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ACTIVE PHARMA INGREDIENTS

8 API Suppliers, 1 USDMF, 3 EU WC, 1 NDC API, 6 Listed Suppliers, $ API Reference Price

8 API Suppliers
1 USDMF
3 EU WC
1 NDC API
6 Listed Suppliers
$ API Reference Price

INTERMEDIATES

3 Intermediates Suppliers

3 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

1 FDF Dossiers, 1 Listed Dossiers

1 FDF Dossiers
1 Listed Dossiers

MARKET PLACE

3 APIs

marketPlace
3 APIs

REF. STANDARDS & IMPURITIES

2 Others

otherSolutions
2 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 14008-44-7, Vogalene, Exp 999, 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide, Exp-999, 4-piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]-

Molecular Formula

C₂₂H₂₇N₃O₃S₂

Molecular Weight

445.6 g/mol

InChI Key

BQDBKDMTIJBJLA-UHFFFAOYSA-N

FDA UNII

238S75V9AV

1 2D Structure

Metopimazine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide

2.1.2 InChI

InChI=1S/C22H27N3O3S2/c1-30(27,28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)

2.1.3 InChI Key

BQDBKDMTIJBJLA-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CS(=O)(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCC(CC4)C(=O)N

2.2 Other Identifiers

2.2.1 UNII

238S75V9AV

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 1-(3-(2-methylsulfonylphenothiazin-10-yl) Propyl)isonipecotinamide

2. Metopimazine Hydrochloride

3. Vogalene

2.3.2 Depositor-Supplied Synonyms

1. 14008-44-7

2. Vogalene

3. Exp 999

4. 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide

5. Exp-999

6. 4-piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]-

7. 1-(3-(2-(methylsulfonyl)phenothiazin-10-yl)propyl)isonipecotamide

8. 238s75v9av

9. 4-piperidinecarboxamide, 1-(3-(2-(methylsulfonyl)-10h-phenothiazin-10-yl)propyl)-

10. Rp-9965

11. Nortrip

12. 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide

13. 1-(3-(2-(methylsulfonyl)-10h-phenothiazin-10-yl)propyl)-4-piperidinecarboxamide

14. 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide

15. Metopimazina

16. Metopimazinum

17. Metopimazinum [inn-latin]

18. Metopimazina [inn-spanish]

19. Rp 9965

20. Einecs 237-818-4

21. Brn 4278585

22. Unii-238s75v9av

23. Metopimazine [usan:inn:ban]

24. 1-(3-(2-(methylsulfonyl)-10h-phenothiazin-10-yl)propyl)piperidin-4-carboxamide

25. 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]piperidin-4-carboxamide

26. 2-methylsulfonyl-10-(3-(4-carbamoylpiperidino)propyl)phenothiazine

27. Metopimazine [mi]

28. 10-(3-(4-carbamoylpiperidine)propyl)-2-(methanesulfonyl)phenothiazine

29. Phenothiazine, 10-(3-(4'-carbamoylpiperidino)propyl)-2-methylsulfonyl-

30. Metopimazine (usan/inn)

31. Metopimazine [inn]

32. 1-(3-(2-(methylsulfonyl)phenothiazin-10-yl)propyl)-4-piperidinecarboxamide

33. 4-piperidinecarboxamide, 1-(3-(2-(methanesulfonyl)phenothiazin-10-yl)propyl)-

34. Metopimazine [usan]

35. Schembl49905

36. Metopimazine [mart.]

37. Metopimazine [who-dd]

38. Chembl398615

39. Bdbm82383

40. Gtpl11140

41. Dtxsid80161224

42. Chebi:135726

43. Bdbm179867

44. Zinc537996

45. Cas_26388

46. Ng-101

47. Nsc_26388

48. Akos005065914

49. Isonipecotamide, 1-(3-(2-(methylsulfonyl)phenothiazin-10-yl)propyl)-

50. Bcp9000921

51. Db13591

52. Us9132134, Metopimazine (ng101)

53. Ft-0672379

54. Ft-0672380

55. D05010

56. Q194682

57. J-007351

58. 1-(3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl)-4-piperidinecarboxamide #

2.4 Create Date

2005-03-27

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₇N₃O₃S₂
Molecular Weight	445.6 g/mol
XLogP3	3.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	445.14938408 g/mol
Monoisotopic Mass	445.14938408 g/mol
Topological Polar Surface Area	117 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	703
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antiemetics

Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)

4.2 ATC Code

A - Alimentary tract and metabolism

A04 - Antiemetics and antinauseants

A04A - Antiemetics and antinauseants

A04AD - Other antiemetics

A04AD05 - Metopimazine

API SUPPLIERS

01

M2i Group

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #4B109

M2i Group, an integrated CDMO, is your French partner for development & manufacturing in fine chemistry.

Contact Supplier

France

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

RHODIA INC US 08512-7500 Cranbury

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

03

AXYNTIS Group

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

04

Aesica Pharmaceuticals Limited

United Kingdom

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

05

Lab Service

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

06

Centaur Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

07

Global Calcium

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

08

Global Calcium

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BioProcess International

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

01

Rhodia Inc

U.S.A

BioProcess International

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

EU WC

01

Centaur Pharmaceuticals

India

BioProcess International

Not Confirmed

02

Global Calcium

India

BioProcess International

Not Confirmed

03

Global Calcium

India

BioProcess International

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

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