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Also known as: 107-51-7, Trisiloxane, octamethyl-, Poly(dimethylsiloxane), 1,1,1,3,3,5,5,5-octamethyltrisiloxane, Dimeticone, Dimethyl-bis(trimethylsilyloxy)silane
Molecular Formula
C8H24O2Si3
Molecular Weight
236.53  g/mol
InChI Key
CXQXSVUQTKDNFP-UHFFFAOYSA-N
FDA UNII
9G1ZW13R0G

Dimethicone
1 2D Structure

Dimethicone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
dimethyl-bis(trimethylsilyloxy)silane
2.1.2 InChI
InChI=1S/C8H24O2Si3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h1-8H3
2.1.3 InChI Key
CXQXSVUQTKDNFP-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C
2.2 Other Identifiers
2.2.1 UNII
9G1ZW13R0G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Baysilon

2. Macroplastique

3. Poly(dimethylsiloxane)

4. Polydimethylsiloxane

5. Rtv S-5392

6. Silastic

7. Siliconique

8. Silikon 1000

9. Simpa

2.3.2 Depositor-Supplied Synonyms

1. 107-51-7

2. Trisiloxane, Octamethyl-

3. Poly(dimethylsiloxane)

4. 1,1,1,3,3,5,5,5-octamethyltrisiloxane

5. Dimeticone

6. Dimethyl-bis(trimethylsilyloxy)silane

7. Dimethicone 350

8. 63148-62-9

9. Pentamethyl(trimethylsilyloxy)disiloxane

10. Dimethylbis(trimethylsiloxy)silane

11. 9g1zw13r0g

12. Chebi:9147

13. Trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-

14. Dimethylbis(trimethylsilyloxy)silane

15. Dimethicones

16. Poly(dimethylsiloxane), Hydroxy Terminated

17. Mfcd00084411

18. Mfcd00134211

19. Mfcd00148360

20. Ccris 3198

21. Poly(dimethylsiloxane), Trimethylsiloxy Terminated

22. Einecs 203-497-4

23. Dimeticonum

24. Unii-9g1zw13r0g

25. Dimeticona

26. Frd 20

27. Ctamethyltrisiloxane

28. Mfcd00008264

29. Pentamethyl(trimethylsiloxy)disiloxane

30. Octamethyl-trisiloxane

31. Pdms

32. Dimethicone Macromolecule

33. Volasil Dm-1

34. Silicon Oil For Oil Bath

35. Trisiloxane [inci]

36. Dm-fluid 1.0cs

37. Ec 203-497-4

38. Octamethyltrisiloxane, 98%

39. Dsstox_cid_20710

40. Dsstox_rid_79558

41. Dsstox_gsid_40710

42. Os 20 (siloxane)

43. Schembl23459

44. Siliconoil Pharma 100 Cst.

45. Dimethyl Polysiloxane, Bis(trimethylsilyl)-terminated

46. Dow Corning High-vacuum Grease

47. Chembl2142985

48. Dtxsid9040710

49. Chebi:31498

50. Cxqxsvuqtkdnfp-uhfffaoysa-

51. Kf 96a1

52. Octamethyltrisiloxane [mi]

53. Dimethylbis(trimethylsiloxy)siliane

54. Polydimethylsiloxane, 1000 Cst.

55. Alpha-(trimethylsilyl)-omega-methylpoly(oxy(dimethylsilylene))

56. [(ch3)3sio]2si(ch3)2

57. Tox21_301002

58. Co9816

59. Mfcd00165850

60. Silane, Dimethylbis(trimethylsiloxy)-

61. Akos015840180

62. Zinc169747808

63. Antifoam Compound For Anhydrous Systems

64. Fs-4459

65. Ncgc00164100-01

66. Ncgc00164100-02

67. Ncgc00254904-01

68. Cas-107-51-7

69. Db-040764

70. Ft-0631598

71. Ft-0696355

72. O0257

73. O9816

74. C07261

75. D91850

76. S12475

77. A801717

78. Xiameter(r) Pmx-200 Silicone Fluid 1 Cst

79. J-001906

80. Poly(dimethylsiloxane), Viscosity 1.0 Cst (25 C)

81. Q2013799

82. Xiameter(r) Pmx-200 Silicone Fluid 20 Cs

83. 2,2,4,4,6,6-hexamethyl-3,5-dioxa-2,4,6-trisilaheptane

84. Polydimethylsiloxane, 20,000 Cst. Trimethoxysilyl Terminated

85. Polydimethylsiloxane, Extreme Low Volatility, Viscosity 1000 Cst.

86. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 20% Active, Viscosity 1500cst

87. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 30% Active, Viscosity 1500cst

88. Polydimethylsiloxane, Trimethylsiloxy Terminated, Reduced Volatility, Viscosity 20 Cst.

89. 28349-86-2

90. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 10% Active, Viscosity 1000-2000cst

91. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 10% Active, Viscosity 800-2000cst

92. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 20% Active, Viscosity 1000-2000cst

93. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 30% Active, Viscosity 1000-2000cst

94. Polydimethylsiloxane, Trimethylsiloxy Terminated, Extreme Low Volatility, Viscosity 12.500 Cst.

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 236.53 g/mol
Molecular Formula C8H24O2Si3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass236.10840961 g/mol
Monoisotopic Mass236.10840961 g/mol
Topological Polar Surface Area18.5 Ų
Heavy Atom Count13
Formal Charge0
Complexity149
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 FDA Pharmacological Classification
4.1.1 Pharmacological Classes
Skin Barrier Activity [PE]
4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents

P03A - Ectoparasiticides, incl. scabicides

P03AX - Other ectoparasiticides, incl. scabicides

P03AX05 - Dimeticone


API Reference Price

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OF","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"101, SAI SIDDHI BLDG, PLOT, NAVI MUMBAI, M.S.","customerAddress":""},{"dataSource":"API Import","activeIngredients":"DIMETHICONE","year":"2021","qtr":"Q1","strtotime":1616178600,"product":"ARLASILK EFA-LQ-(AP) (LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDEPHOSPHATE DIMETHICONE AND AQUA)","address":"6, FORT VIJAY SOC.,1\/3, GOLA LANE,DR. D. N. ROAD, FORT,","city":"MUMBAI. MAHARASHTRA.","supplier":"CRODA INTERNATIONAL PLC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. 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ROAD, FORT,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1641580200,"product":"ARLASILK PLN-LQ-(AP) (LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDEPHOSPHATE DIMETHICONE AND AQUA)","address":"PLOT NO 1\/1 PART TTC INDL AREA THANE-BELAPUR ROAD KOPARKHAIRNE Con","city":"NAVI MUMBAI MAHARASHTRA","supplier":"CRODA INTERNATIONAL PLC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"CRODA INTERNATIONAL PLC","customerCountry":"INDIA","quantity":"54.00","actualQuantity":"54","unit":"KGS","unitRateFc":"35.5","totalValueFC":"1989.6","currency":"USD","unitRateINR":"2744.7","date":"08-Jan-2022","totalValueINR":"148212.4","totalValueInUsd":"1989.6","indian_port":"BOMBAY AIR","hs_no":"29232090","bill_no":"7003880","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"","customerAddress":"PLOT NO 1\/1 PART TTC INDL AREA THANE-BELAPUR ROAD KOPARKHAIRNE Con"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655577000,"product":"11367 BRB SG 126 (CYCLOPENTASILOXANE, DIMETHICONE\/VINYL DIMETHICONE CROSSPOLYMER) (RAW MATERIAL FOR COSMATICS USE)","address":"M 10 SOUTH EXTENSION PART II,","city":"NEW DELHI,DELHI","supplier":"CETES COSMETICS AG","supplierCountry":"POLAND","foreign_port":"NA","customer":"ORIFLAME INDIA PRIVATE ","customerCountry":"INDIA","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"2410.7","totalValueFC":"659.2","currency":"INR","unitRateINR":"2571.3","date":"19-Jun-2022","totalValueINR":"51425.24","totalValueInUsd":"659.2","indian_port":"DELHI TKD ICD","hs_no":"29054900","bill_no":"9185810","productDescription":"API","marketType":"REGULATED MARKET","country":"POLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"M 10 SOUTH EXTENSION PART II,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1678732200,"product":"ARLASILK PLN-LQ-(AP) (LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDEPHOSPHATE DIMETHICONE AND AQUA)","address":"PLOT NO 1\/1 PART TTC INDL AREA THANE-BELAPUR ROAD KOPARKHAIRNE Con","city":"NAVI MUMBAI MAHARASHTRA","supplier":"CRODA INTERNATIONAL PLC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"CRODA INTERNATIONAL PLC","customerCountry":"INDIA","quantity":"36.00","actualQuantity":"36","unit":"KGS","unitRateFc":"38.8","totalValueFC":"1799.1","currency":"USD","unitRateINR":"4110.5","date":"14-Mar-2023","totalValueINR":"147976.56","totalValueInUsd":"1799.1","indian_port":"BOMBAY AIR","hs_no":"29232090","bill_no":"5041467","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO 1\/1 PART TTC INDL AREA THANE-BELAPUR ROAD KOPARKHAIRNE Con"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699209000,"product":"ARLASILK PLN-LQ-(AP) (WATER (AND) LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE DIMETHICONE)","address":"PLOT NO 1\/1 PART TTC INDL AREA","city":"NAVI MUMBAI. MAHARASHTRA.","supplier":"CRODA INTERNATIONAL PLC","supplierCountry":"UNITED STATES","foreign_port":"N\/A","customer":"CRODA INTERNATIONAL PLC","customerCountry":"INDIA","quantity":"36.00","actualQuantity":"36","unit":"KGS","unitRateFc":"45.8","totalValueFC":"1880.7","currency":"USD","unitRateINR":"4338.4","date":"06-Nov-2023","totalValueINR":"156181.09","totalValueInUsd":"1880.7","indian_port":"Bombay Air","hs_no":"29232090","bill_no":"8637277","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"PLOT NO 1\/1 PART TTC INDL AREA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709231400,"product":"ARLASILK PLN-LQ-(AP) (LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDEPHOSPHATE DIMETHICONE AND AQUA)","address":"PLOT NO 1\/1 PART TTC INDL AREA","city":"NAVI MUMBAI. MAHARASHTRA.","supplier":"CRODA INTERNATIONAL PLC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"CRODA INTERNATIONAL PLC","customerCountry":"INDIA","quantity":"36.00","actualQuantity":"36","unit":"KGS","unitRateFc":"48.9","totalValueFC":"2097","currency":"USD","unitRateINR":"4837.3","date":"01-Mar-2024","totalValueINR":"174142.16","totalValueInUsd":"2097","indian_port":"Bombay Air","hs_no":"29232090","bill_no":"2377104","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"777 SCUDDERS MILL ROAD, BLDG. 2 SUITE 200 PLAINSBORO, NJ 08536 New JERSEY, , UNITED STATES UNITED STATES","customerAddress":"PLOT NO 1\/1 PART TTC INDL AREA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718649000,"product":"ARLASILK PLN-LQ-(AP) (WATER (AND)LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE DIMETHICONE)","address":"PLOT NO 1\/1 PART TTC INDL AREA","city":"NAVI MUMBAI. MAHARASHTRA.","supplier":"CRODA INTERNATIONAL PLC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. 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20-Mar-2021
18-Jun-2024
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