List of Suppliers' Film Formers Plasticizers Excipients Application used in Prestwick2_000955 on PharmaCompass.com

Prestwick2_000955

Suanfarma Florfenicol

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FAMAR CDMO- From early development to commercial manufacturing.

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Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

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Veranova: A CDMO that manages complexity with confidence.

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ACTIVE PHARMA INGREDIENTS

12 API Suppliers, 1 EU WC, 2 NDC API, 11 VMF, 11 Listed Suppliers

12 API Suppliers
1 EU WC
2 NDC API
11 VMF
11 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers, 9 Canada, 10 Listed Dossiers

19 FDF Dossiers
9 Canada
10 Listed Dossiers

RELATED EXCIPIENT COMPANIES

2 Boai NKY Pharmaceuticals Ltd, 5 Gangwal Healthcare, 3 Nanjing Well Pharmaceutical, 1 ACG Worldwide, 2 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 11 BASF, 10 Corel Pharma Chem, 2 DFE Pharma, 4 Gangwal Chemicals, 4 Ideal Cures Pvt Ltd, 26 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 4 Microlex e.U, 2 Novo Excipients, 1 Pharmatrans-Sanaq, 2 Pluviaendo, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 6 Seppic, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 2 Sigachi Industries, 2 The Dow Chemical Company, 1 Ulanqab Kema New Material

EXCIPIENTS BY APPLICATIONS

39 Coating Systems & Additives, 31 Fillers, Diluents & Binders, 21 Controlled & Modified Release, 14 Direct Compression, 12 Solubilizers, 11 Granulation, 7 Film Formers & Plasticizers, 7 Parenteral, 6 Co-Processed Excipients, 5 Empty Capsules, 4 Vegetarian Capsules, 3 Disintegrants & Superdisintegrants, 3 API Stability Enhancers, 3 Topical, 2 Taste Masking, 2 Coloring Agents, 2 Emulsifying Agents, 2 Thickeners and Stabilizers, 1 Rheology Modifiers, 1 Chewable & Orodispersible Aids

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12 APIs

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12 APIs

Suanfarma Florfenicol

Synopsis

ACTIVE PHARMA INGREDIENTS

12

API Suppliers

0

USDMF

0

CEP/COS

CEP/COS Certifications

0

JDMF

1

EU WC

0

KDMF

2

NDC API

11

VMF

11

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 0

MARKET PLACE

12

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

19

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

9

Canada

0

Australia

0

South Africa

10

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

3

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

NA

Annual Reports (USD Million)

NA

Finished Drug Prices

NA

103 RELATED EXCIPIENT COMPANIES

176EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 73231-34-2, Nuflor, (-)-florfenicol, Sch-25298, 76639-94-6, Sch 25298

Molecular Formula

C₁₂H₁₄Cl₂FNO₄S

Molecular Weight

358.2 g/mol

InChI Key

AYIRNRDRBQJXIF-NXEZZACHSA-N

FDA UNII

9J97307Y1H

Florfenicol

Florfenicol is a fluorinated synthetic analog of thiamphenicol.

1 2D Structure

Florfenicol

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

2.1.2 InChI

InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

2.1.3 InChI Key

AYIRNRDRBQJXIF-NXEZZACHSA-N

2.1.4 Canonical SMILES

CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)NC(=O)C(Cl)Cl)O

2.1.5 Isomeric SMILES

CS(=O)(=O)C1=CC=C(C=C1)[C@H]([C@@H](CF)NC(=O)C(Cl)Cl)O

2.2 Other Identifiers

2.2.1 UNII

9J97307Y1H

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 3-fluorothiamphenicol

2. Chloramphen

3. Florphenicol

4. Sch 25298

5. Sch-25298

6. Thiamphenicol, 3-fluoro

2.3.2 Depositor-Supplied Synonyms

1. 73231-34-2

2. Nuflor

3. (-)-florfenicol

4. Sch-25298

5. 76639-94-6

6. Sch 25298

7. Nuflor Gold

8. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

9. Chebi:87185

10. D-threo-2,2-dichloro-n-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

11. 9j97307y1h

12. Nsc-759287

13. Acetamide, 2,2-dichloro-n-((1s,2r)-1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-

14. Aquafen

15. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide

16. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide

17. Dsstox_cid_25500

18. Dsstox_rid_80918

19. Dsstox_gsid_45500

20. Acetamide, 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-, (r-(r*,s*))-

21. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl]acetamide

22. D-(-)-threo-2-dichloroacetamido-3-fluoro-1-(4-methylsulfonylphenyl)-1-propanol

23. Florfenicol [usan:inn:ban]

24. 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide

25. Unii-9j97307y1h

26. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl)acetamide

27. Ncgc00016922-01

28. Cas-73231-34-2

29. Mfcd00864834

30. Nuflor (tn)

31. Florfenicol [mi]

32. Prestwick0_000955

33. Prestwick1_000955

34. Prestwick2_000955

35. Prestwick3_000955

36. Florfenicol [inn]

37. Florfenicol [jan]

38. Florfenicol (usan/inn)

39. Florfenicol [usan]

40. Florfenicol [mart.]

41. Schembl49425

42. Bspbio_000950

43. Mls002154071

44. Spbio_003099

45. Bpbio1_001046

46. Chembl1241590

47. Dtxsid9045500

48. Florfenicol [green Book]

49. Schembl21835523

50. (-)-florfenicol;sch-25298

51. Hms1570p12

52. Hms2090i10

53. Hms2097p12

54. Hms2230k18

55. Hms3714p12

56. Zinc537733

57. Act06682

58. Hy-b1374

59. Osurnia Component Florfenicol

60. Zeleris Component Florfenicol

61. Tox21_110683

62. S4201

63. Akos015889457

64. Tox21_110683_1

65. Ac-4340

66. Ccg-220955

67. Cs-4857

68. Db11413

69. Florfenicol Component Of Osurnia

70. Florfenicol Component Of Zeleris

71. Ks-5028

72. Nsc 759287

73. 2,2-dichloro-n-[(1s,2r)-1-(fluoromethyl)-2-hydroxy-2-(4-methylsulfonylphenyl)ethyl]acetamide

74. Florfenicol [ema Epar Veterinary]

75. Ncgc00179366-01

76. Ncgc00179366-03

77. Ncgc00179366-04

78. 2,2-dichloro-n-((alphas,betar)-alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

79. Benzenesulfonic Acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, Methyl Ester, (r-(r*,s*))-

80. Bf166386

81. Smr001233384

82. (methylsulfonyl)phenyl)propan-2-yl)acetamide

83. Ab00513976

84. F0811

85. Sw197224-3

86. D04194

87. T72886

88. Ab00513976_09

89. 231f342

90. A838774

91. Q408400

92. Florfenicol, Analytical Standard, For Drug Analysis

93. Brd-k11298197-001-03-9

94. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-

95. (1r,2s)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl) Phenyl]-1-propanol

96. (1r,2s)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl)phenyl]-1-propanol

97. 2,2-dichlor-n-((1r,2s)-3-fluor-1-hydroxy- 1-(4-(methylsulfonyl)-phenyl)-propan-2-yl)-ethanamide

98. 2,2-dichloro-n-((.alpha.s,.beta.r)-.alpha.-(fluoromethyl)-.beta.-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

99. 2,2-dichloro-n-[(1r,2r)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

100. 2,2-dichloro-n-{(1r,2s)-3-fluoro-1-hydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide

101. D-threo-2,2-dichloro-n-(.alpha.-(fluoromethyl)-.beta.-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₄Cl₂FNO₄S
Molecular Weight	358.2 g/mol
XLogP3	0.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	357.0004627 g/mol
Monoisotopic Mass	357.0004627 g/mol
Topological Polar Surface Area	91.8 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	447
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

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Coating Systems & Additives

Fillers, Diluents & Binders

Controlled & Modified Release

Direct Compression

Solubilizers

Granulation

Film Formers & Plasticizers

Parenteral

Co-Processed Excipients

Empty Capsules

Vegetarian Capsules

Disintegrants & Superdisintegrants

API Stability Enhancers

Topical

Taste Masking

Coloring Agents

Emulsifying Agents

Thickeners and Stabilizers

Rheology Modifiers

Chewable & Orodispersible Aids

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