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Chemistry

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Also known as: 62-31-7, 3-hydroxytyramine hydrochloride, Dopamine hcl, Intropin, 4-(2-aminoethyl)benzene-1,2-diol hydrochloride, Cardiosteril
Molecular Formula
C8H12ClNO2
Molecular Weight
189.64  g/mol
InChI Key
CTENFNNZBMHDDG-UHFFFAOYSA-N
FDA UNII
7L3E358N9L

Dopamine
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
1 2D Structure

Dopamine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-(2-aminoethyl)benzene-1,2-diol;hydrochloride
2.1.2 InChI
InChI=1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
2.1.3 InChI Key
CTENFNNZBMHDDG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC(=C(C=C1CCN)O)O.Cl
2.2 Other Identifiers
2.2.1 UNII
7L3E358N9L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3,4 Dihydroxyphenethylamine

2. 3,4-dihydroxyphenethylamine

3. 4-(2-aminoethyl)-1,2-benzenediol

4. Dopamine

5. Hydrochloride, Dopamine

6. Hydroxytyramine

7. Intropin

2.3.2 Depositor-Supplied Synonyms

1. 62-31-7

2. 3-hydroxytyramine Hydrochloride

3. Dopamine Hcl

4. Intropin

5. 4-(2-aminoethyl)benzene-1,2-diol Hydrochloride

6. Cardiosteril

7. Dopastat

8. Revivan

9. Inotropin

10. Tensamin

11. Dopamine.hcl

12. 3,4-dihydroxyphenethylamine Hydrochloride

13. Dynatra

14. 1,2-benzenediol, 4-(2-aminoethyl)-, Hydrochloride

15. 4-(2-aminoethyl)pyrocatechol Hydrochloride

16. (dopamine Hcl)

17. 2-(3,4-dihydroxyphenyl)ethylamine Hydrochloride

18. M-hydroxytyramine Hydrochloride

19. Dopamine (hydrochloride)

20. 3-hydroxytyramine, Hydrochloride

21. Asl-279

22. P 498

23. 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride

24. Nsc-169105

25. Mls000069419

26. 7l3e358n9l

27. Smr000059081

28. Dopamine Chloride

29. Dopamine Fresenius

30. 62-31-7 (hcl); 51-61-6 (free Base)

31. 1200398-97-5

32. 1,2-benzenediol, 4-(2-aminoethyl)-, Hydrochloride (1:1)

33. 3-hydroxytyraminium Chloride

34. Abbodop

35. Rascordin

36. Pyrocatechol, 4-(2-aminoethyl)-, Hydrochloride

37. 1,2-benzenediol, 4-(2-aminoethyl)-, Hydrochloride (1:1), Homopolymer

38. Nsc169105

39. Einecs 200-527-8

40. Nsc 169105

41. Unii-7l3e358n9l

42. Sr-01000075366

43. .beta.-(3,4-dihydroxyphenyl)ethylamine Hydrochloride

44. Actopamin (tn)

45. Dopamine Hcl Salt

46. Intropin (tn)

47. Beta-(3,4-dihydroxyphenyl)ethylamine Hydrochloride

48. Dopamine Hydrochloride In Dextrose 5%

49. Dopamine Hydrochloride And Dextrose 5%

50. Dopamini Hydrochloridum

51. 3-hydroxytyramine Hcl

52. Dopamine Hydrochloride [usan:usp:jan]

53. 3-hydroxytyramine, Hcl

54. Opera_id_218

55. 3,4-dihydroxyphenyl-ethylamine Hydrochloride

56. Dopamine Hydrogen Chloride

57. Dsstox_cid_550

58. Intropin [as Hydrochloride]

59. Dopamini Hydrochloridum,(s)

60. Chembl1557

61. Dsstox_rid_75655

62. Dsstox_gsid_20550

63. Schembl40951

64. 335081-04-4

65. Mls001074180

66. Spectrum1500263

67. Asl279

68. Chebi:4698

69. Sgcut00110

70. Dtxsid7020550

71. Hy-b0451a

72. Dopamine Hydrochloride And Dextrose 5% In Plastic Container

73. Dopamine Hydrochloride In Dextrose 5% In Plastic Container

74. Dopamine Hydrochloride (inotropin)

75. Hms1920i18

76. Kuc104380c

77. Pharmakon1600-01500263

78. Dopamine Hydrochloride [mi]

79. Bcp06611

80. To_000060

81. Dopamine Hydrochloride (jp17/usp)

82. Dopamine Hydrochloride [jan]

83. Tox21_201018

84. Tox21_500586

85. Ccg-40211

86. Dopamine Hydrochloride [usan]

87. Nsc756749

88. S2529

89. Dopamine Hydrochloride [vandf]

90. Akos008056421

91. Dopamine Hydrochloride [mart.]

92. 1, 4-(2-aminoethyl)-, Hydrochloride

93. Dopamine Hydrochloride [usp-rs]

94. Dopamine Hydrochloride [who-dd]

95. Dopamine Hydrochloride [who-ip]

96. Ks-5304

97. Ksc-10-159

98. Lp00586

99. Nc00545

100. Nsc-756749

101. 3,4-dihydoxyphenethylamine Hydrochloride

102. Cas-62-31-7

103. Ncgc00093965-01

104. Ncgc00093965-02

105. Ncgc00093965-03

106. Ncgc00093965-04

107. Ncgc00258571-01

108. Ncgc00261271-01

109. 3,4-dihydroxyphenylethylaminehydrochloride

110. Ac-12190

111. Bd166234

112. Db-023081

113. Dopamine Hydrochloride [orange Book]

114. A0305

115. Am20080715

116. Dopamine Hydrochloride [ep Monograph]

117. Eu-0100586

118. Ft-0603260

119. Ft-0667775

120. Ft-0695562

121. Sw199608-2

122. Dopamine Hydrochloride [usp Monograph]

123. Dopamini Hydrochloridum [who-ip Latin]

124. D00633

125. F10519

126. H 8502

127. 2-(3,4-dihydroxyphenyl)ethyl-1-13c-amine Hcl

128. 2-(3,4-dihydroxyphenyl)-ethylamine Hydrochloride

129. A937196

130. Dopamine Hydrochloride, Puriss., >=98.5% (at)

131. Sr-01000075366-1

132. Sr-01000075366-8

133. Q27268491

134. F0001-1648

135. Z262221794

136. 963ad780-3e96-47b5-9044-7e59f6c84d67

137. Dopamine Hydrochloride, Certified Reference Material, Tracecert(r)

138. Dopamine Hydrochloride, British Pharmacopoeia (bp) Reference Standard

139. Dopamine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

140. Dopamine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

141. Dopamine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

142. Dopamine Hydrochloride Solution, 1.0 Mg/ml In Methanol With 5% 1 M Hcl (as Free Base), Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 189.64 g/mol
Molecular Formula C8H12ClNO2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass189.0556563 g/mol
Monoisotopic Mass189.0556563 g/mol
Topological Polar Surface Area66.5 Ų
Heavy Atom Count12
Formal Charge0
Complexity119
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameDopamine hydrochloride
Drug LabelDopamine Hydrochloride in 5% Dextrose Injection, USP is a sterile, nonpyrogenic, prediluted solution of dopamine hydrochloride in 5% dextrose injection. It is administered by intravenous infusion.Each 100 mL contains dopamine hydrochloride 80 mg (0.8...
Active IngredientDopamine hydrochloride
Dosage FormInjectable
RouteInjection
Strength80mg/ml; 160mg/100ml; 40mg/ml; 160mg/ml; 80mg/100ml
Market StatusPrescription
CompanyHospira; Luitpold

2 of 2  
Drug NameDopamine hydrochloride
Drug LabelDopamine Hydrochloride in 5% Dextrose Injection, USP is a sterile, nonpyrogenic, prediluted solution of dopamine hydrochloride in 5% dextrose injection. It is administered by intravenous infusion.Each 100 mL contains dopamine hydrochloride 80 mg (0.8...
Active IngredientDopamine hydrochloride
Dosage FormInjectable
RouteInjection
Strength80mg/ml; 160mg/100ml; 40mg/ml; 160mg/ml; 80mg/100ml
Market StatusPrescription
CompanyHospira; Luitpold

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


Dopamine Agents

Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. (See all compounds classified as Dopamine Agents.)


Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Catecholamines [CS]; Catecholamine [EPC]

API Reference Price

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LIMITED","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"1500","totalValueFC":"16539.8","currency":"EUR","unitRateINR":"136124.4","date":"29-Aug-2023","totalValueINR":"1374994.311","totalValueInUsd":"16539.8","indian_port":"BANGALORE AIR","hs_no":"29221190","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"IBC KNOWLEDGE PARK, PHASE-2, D ,BLOCK, 9TH FLOOR, 4\/1, BANNERGHATTA,RD,OPP:FIRE STATION, , KAR"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699295400,"product":"DOPAMINE HYDROCHLORIDE IP\/USP (CAS NO. 62-31-7)","address":"103,PLOT NO.29, SECTOR 14,","city":"NAVI MUMBAI, MAHARASHTRA","supplier":"RECORDATI","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"VHB MEDI SCIENCES LIMITED","customerCountry":"INDIA","quantity":"35.00","actualQuantity":"35","unit":"KGS","unitRateFc":"400","totalValueFC":"14186.7","currency":"USD","unitRateINR":"33660","date":"07-Nov-2023","totalValueINR":"1178100","totalValueInUsd":"14186.7","indian_port":"Bombay Air","hs_no":"29222990","bill_no":"8666295","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA MEDIANA CISTERNA 4 04011CAMPOVERDE DI APRILIA (LT)SDNF ITALY","customerAddress":"103,PLOT NO.29, SECTOR 14,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722450600,"product":"704241- DOPAMINE HCL -50 KG CUS MAT NO.RAE025SFE BATCH NO. 24012077(DOPAMINE HYDROCHLORIDE PH. EUR )","address":"1\/5, SANTOSH COMPLEX, ARMUGAM","city":"BANGALORE , KARNATAKA","supplier":"SIEGFRIED AG","supplierCountry":"SWITZERLAND","foreign_port":"KEARNEY","customer":"MAIVA PHARMA PRIVATE ","customerCountry":"INDIA","quantity":"2.44","actualQuantity":"2.44","unit":"KGS","unitRateFc":"1500","totalValueFC":"4085.6","currency":"EUR","unitRateINR":"139050","date":"01-Aug-2024","totalValueINR":"339282","totalValueInUsd":"4085.6","indian_port":"Bangalore Air","hs_no":"29221190","bill_no":"4814083","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"KEARNEY","supplierAddress":"UNTERE BRUHISTRASSE 44800 ZOFINGENSWITZERLAND CH","customerAddress":"1\/5, SANTOSH COMPLEX, ARMUGAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722450600,"product":"704241- DOPAMINE HCL -50 KG CUS MAT NO.RAE025SFE BATCH NO. 24012077(DOPAMINE HYDROCHLORIDE PH. EUR )","address":"1\/5, SANTOSH COMPLEX, ARMUGAM","city":"BANGALORE , KARNATAKA","supplier":"SIEGFRIED AG","supplierCountry":"SWITZERLAND","foreign_port":"KEARNEY","customer":"MAIVA PHARMA PRIVATE ","customerCountry":"INDIA","quantity":"7.56","actualQuantity":"7.56","unit":"KGS","unitRateFc":"1500","totalValueFC":"12658.8","currency":"EUR","unitRateINR":"139050","date":"01-Aug-2024","totalValueINR":"1051218","totalValueInUsd":"12658.8","indian_port":"Bangalore Air","hs_no":"29221190","bill_no":"4814083","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"KEARNEY","supplierAddress":"UNTERE BRUHISTRASSE 44800 ZOFINGENSWITZERLAND CH","customerAddress":"1\/5, SANTOSH COMPLEX, ARMUGAM"}]
08-Feb-2021
31-Aug-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - 160MG/100ML

USFDA APPLICATION NUMBER - 18132

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DOSAGE - INJECTABLE;INJECTION - 40MG/ML

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DOSAGE - INJECTABLE;INJECTION - 80MG/100ML

USFDA APPLICATION NUMBER - 18132

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