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    Chemistry

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    Also known as: 62-31-7, 3-hydroxytyramine hydrochloride, Dopamine hcl, Intropin, 4-(2-aminoethyl)benzene-1,2-diol hydrochloride, Cardiosteril
    Molecular Formula
    C8H12ClNO2
    Molecular Weight
    189.64  g/mol
    InChI Key
    CTENFNNZBMHDDG-UHFFFAOYSA-N
    FDA UNII
    7L3E358N9L
    Dopamine
    One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
    1 2D Structure

    Dopamine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-(2-aminoethyl)benzene-1,2-diol;hydrochloride
    2.1.2 InChI
    InChI=1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
    2.1.3 InChI Key
    CTENFNNZBMHDDG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=CC(=C(C=C1CCN)O)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    7L3E358N9L
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 3,4 Dihydroxyphenethylamine

    2. 3,4-dihydroxyphenethylamine

    3. 4-(2-aminoethyl)-1,2-benzenediol

    4. Dopamine

    5. Hydrochloride, Dopamine

    6. Hydroxytyramine

    7. Intropin

    2.3.2 Depositor-Supplied Synonyms

    1. 62-31-7

    2. 3-hydroxytyramine Hydrochloride

    3. Dopamine Hcl

    4. Intropin

    5. 4-(2-aminoethyl)benzene-1,2-diol Hydrochloride

    6. Cardiosteril

    7. Dopastat

    8. Revivan

    9. Inotropin

    10. Tensamin

    11. Dopamine.hcl

    12. 3,4-dihydroxyphenethylamine Hydrochloride

    13. Dynatra

    14. 1,2-benzenediol, 4-(2-aminoethyl)-, Hydrochloride

    15. 4-(2-aminoethyl)pyrocatechol Hydrochloride

    16. (dopamine Hcl)

    17. 2-(3,4-dihydroxyphenyl)ethylamine Hydrochloride

    18. M-hydroxytyramine Hydrochloride

    19. Dopamine (hydrochloride)

    20. 3-hydroxytyramine, Hydrochloride

    21. Asl-279

    22. P 498

    23. 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride

    24. Nsc-169105

    25. Mls000069419

    26. 7l3e358n9l

    27. Smr000059081

    28. Dopamine Chloride

    29. Dopamine Fresenius

    30. 62-31-7 (hcl); 51-61-6 (free Base)

    31. 1200398-97-5

    32. 1,2-benzenediol, 4-(2-aminoethyl)-, Hydrochloride (1:1)

    33. 3-hydroxytyraminium Chloride

    34. Abbodop

    35. Rascordin

    36. Pyrocatechol, 4-(2-aminoethyl)-, Hydrochloride

    37. 1,2-benzenediol, 4-(2-aminoethyl)-, Hydrochloride (1:1), Homopolymer

    38. Nsc169105

    39. Einecs 200-527-8

    40. Nsc 169105

    41. Unii-7l3e358n9l

    42. Sr-01000075366

    43. .beta.-(3,4-dihydroxyphenyl)ethylamine Hydrochloride

    44. Actopamin (tn)

    45. Dopamine Hcl Salt

    46. Intropin (tn)

    47. Beta-(3,4-dihydroxyphenyl)ethylamine Hydrochloride

    48. Dopamine Hydrochloride In Dextrose 5%

    49. Dopamine Hydrochloride And Dextrose 5%

    50. Dopamini Hydrochloridum

    51. 3-hydroxytyramine Hcl

    52. Dopamine Hydrochloride [usan:usp:jan]

    53. 3-hydroxytyramine, Hcl

    54. Opera_id_218

    55. 3,4-dihydroxyphenyl-ethylamine Hydrochloride

    56. Dopamine Hydrogen Chloride

    57. Dsstox_cid_550

    58. Intropin [as Hydrochloride]

    59. Dopamini Hydrochloridum,(s)

    60. Chembl1557

    61. Dsstox_rid_75655

    62. Dsstox_gsid_20550

    63. Schembl40951

    64. 335081-04-4

    65. Mls001074180

    66. Spectrum1500263

    67. Asl279

    68. Chebi:4698

    69. Sgcut00110

    70. Dtxsid7020550

    71. Hy-b0451a

    72. Dopamine Hydrochloride And Dextrose 5% In Plastic Container

    73. Dopamine Hydrochloride In Dextrose 5% In Plastic Container

    74. Dopamine Hydrochloride (inotropin)

    75. Hms1920i18

    76. Kuc104380c

    77. Pharmakon1600-01500263

    78. Dopamine Hydrochloride [mi]

    79. Bcp06611

    80. To_000060

    81. Dopamine Hydrochloride (jp17/usp)

    82. Dopamine Hydrochloride [jan]

    83. Tox21_201018

    84. Tox21_500586

    85. Ccg-40211

    86. Dopamine Hydrochloride [usan]

    87. Nsc756749

    88. S2529

    89. Dopamine Hydrochloride [vandf]

    90. Akos008056421

    91. Dopamine Hydrochloride [mart.]

    92. 1, 4-(2-aminoethyl)-, Hydrochloride

    93. Dopamine Hydrochloride [usp-rs]

    94. Dopamine Hydrochloride [who-dd]

    95. Dopamine Hydrochloride [who-ip]

    96. Ks-5304

    97. Ksc-10-159

    98. Lp00586

    99. Nc00545

    100. Nsc-756749

    101. 3,4-dihydoxyphenethylamine Hydrochloride

    102. Cas-62-31-7

    103. Ncgc00093965-01

    104. Ncgc00093965-02

    105. Ncgc00093965-03

    106. Ncgc00093965-04

    107. Ncgc00258571-01

    108. Ncgc00261271-01

    109. 3,4-dihydroxyphenylethylaminehydrochloride

    110. Ac-12190

    111. Bd166234

    112. Db-023081

    113. Dopamine Hydrochloride [orange Book]

    114. A0305

    115. Am20080715

    116. Dopamine Hydrochloride [ep Monograph]

    117. Eu-0100586

    118. Ft-0603260

    119. Ft-0667775

    120. Ft-0695562

    121. Sw199608-2

    122. Dopamine Hydrochloride [usp Monograph]

    123. Dopamini Hydrochloridum [who-ip Latin]

    124. D00633

    125. F10519

    126. H 8502

    127. 2-(3,4-dihydroxyphenyl)ethyl-1-13c-amine Hcl

    128. 2-(3,4-dihydroxyphenyl)-ethylamine Hydrochloride

    129. A937196

    130. Dopamine Hydrochloride, Puriss., >=98.5% (at)

    131. Sr-01000075366-1

    132. Sr-01000075366-8

    133. Q27268491

    134. F0001-1648

    135. Z262221794

    136. 963ad780-3e96-47b5-9044-7e59f6c84d67

    137. Dopamine Hydrochloride, Certified Reference Material, Tracecert(r)

    138. Dopamine Hydrochloride, British Pharmacopoeia (bp) Reference Standard

    139. Dopamine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    140. Dopamine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    141. Dopamine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    142. Dopamine Hydrochloride Solution, 1.0 Mg/ml In Methanol With 5% 1 M Hcl (as Free Base), Ampule Of 1 Ml, Certified Reference Material

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 189.64 g/mol
    Molecular Formula C8H12ClNO2
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count2
    Exact Mass189.0556563 g/mol
    Monoisotopic Mass189.0556563 g/mol
    Topological Polar Surface Area66.5 Ų
    Heavy Atom Count12
    Formal Charge0
    Complexity119
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameDopamine hydrochloride
    Drug LabelDopamine Hydrochloride in 5% Dextrose Injection, USP is a sterile, nonpyrogenic, prediluted solution of dopamine hydrochloride in 5% dextrose injection. It is administered by intravenous infusion.Each 100 mL contains dopamine hydrochloride 80 mg (0.8...
    Active IngredientDopamine hydrochloride
    Dosage FormInjectable
    RouteInjection
    Strength80mg/ml; 160mg/100ml; 40mg/ml; 160mg/ml; 80mg/100ml
    Market StatusPrescription
    CompanyHospira; Luitpold

    2 of 2  
    Drug NameDopamine hydrochloride
    Drug LabelDopamine Hydrochloride in 5% Dextrose Injection, USP is a sterile, nonpyrogenic, prediluted solution of dopamine hydrochloride in 5% dextrose injection. It is administered by intravenous infusion.Each 100 mL contains dopamine hydrochloride 80 mg (0.8...
    Active IngredientDopamine hydrochloride
    Dosage FormInjectable
    RouteInjection
    Strength80mg/ml; 160mg/100ml; 40mg/ml; 160mg/ml; 80mg/100ml
    Market StatusPrescription
    CompanyHospira; Luitpold

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Sympathomimetics

    Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

    Dopamine Agents

    Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. (See all compounds classified as Dopamine Agents.)

    Cardiotonic Agents

    Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Catecholamines [CS]; Catecholamine [EPC]

    API Reference Price

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LTD","customerCountry":"INDIA","quantity":"170.00","actualQuantity":"170","unit":"KGS","unitRateFc":"500","totalValueFC":"85307.1","currency":"USD","unitRateINR":"41299.2","date":"04-Aug-2023","totalValueINR":"7091788","totalValueInUsd":"85307.1","indian_port":"SAHAR AIR","hs_no":"29222990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"KALPATARU INSPIRE, 3RD FLOOR, OFF, WESTERN EXPRESS HIGHWAY SANTACRUZ E"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722450600,"product":"704241- DOPAMINE HCL -50 KG CUS MAT NO.RAE025SFE BATCH NO. 24012077(DOPAMINE HYDROCHLORIDE PH. EUR )","address":"1\/5, SANTOSH COMPLEX, ARMUGAM","city":"BANGALORE , KARNATAKA","supplier":"SIEGFRIED AG","supplierCountry":"SWITZERLAND","foreign_port":"KEARNEY","customer":"MAIVA PHARMA PRIVATE ","customerCountry":"INDIA","quantity":"2.44","actualQuantity":"2.44","unit":"KGS","unitRateFc":"1500","totalValueFC":"4085.6","currency":"EUR","unitRateINR":"139050","date":"01-Aug-2024","totalValueINR":"339282","totalValueInUsd":"4085.6","indian_port":"Bangalore Air","hs_no":"29221190","bill_no":"4814083","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"KEARNEY","supplierAddress":"UNTERE BRUHISTRASSE 44800 ZOFINGENSWITZERLAND CH","customerAddress":"1\/5, SANTOSH COMPLEX, ARMUGAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722450600,"product":"704241- DOPAMINE HCL -50 KG CUS MAT NO.RAE025SFE BATCH NO. 24012077(DOPAMINE HYDROCHLORIDE PH. EUR )","address":"1\/5, SANTOSH COMPLEX, ARMUGAM","city":"BANGALORE , KARNATAKA","supplier":"SIEGFRIED AG","supplierCountry":"SWITZERLAND","foreign_port":"KEARNEY","customer":"MAIVA PHARMA PRIVATE ","customerCountry":"INDIA","quantity":"7.56","actualQuantity":"7.56","unit":"KGS","unitRateFc":"1500","totalValueFC":"12658.8","currency":"EUR","unitRateINR":"139050","date":"01-Aug-2024","totalValueINR":"1051218","totalValueInUsd":"12658.8","indian_port":"Bangalore Air","hs_no":"29221190","bill_no":"4814083","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"KEARNEY","supplierAddress":"UNTERE BRUHISTRASSE 44800 ZOFINGENSWITZERLAND CH","customerAddress":"1\/5, SANTOSH COMPLEX, ARMUGAM"}]
    08-Feb-2021
    31-Aug-2024
    KGS
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    Average Price (USD/KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

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    (USD/KGS)    		 Number of Transactions

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    DOSAGE - INJECTABLE;INJECTION - 160MG/100ML

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    DOSAGE - INJECTABLE;INJECTION - 80MG/100ML

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