine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

160. 10,11-dihydro-n,n-dimethyl-5h-dibenzo[b,f]azepine-5-propanamine Hydrochloride

161. 5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz-[b,f]-azepine, Hydrochloride

162. 5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenzo[b,f]azepine Hydrochloride

163. 5h-dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-n,n-dimethyl-, Hydrochloride (1:1)

164. 5h-dibenz[b, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, Monohydrochloride

165. Imipramine For System Suitability, European Pharmacopoeia (ep) Reference Standard

166. Imipramine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

167. Imipramine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

168. (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine Hydrochloride

169. Imipramine Hydrochloride Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₂₅ClN₂
Molecular Weight	316.9 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	316.1706265 g/mol
Monoisotopic Mass	316.1706265 g/mol
Topological Polar Surface Area	6.5 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	291
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Imipramine hydrochloride
PubMed Health	Imipramine (By mouth)
Drug Classes	Antidepressant, Urinary Enuresis Agent
Drug Label	Imipramine hydrochloride, the original tricyclic antidepressant, is a member of the dibenzazepine group of compounds. It is designated 5-[3-(Dimethylamino) propyl]-10, 11-dihydro-5H-dibenz [b,f]-azepine monohydrochloride. Structurally, it may be repr...
Active Ingredient	Imipramine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 50mg; 10mg
Market Status	Prescription
Company	Excellium; Lupin; Sandoz; Par Pharm; Mutual Pharm

2 of 4
Drug Name	Tofranil
Drug Label	Tofranil is supplied in tablet form for oral administration.Tofranil, imipramine hydrochloride USP, the original tricyclic antidepressant, is a member of the dibenzazepine group of compounds. It is designated 5-3-(dimethylamino)propyl-10,11-dihydr...
Active Ingredient	Imipramine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 50mg; 10mg
Market Status	Prescription
Company	Mallinckrodt

3 of 4
Drug Name	Imipramine hydrochloride
PubMed Health	Imipramine (By mouth)
Drug Classes	Antidepressant, Urinary Enuresis Agent
Drug Label	Imipramine hydrochloride, the original tricyclic antidepressant, is a member of the dibenzazepine group of compounds. It is designated 5-[3-(Dimethylamino) propyl]-10, 11-dihydro-5H-dibenz [b,f]-azepine monohydrochloride. Structurally, it may be repr...
Active Ingredient	Imipramine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 50mg; 10mg
Market Status	Prescription
Company	Excellium; Lupin; Sandoz; Par Pharm; Mutual Pharm

4 of 4
Drug Name	Tofranil
Drug Label	Tofranil is supplied in tablet form for oral administration.Tofranil, imipramine hydrochloride USP, the original tricyclic antidepressant, is a member of the dibenzazepine group of compounds. It is designated 5-3-(dimethylamino)propyl-10,11-dihydr...
Active Ingredient	Imipramine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 50mg; 10mg
Market Status	Prescription
Company	Mallinckrodt

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Adrenergic Uptake Inhibitors

Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (See all compounds classified as Adrenergic Uptake Inhibitors.)

Antidepressive Agents, Tricyclic

Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. (See all compounds classified as Antidepressive Agents, Tricyclic.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Tricyclic Antidepressant [EPC]

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USDMF

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KDMF

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API Reference Price

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OF","customerCountry":"PAKISTAN","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"67","totalValueFC":"6704.6","currency":"USD","unitRateINR":5567.6999999999998,"date":"29-Aug-2024","totalValueINR":"556770","totalValueInUsd":"6704.6","indian_port":"Bangalore ICD","hs_no":"29420024","bill_no":"3594475","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore ICD","supplierAddress":"RAY HOUSE, HIG 2000,,MOTHER DIARY, BANGALORE,KARNATAKA","customerAddress":""}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - TABLET;ORAL - 10MG

USFDA APPLICATION NUMBER - 87846

DOSAGE - TABLET;ORAL - 25MG

USFDA APPLICATION NUMBER - 87846

DOSAGE - TABLET;ORAL - 50MG

USFDA APPLICATION NUMBER - 87846

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List of Related Excipient Companies and Suppliers of Imipramine Hydrochloride by Nanjing Bold Chemical on PharmaCompass.com

Imipramine Hydrochloride

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

20 API Suppliers

13 USDMF

1 CEP/COS

2 JDMF

3 EU WC

1 KDMF

7 NDC API

7 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

87 FDF Dossiers

58 FDA Orange Book

7 Canada

4 South Africa

18 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 10MG

TABLET;ORAL - 25MG

TABLET;ORAL - 50MG

RELATED EXCIPIENT COMPANIES

4 SPI Pharma

2 Seqens

4 DKSH

1 Jai Radhe Sales

4 Boai NKY Pharmaceuticals Ltd

12 Gangwal Healthcare

2 Nanjing Well Pharmaceutical

1 Pfanstiehl

1 ACG Worldwide

6 Actylis

1 Aeon Procare

7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

21 BASF

10 Corel Pharma Chem

6 DFE Pharma

1 Finar

11 Gangwal Chemicals

5 Ideal Cures Pvt Ltd

3 Ingredion Pharma Solutions

35 Kerry

3 Kima Chemical

6 Lonza Capsugel

14 Microlex e.U

1 Nanjing Bold Chemical

2 Nomisma Healthcare

2 Novo Excipients

3 Pharmatrans-Sanaq

4 Pluviaendo

3 Prachin Chemical

1 Qianhao Chemical (Hebei) Co., Ltd

1 Qualicaps

19 Roquette

13 Seppic

5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Shanghai Welltone Material Technology Co., Ltd

11 Sigachi Industries

2 The Dow Chemical Company

2 Ulanqab Kema New Material

3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

72 Fillers, Diluents & Binders

47 Coating Systems & Additives

35 Direct Compression

28 Controlled & Modified Release

24 Thickeners and Stabilizers

23 Solubilizers

21 Disintegrants & Superdisintegrants

20 Granulation

18 Lubricants & Glidants

18 Co-Processed Excipients

13 Film Formers & Plasticizers

11 Topical

11 Parenteral